Clinical and Epidemiologic Research

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Clinical and Epidemiologic Research August 2021

COVID-19 Home Quarantine Accelerated the Progression of Myopia in Children Aged 7 to 12 Years in China

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Mingming Ma; Shuyu Xiong; Shuzhi Zhao; Zhi Zheng; Tao Sun; Chunxia Li
TAGS: child, china, coronavirus pandemic, covid-19, myopia, quarantine
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):37. doi: https://doi.org/10.1167/iovs.62.10.37

Includes: Supplemental Content

Clinical and Epidemiologic Research August 2021

Myopia Progression as a Function of Sex, Age, and Ethnicity

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Lisa A. Jones-Jordan; Loraine T. Sinnott; Raymond H. Chu; Susan A. Cotter; Robert N. Kleinstein; Ruth E. Manny; Donald O. Mutti; J. Daniel Twelker; Karla Zadnik; for the CLEERE Study Group
TAGS: ethnic group, myopia, child
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):36. doi: https://doi.org/10.1167/iovs.62.10.36

Articles August 2021

Deep Learning for Automated Diabetic Retinopathy Screening Fused With Heterogeneous Data From EHRs Can Lead to Earlier Referral Decisions

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Min-Yen Hsu; Jeng-Yuan Chiou; Jung-Tzu Liu; Chee-Ming Lee; Ya-Wen Lee; Chien-Chih Chou; Shih-Chang Lo; Edy Kornelius; Yi-Sun Yang; Sung-Yen Chang; Yu-Cheng Liu; Chien-Ning Huang; Vincent S. Tseng
TAGS: deep learning, diabetic retinopathy screening, electronic medical records, heterogeneity, patient referral
Trans. Vis. Sci. Tech.. 2021; 10(9):18. doi: https://doi.org/10.1167/tvst.10.9.18

Clinical and Epidemiologic Research August 2021

The Protective Effect of Metformin Use on Early Nd:YAG Laser Capsulotomy

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Jennifer L. Patnaik; Karen L. Christopher; Michelle G. Pedler; Biehuoy Shieh; Carson C. Petrash; Brandie D. Wagner; Naresh Mandava; Anne M. Lynch; Alan G. Palestine; J. Mark Petrash
TAGS: metformin, nd-yag lasers, cohort studies, mice
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):24. doi: https://doi.org/10.1167/iovs.62.10.24

Clinical and Epidemiologic Research August 2021

Fine Particulate Matter and Age-Related Eye Disease: The Canadian Longitudinal Study on Aging

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Alyssa Grant; Gareth Leung; Marie-Josée Aubin; Marie-Jeanne Kergoat; Gisèle Li; Ellen E. Freeman
TAGS: aging, eye diseases, longitudinal studies, particulate matter, glaucoma, visual impairment, health, intraocular pressure, cataract
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):7. doi: https://doi.org/10.1167/iovs.62.10.7

Articles July 2021

New Polygenic Risk Score to Predict High Myopia in Singapore Chinese Children

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Carla Lanca; Irfahan Kassam; Karina Patasova; Li-Lian Foo; Jonathan Li; Marcus Ang; Quan V. Hoang; Yik-Ying Teo; Pirro G. Hysi; Seang-Mei Saw
TAGS: child, chinese (other dialects), myopia, singapore, chinese people, cohort studies
Trans. Vis. Sci. Tech.. 2021; 10(8):26. doi: https://doi.org/10.1167/tvst.10.8.26

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2021

Differences in Retinal and Choroidal Vasculature and Perfusion Related to Axial Length in Pediatric Anisomyopes

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Hao Wu; Zhu Xie; Pengqi Wang; Mengqi Liu; Yuanyuan Wang; Jiadi Zhu; Xiangqin Chen; Zhiqiang Xu; Xinjie Mao; Xiangtian Zhou
TAGS: choroidal circulation, myopia, pediatrics, perfusion, vasculature, eye
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):40. doi: https://doi.org/10.1167/iovs.62.9.40

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2021

Serum and Macular Carotenoids in Relation to Retinal Vessel Caliber Fifteen Years Later, in the Second Carotenoids in Age-Related Eye Disease Study

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Thomas Lawler; Jackson Korger; Yao Liu; Zhe Liu; Jeong W. Pak; Nancy Barrett; Barbara Blodi; Amitha Domalpally; Elizabeth Johnson; Robert Wallace; Julie A. Mares; for the Carotenoids in Age-Related Eye Disease Study Investigators
TAGS: carotenoids, eye diseases, retinal vascular caliber
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):20. doi: https://doi.org/10.1167/iovs.62.9.20

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2021

Environmental and Nutritional Determinants of Macular Pigment in a Mexican Population

