Genetics

Showing 1 – 20 of 134

SORT: Best Match Most Recent Oldest

VIEW: Basic | Expanded

Articles October 2020

Laser Capture Microdissection-Based RNA Microsequencing Reveals Optic Nerve Crush-Related Early mRNA Alterations in Retinal Ganglion Cell Layer

PDF

Dongyan Pan; Mengqiao Xu; Xin Chang; Mao Xia; Yibin Fang; Yinghua Fu; Wei Shen; Yue Wang; Xiaodong Sun
TAGS: lasers, microdissection, optic nerve, rna, rna, messenger, retinal ganglion cells, genes, sequence analysis, rna
Trans. Vis. Sci. Tech.. 2020; 9(11):30. doi: https://doi.org/10.1167/tvst.9.11.30

Includes: Supplemental Content

Special Issue October 2020

Artificial Intelligence for Automated Overlay of Fundus Camera and Scanning Laser Ophthalmoscope Images

PDF

Melina Cavichini; Cheolhong An; Dirk-Uwe G. Bartsch; Mahima Jhingan; Manuel J. Amador-Patarroyo; Christopher P. Long; Junkang Zhang; Yiqian Wang; Alison X. Chan; Samantha Madala; Truong Nguyen; William R. Freeman
TAGS: artificial intelligence, lasers, ophthalmoscopes, scanning laser ophthalmoscopy, diagnostic imaging
Trans. Vis. Sci. Tech.. 2020; 9(2):56. doi: https://doi.org/10.1167/tvst.9.2.56

Articles October 2020

Protein Composition of the Subretinal Fluid Suggests Selective Diffusion of Vitreous Proteins in Retinal Detachment

PDF

Ebbe Toftgaard Poulsen; Xhevat Lumi; Anders K. Hansen; Jan J. Enghild; Goran Petrovski
TAGS: proteins, vitreous body, retinal detachment, proteomics
Trans. Vis. Sci. Tech.. 2020; 9(11):16. doi: https://doi.org/10.1167/tvst.9.11.16

Includes: Supplemental Content

Articles October 2020

Transgenic Expression of Cacna1f Rescues Vision and Retinal Morphology in a Mouse Model of Congenital Stationary Night Blindness 2A (CSNB2A)

PDF

Derek M. Waldner; Kenichi Ito; Li-Li Chen; Lisa Nguyen; Robert L. Chow; Amy Lee; Derrick E. Rancourt; Francois Tremblay; William K. Stell; N. Torben Bech-Hansen
TAGS: animals, transgenic, language morphology, mice, morphology, night blindness, congenital stationary, pax6 transcription factor, retina, transgenes, vision
Trans. Vis. Sci. Tech.. 2020; 9(11):19. doi: https://doi.org/10.1167/tvst.9.11.19

Includes: Supplemental Content

Articles October 2020

Retinal Boundary Segmentation in Stargardt Disease Optical Coherence Tomography Images Using Automated Deep Learning

PDF

Jason Kugelman; David Alonso-Caneiro; Yi Chen; Sukanya Arunachalam; Di Huang; Natasha Vallis; Michael J. Collins; Fred K. Chen
TAGS: deep learning, optical coherence tomography, stargardt's disease, training, volume, pixel
Trans. Vis. Sci. Tech.. 2020; 9(11):12. doi: https://doi.org/10.1167/tvst.9.11.12

Includes: Supplemental Content

Articles October 2020

Mitochondrial Transfer of the Mutant Human ND6T14484C Gene Causes Visual Loss and Optic Neuropathy

PDF

Hong Yu; David W. Sant; Gaofeng Wang; John Guy
TAGS: blindness, genes, mice, mitochondrial donation, optic atrophy, hereditary, leber, optic nerve disorders, carrying, injections
Trans. Vis. Sci. Tech.. 2020; 9(11):1. doi: https://doi.org/10.1167/tvst.9.11.1

Includes: Supplemental Content

Articles September 2020

Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) in Patients with Choroideremia

PDF

Alexandra S. Vitale; Lydia Sauer; Natalie K. Modersitzki; Paul S. Bernstein
TAGS: choroideremia, diagnostic imaging, fluorescence, ophthalmoscopy, eye, follow-up, atrophy
Trans. Vis. Sci. Tech.. 2020; 9(10):33. doi: https://doi.org/10.1167/tvst.9.10.33

