External Eye Disease

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Articles April 2021

A Novel Rabbit Dry Eye Model Induced by a Controlled Drying System

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Xiao-Min Chen; Jian-Biao Kuang; Hui-Yin Yu; Zhen-Ning Wu; Shu-Yi Wang; Shi-You Zhou
TAGS: conjunctiva, cornea, desiccation, dry eye syndromes, eye, lacrimal gland, oryctolagus cuniculus, proteins, fluorescein stain method, tear production
Trans. Vis. Sci. Tech.. 2021; 10(4):32. doi: https://doi.org/10.1167/tvst.10.4.32

Articles April 2021

Smart Eye Camera: A Validation Study for Evaluating the Tear Film Breakup Time in Human Subjects

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Eisuke Shimizu; Hiroyuki Yazu; Naohiko Aketa; Ryota Yokoiwa; Shinri Sato; Taiichiro Katayama; Akiko Hanyuda; Yasunori Sato; Yoko Ogawa; Kazuo Tsubota
TAGS: dry eye syndromes, eye, microscopes, slit lamps, tear film finding, validation studies
Trans. Vis. Sci. Tech.. 2021; 10(4):28. doi: https://doi.org/10.1167/tvst.10.4.28

Includes: Multimedia, Supplemental Content

Articles April 2021

Improvement of Evaporative Dry Eye With Meibomian Gland Dysfunction in Model Mice by Treatment With Ophthalmic Solution Containing Mineral Oil

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Keisuke Watanabe; Masataka Yoshida; Takashi Okumura; Takayuki Sassa; Akio Kihara; Akira Uchiyama
TAGS: dry eye syndromes, meibomian gland dysfunction, mice, mineral oil, ophthalmic solutions, meibomian gland
Trans. Vis. Sci. Tech.. 2021; 10(4):21. doi: https://doi.org/10.1167/tvst.10.4.21

Articles March 2021

Face Mask-Related Ocular Surface Modifications During COVID-19 Pandemic: A Clinical, In Vivo Confocal Microscopy, and Immune-Cytology Study

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Leonardo Mastropasqua; Manuela Lanzini; Lorenza Brescia; Rossella D'Aloisio; Mario Nubile; Marco Ciancaglini; Claudio D'Amario; Luca Agnifili; Rodolfo Mastropasqua
TAGS: coronavirus pandemic, covid-19, cytology, face, masks, microscopy, confocal, hla-dr antigens, dry eye syndromes, conjunctiva, questionnaires
Trans. Vis. Sci. Tech.. 2021; 10(3):22. doi: https://doi.org/10.1167/tvst.10.3.22

Articles February 2021

Meibography Phenotyping and Classification From Unsupervised Discriminative Feature Learning

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Chun-Hsiao Yeh; Stella X. Yu; Meng C. Lin
TAGS: learning, phenotype determination, atrophy, datasets
Trans. Vis. Sci. Tech.. 2021; 10(2):4. doi: https://doi.org/10.1167/tvst.10.2.4

Articles August 2020

A Novel Quantitative Index of Meibomian Gland Dysfunction, the Meibomian Gland Tortuosity

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Xiaolei Lin; Yana Fu; Lu Li; Chaoqiao Chen; Xuewen Chen; Yingyu Mao; Hengli Lian; Weihua Yang; Qi Dai
TAGS: meibomian gland, meibomian gland dysfunction
Trans. Vis. Sci. Tech.. 2020; 9(9):34. doi: https://doi.org/10.1167/tvst.9.9.34

Articles August 2020

Development of a Quantitative Immunoassay for Tear Lacritin Proteoforms

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Brooke M. Justis; Casey E. Coburn; Ethan M. Tyler; Ryan S. Showalter; Brianna J. Dissler; Melissa Li; Nancy A. McNamara; Gordon W. Laurie; Robert L. McKown
TAGS: antibodies, immunoassay, proteins, schirmer tear test procedure, protein measurement, total, western blotting, recovery of function, volume
Trans. Vis. Sci. Tech.. 2020; 9(9):13. doi: https://doi.org/10.1167/tvst.9.9.13

Articles July 2020

Intravitreal Injection with a Conjunctival Injection Device: A Single-Center Experience

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Yu Qiang Soh; Nathalie Pei Yu Chiam; Andrew Shih Hsiang Tsai; Gemmy Chui Ming Cheung; Tien Yin Wong; Ian Yew San Yeo; Edmund Yick Mun Wong; Anna Cheng Sim Tan
TAGS: conjunctival injection, injections, intravitreal injections, surgeons
Trans. Vis. Sci. Tech.. 2020; 9(8):28. doi: https://doi.org/10.1167/tvst.9.8.28