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Marina Green-Gomez; Rachel Moran; James Stringham; Cesar Hernández-Alcaraz; Kenny Mendoza-Herrera; J. Jans Fromow-Guerra; Alfonso Prado-Cabrero; John Nolan
TAGS: carotenoids, diet, macular pigment, mexico
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):18. doi: https://doi.org/10.1167/iovs.62.9.18

Articles June 2021

Growth Modeling for Quantitative, Spatially Resolved Geographic Atrophy Lesion Kinetics

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Eric M. Moult; Yunchan Hwang; Yingying Shi; Liang Wang; Siyu Chen; Nadia K. Waheed; Giovanni Gregori; Philip J. Rosenfeld; James G. Fujimoto
TAGS: atrophy, eye, growth rate, kinetics
Trans. Vis. Sci. Tech.. 2021; 10(7):26. doi: https://doi.org/10.1167/tvst.10.7.26

Includes: Supplemental Content

Articles June 2021

Clinical Ocular Diagnostic Model of Marfan Syndrome in Patients With Congenital Ectopia Lentis by Pentacam AXL System

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Tianhui Chen; Jiahui Chen; Guangming Jin; Min Zhang; Zexu Chen; Danying Zheng; Yongxiang Jiang
TAGS: cohort studies, ectopia lentis, marfan syndrome, training, myopia
Trans. Vis. Sci. Tech.. 2021; 10(7):3. doi: https://doi.org/10.1167/tvst.10.7.3

Articles May 2021

Automated Identification of Referable Retinal Pathology in Teleophthalmology Setting

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Qitong Gao; Joshua Amason; Scott Cousins; Miroslav Pajic; Majda Hadziahmetovic
TAGS: datasets, pathology, training, diagnostic imaging
Trans. Vis. Sci. Tech.. 2021; 10(6):30. doi: https://doi.org/10.1167/tvst.10.6.30

Includes: Supplemental Content

Clinical and Epidemiologic Research May 2021

Swept-Source OCT Angiographic Characteristics of Treatment-Naïve Nonexudative Macular Neovascularization in AMD Prior to Exudation

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Mengxi Shen; Qinqin Zhang; Jin Yang; Hao Zhou; Zhongdi Chu; Xiao Zhou; William Feuer; Xiaoshuang Jiang; Yingying Shi; Luis de Sisternes; Mary K. Durbin; Ruikang K. Wang; Giovanni Gregori; Philip J. Rosenfeld
TAGS: angiogram, chief complaint, eye, fluid flow, neovascularization, pathologic, ventricular septal defect, volume, cortical blindness, face, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2021; 62(6):14. doi: https://doi.org/10.1167/iovs.62.6.14

Articles May 2021

Longitudinal Study of Retinal Structure, Vascular, and Neuronal Function in Patients With Relapsing-Remitting Multiple Sclerosis: 1-Year Follow-Up

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Qi Chen; Hong Jiang; Silvia Delgado; Jeffrey Hernandez; Diego Eduardo Alba; Giovanni Gregori; Kottil W. Rammohan; Vittorio Porciatti; Jianhua Wang
TAGS: follow-up, longitudinal studies, multiple sclerosis, relapsing-remitting, retina, eye, medical history
Trans. Vis. Sci. Tech.. 2021; 10(6):6. doi: https://doi.org/10.1167/tvst.10.6.6

Clinical and Epidemiologic Research May 2021

Small Nerve Fiber Damage and Langerhans Cells in Type 1 and Type 2 Diabetes and LADA Measured by Corneal Confocal Microscopy

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Luca D'Onofrio; Alise Kalteniece; Maryam Ferdousi; Shazli Azmi; Ioannis N. Petropoulos; Georgios Ponirakis; Uazman Alam; Omar Asghar; Andrew Marshall; Andrew J.M. Boulton; Nathan Efron; Raffaella Buzzetti; Handrean Soran; Rayaz A. Malik
TAGS: anterior descending branch of left coronary artery, cornea, diabetes mellitus, type 2, langerhans cell, microscopy, confocal, nerve fibers, neurons, nervousness
Invest. Ophthalmol. Vis. Sci.. 2021; 62(6):5. doi: https://doi.org/10.1167/iovs.62.6.5

Clinical and Epidemiologic Research April 2021

Rapid Myopic Progression in Childhood Is Associated With Teenage High Myopia

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Carla Lanca; Li-Lian Foo; Marcus Ang; Chuen-Seng Tan; Biten Kathrani; Hla Myint Htoon; Donald Tan; Quan V. Hoang; Noel Brennan; Seang-Mei Saw; Charumathi Sabanayagam
TAGS: adolescent, child, myopia
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):17. doi: https://doi.org/10.1167/iovs.62.4.17