Articles April 2020

Climatic and Environmental Correlates of Dry Eye Disease Severity: A Report From the Dry Eye Assessment and Management (DREAM) Study

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Erich J. Berg; Gui-shuang Ying; Maureen G. Maguire; Perry E. Sheffield; Loretta B. Szczotka-Flynn; Penny A. Asbell; Joanne F. Shen; the DREAM Study Research Group
TAGS: dreams, dry eye syndromes, signs and symptoms, climate
Trans. Vis. Sci. Tech.. 2020; 9(5):25. doi: https://doi.org/10.1167/tvst.9.5.25

Includes: Supplemental Content

Articles February 2020

Dupilumab-Associated Mucin Deficiency (DAMD)

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Brad P. Barnett; Natalie A. Afshari
TAGS: dupilumab, mucins, questionnaires, signs and symptoms
Trans. Vis. Sci. Tech.. 2020; 9(3):29. doi: https://doi.org/10.1167/tvst.9.3.29

Includes: Supplemental Content

Articles December 2019

A Deep Learning Approach for Meibomian Gland Atrophy Evaluation in Meibography Images

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Jiayun Wang; Thao N. Yeh; Rudrasis Chakraborty; Stella X. Yu; Meng C. Lin
TAGS: atrophy, deep learning, meibomian gland
Trans. Vis. Sci. Tech.. 2019; 8(6):37. doi: https://doi.org/10.1167/tvst.8.6.37

Articles December 2019

Assessment of Corneal Fluorescein Staining in Different Dry Eye Subtypes Using Digital Image Analysis

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Marco Pellegrini; Federico Bernabei; Fabiana Moscardelli; Aldo Vagge; Riccardo Scotto; Cristina Bovone; Vincenzo Scorcia; Giuseppe Giannaccare
TAGS: cornea, digital image analysis, dry eye syndromes, fluorescein stain method, reliability
Trans. Vis. Sci. Tech.. 2019; 8(6):34. doi: https://doi.org/10.1167/tvst.8.6.34

Articles November 2019

The Role of Meibography in the Diagnosis of Meibomian Gland Dysfunction in Ocular Surface Diseases

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Mathieu Robin; Hong Liang; Ghislaine Rabut; Edouard Augstburger; Christophe Baudouin; Antoine Labbé
TAGS: meibomian gland, pathophysiology, hypersensitivity, schirmer tear test procedure, signs and symptoms
Trans. Vis. Sci. Tech.. 2019; 8(6):6. doi: https://doi.org/10.1167/tvst.8.6.6

Articles November 2019

Efficacy of Strip Meniscometry for Detecting Lacrimal Obstructive Diseases Among Patients With Epiphora

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Sho Ishikawa; Takuhei Shoji; Norihiro Yamada; Kei Shinoda
TAGS: excessive tearing, trimethylamine, tissue microarray, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2019; 8(6):8. doi: https://doi.org/10.1167/tvst.8.6.8

Articles October 2019

Spatial Distribution of Noninvasive Break Up Times and Clinical Relevance in Healthy Participants and Mild Dry Eye

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Louis Tong; Calesta Hui Yi Teo; Ryan Khee Jin Lee
TAGS: dry eye syndromes, lipids, signs and symptoms, eye
Trans. Vis. Sci. Tech.. 2019; 8(5):30. doi: https://doi.org/10.1167/tvst.8.5.30

Articles August 2019

Potential Effect of Epilation on the Outcome of Surgery for Trachomatous Trichiasis

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Sandra Liliana Talero; Beatriz Muñoz; Sheila K. West
TAGS: eyelid trichiasis, general hair removal - epilation, surgical outcome, surgical procedures, operative, entropion
Trans. Vis. Sci. Tech.. 2019; 8(4):30. doi: https://doi.org/10.1167/tvst.8.4.30

Articles June 2019

Human Lacrimal Production Rate and Wetted Length of Modified Schirmer's Tear Test Strips

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Young Hyun Kim; Andrew D. Graham; Wing Li; Clayton J. Radke; Meng C. Lin
TAGS: evaporation, eye, heterogeneity of variance, loa, sample size, tear production, dry eye syndromes, humidity, reading (activity), anesthetics
Trans. Vis. Sci. Tech.. 2019; 8(3):40. doi: https://doi.org/10.1167/tvst.8.3.40