Clinical and Epidemiologic Research April 2021

Higher Serum Uric Acid Levels Are Associated With an Increased Risk of Vision-Threatening Diabetic Retinopathy in Type 2 Diabetes Patients

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Yanan Hu; Zhulin Chan; Chunxia Li; Ya Shi; Xinping She; Chufeng Gu; Yujie Wang; Chuandi Zhou; Shuzhi Zhao; Zhi Zheng; Haibing Chen
TAGS: diabetes mellitus, type 2, diabetic retinopathy, hyperuricemia, urate measurement, serum, uric acid, vision
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):23. doi: https://doi.org/10.1167/iovs.62.4.23

Includes: Supplemental Content

Clinical and Epidemiologic Research April 2021

Correction of Low-Moderate Hyperopia Improves Accommodative Function for Some Hyperopic Children During Sustained Near Work

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Michael Ntodie; Kathryn J. Saunders; Julie-Anne Little
TAGS: child, hyperopia, reading (activity), visual accommodation
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):6. doi: https://doi.org/10.1167/iovs.62.4.6

Articles March 2021

Macular Thickness Profile and Its Association With Best-Corrected Visual Acuity in Healthy Young Adults

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Samantha Sze-Yee Lee; Gareth Lingham; David Alonso-Caneiro; Jason Charng; Fred Kuanfu Chen; Seyhan Yazar; David Anthony Mackey
TAGS: macula lutea, retina, visual acuity, young adult, eye, cohort studies, fovea centralis, ophthalmic examination and evaluation, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2021; 10(3):8. doi: https://doi.org/10.1167/tvst.10.3.8

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2021

Association Between Medication-Taking and Refractive Error in a Large General Population-Based Cohort

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Karina Patasova; Anthony P. Khawaja; Bani Tamraz; Katie M. Williams; Omar A. Mahroo; Maxim Freidin; Ameenat L. Solebo; Jelle Vehof; Mario Falchi; Jugnoo S. Rahi; Chris J. Hammond; Pirro G. Hysi
TAGS: cohort studies, pharmaceutical preparations, refraction, refractive errors, drug usage, protein electrophoresis, serum
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):15. doi: https://doi.org/10.1167/iovs.62.2.15

Includes: Supplemental Content

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COVID-19 Home Quarantine Accelerated the Progression of Myopia in Children Aged 7 to 12 Years in China

Myopia Progression as a Function of Sex, Age, and Ethnicity

Deep Learning for Automated Diabetic Retinopathy Screening Fused With Heterogeneous Data From EHRs Can Lead to Earlier Referral Decisions

The Protective Effect of Metformin Use on Early Nd:YAG Laser Capsulotomy

Fine Particulate Matter and Age-Related Eye Disease: The Canadian Longitudinal Study on Aging

New Polygenic Risk Score to Predict High Myopia in Singapore Chinese Children

Differences in Retinal and Choroidal Vasculature and Perfusion Related to Axial Length in Pediatric Anisomyopes

Serum and Macular Carotenoids in Relation to Retinal Vessel Caliber Fifteen Years Later, in the Second Carotenoids in Age-Related Eye Disease Study

Environmental and Nutritional Determinants of Macular Pigment in a Mexican Population

Growth Modeling for Quantitative, Spatially Resolved Geographic Atrophy Lesion Kinetics

Clinical Ocular Diagnostic Model of Marfan Syndrome in Patients With Congenital Ectopia Lentis by Pentacam AXL System

Automated Identification of Referable Retinal Pathology in Teleophthalmology Setting

Swept-Source OCT Angiographic Characteristics of Treatment-Naïve Nonexudative Macular Neovascularization in AMD Prior to Exudation

Longitudinal Study of Retinal Structure, Vascular, and Neuronal Function in Patients With Relapsing-Remitting Multiple Sclerosis: 1-Year Follow-Up

Small Nerve Fiber Damage and Langerhans Cells in Type 1 and Type 2 Diabetes and LADA Measured by Corneal Confocal Microscopy

Rapid Myopic Progression in Childhood Is Associated With Teenage High Myopia

Higher Serum Uric Acid Levels Are Associated With an Increased Risk of Vision-Threatening Diabetic Retinopathy in Type 2 Diabetes Patients

Correction of Low-Moderate Hyperopia Improves Accommodative Function for Some Hyperopic Children During Sustained Near Work

Macular Thickness Profile and Its Association With Best-Corrected Visual Acuity in Healthy Young Adults

Association Between Medication-Taking and Refractive Error in a Large General Population-Based Cohort

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