Clinical Trials May 2019

A Phase I/II Placebo-Controlled Randomized Pilot Clinical Trial of Recombinant Deoxyribonuclease (DNase) Eye Drops Use in Patients With Dry Eye Disease

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Christine Mun; Shilpa Gulati; Sapna Tibrewal; Yi-Fan Chen; Seungwon An; Bayasgalan Surenkhuu; Ilangovan Raju; Morgan Buwick; Anna Ahn; Ji-Eun Kwon; Nour Atassi; Anubhav Pradeep; Damiano Rondelli; Sandeep Jain
TAGS: deoxyribonucleases, dry eye syndromes, eyedrops, placebos, deoxyribonuclease i
Trans. Vis. Sci. Tech.. 2019; 8(3):10. doi: https://doi.org/10.1167/tvst.8.3.10

Articles February 2019

Multimodal Assessment of Corneal Erosions Using Optical Coherence Tomography and Automated Grading of Fluorescein Staining in a Rabbit Dry Eye Model

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Ifat Sher; Adi Tzameret; Alicja M. Szalapak; Tomer Carmeli; Estela Derazne; Noa Avni-Zauberman; Arie L. Marcovich; Guy Ben Simon; Ygal Rotenstreich
TAGS: cornea, dry eye syndromes, erosion, fluorescein stain method, optical coherence tomography, oryctolagus cuniculus, epithelium, fluorescein, software, desiccation
Trans. Vis. Sci. Tech.. 2019; 8(1):27. doi: https://doi.org/10.1167/tvst.8.1.27

Includes: Supplemental Content

Articles December 2018

The Relationship of Dry Eye Disease with Depression and Anxiety: A Naturalistic Observational Study

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Momoko Kitazawa; Chiaki Sakamoto; Michitaka Yoshimura; Motoko Kawashima; Sachiko Inoue; Masaru Mimura; Kazuo Tsubota; Kazuno Negishi; Taishiro Kishimoto
TAGS: anxiety, depressive disorders, dry eye syndromes, signs and symptoms
Trans. Vis. Sci. Tech.. 2018; 7(6):35. doi: https://doi.org/10.1167/tvst.7.6.35

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A Novel Rabbit Dry Eye Model Induced by a Controlled Drying System

Smart Eye Camera: A Validation Study for Evaluating the Tear Film Breakup Time in Human Subjects

Improvement of Evaporative Dry Eye With Meibomian Gland Dysfunction in Model Mice by Treatment With Ophthalmic Solution Containing Mineral Oil

Face Mask-Related Ocular Surface Modifications During COVID-19 Pandemic: A Clinical, In Vivo Confocal Microscopy, and Immune-Cytology Study

Meibography Phenotyping and Classification From Unsupervised Discriminative Feature Learning

A Novel Quantitative Index of Meibomian Gland Dysfunction, the Meibomian Gland Tortuosity

Development of a Quantitative Immunoassay for Tear Lacritin Proteoforms

Intravitreal Injection with a Conjunctival Injection Device: A Single-Center Experience

Climatic and Environmental Correlates of Dry Eye Disease Severity: A Report From the Dry Eye Assessment and Management (DREAM) Study

Dupilumab-Associated Mucin Deficiency (DAMD)

A Deep Learning Approach for Meibomian Gland Atrophy Evaluation in Meibography Images

Assessment of Corneal Fluorescein Staining in Different Dry Eye Subtypes Using Digital Image Analysis

The Role of Meibography in the Diagnosis of Meibomian Gland Dysfunction in Ocular Surface Diseases

Efficacy of Strip Meniscometry for Detecting Lacrimal Obstructive Diseases Among Patients With Epiphora

Spatial Distribution of Noninvasive Break Up Times and Clinical Relevance in Healthy Participants and Mild Dry Eye

Potential Effect of Epilation on the Outcome of Surgery for Trachomatous Trichiasis

Human Lacrimal Production Rate and Wetted Length of Modified Schirmer's Tear Test Strips

A Phase I/II Placebo-Controlled Randomized Pilot Clinical Trial of Recombinant Deoxyribonuclease (DNase) Eye Drops Use in Patients With Dry Eye Disease

Multimodal Assessment of Corneal Erosions Using Optical Coherence Tomography and Automated Grading of Fluorescein Staining in a Rabbit Dry Eye Model

The Relationship of Dry Eye Disease with Depression and Anxiety: A Naturalistic Observational Study

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