Articles September 2020

Plasma Biomarkers of Reticular Pseudodrusen and the Risk of Progression to Advanced Age-Related Macular Degeneration

PDF

Anne M. Lynch; Brandie D. Wagner; Alan G. Palestine; Nebojsa Janjic; Jennifer L. Patnaik; Marc T. Mathias; Frank S. Siringo; Naresh Mandava
TAGS: age-related macular degeneration, biological markers, plasma, proteins, proteomics, reticular pseudodrusen
Trans. Vis. Sci. Tech.. 2020; 9(10):12. doi: https://doi.org/10.1167/tvst.9.10.12

Includes: Supplemental Content

Articles September 2020

Longitudinal Changes of Macular Curvature in Patients with Retinitis Pigmentosa

PDF

Monika Meinert; Shinji Ueno; Shiori Komori; Yoshito Koyanagi; Akira Sayo; Sten Andreasson; Taro Kominami; Yasuki Ito; Hiroko Terasaki
TAGS: eye, millon clinical multiaxial inventory, retinitis pigmentosa, shape, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2020; 9(10):11. doi: https://doi.org/10.1167/tvst.9.10.11

Special Issue September 2020

Piloting a Deep Learning Model for Predicting Nuclear BAP1 Immunohistochemical Expression of Uveal Melanoma from Hematoxylin-and-Eosin Sections

PDF

Hongrun Zhang; Helen Kalirai; Amelia Acha-Sagredo; Xiaoyun Yang; Yalin Zheng; Sarah E. Coupland
TAGS: bap1 gene, deep learning, eosine yellowish-(ys), hematoxylin, intraocular melanoma, neoplasms, training
Trans. Vis. Sci. Tech.. 2020; 9(2):50. doi: https://doi.org/10.1167/tvst.9.2.50

Includes: Supplemental Content

Articles August 2020

Trinucleotide Repeat-Targeting dCas9 as a Therapeutic Strategy for Fuchs’ Endothelial Corneal Dystrophy

PDF

Ziye Rong; Xin Gong; John D. Hulleman; David R. Corey; V. Vinod Mootha
TAGS: endothelium, hereditary corneal dystrophy, rna, dna, endothelial cells
Trans. Vis. Sci. Tech.. 2020; 9(9):47. doi: https://doi.org/10.1167/tvst.9.9.47

Includes: Supplemental Content

Articles August 2020

Integrating Differential Gene Expression Analysis with Perturbagen-Response Signatures May Identify Novel Therapies for Thyroid-Associated Orbitopathy

PDF

John Y. Lee; Ryan A. Gallo; Paul J. Ledon; Wensi Tao; David T. Tse; Daniel Pelaez; Sara T. Wester
TAGS: gene expression, molecule, thyroid, adipocytes, genes, mitoxantrone, small molecule
Trans. Vis. Sci. Tech.. 2020; 9(9):39. doi: https://doi.org/10.1167/tvst.9.9.39

Includes: Supplemental Content

Articles August 2020

Functional Analysis of Rare Genetic Variants in Complement Factor I ( CFI ) using a Serum-Based Assay in Advanced Age-related Macular Degeneration

PDF

Anuja Java; Peter Baciu; Rafael Widjajahakim; Yun Ju Sung; Jae Yang; David Kavanagh; John Atkinson; Johanna Seddon
TAGS: age-related macular degeneration, complement factor i, cultural formulation interview, fibrinogen, genetics, inactivated c3b
Trans. Vis. Sci. Tech.. 2020; 9(9):37. doi: https://doi.org/10.1167/tvst.9.9.37

Includes: Supplemental Content

Articles August 2020

Electrophysiological and Pupillometric Abnormalities in PROM1 Cone–Rod Dystrophy

PDF

Jason C. Park; Frederick T. Collison; Gerald A. Fishman; J. Jason McAnany
TAGS: electroretinography, passive leg raising, progressive cone-rod dystrophy, retinitis pigmentosa, luminance
Trans. Vis. Sci. Tech.. 2020; 9(9):26. doi: https://doi.org/10.1167/tvst.9.9.26

Articles August 2020

Cost Effectiveness of Voretigene Neparvovec for RPE65-Mediated Inherited Retinal Degeneration in Germany

PDF

Matthias Fritz Uhrmann; Birgit Lorenz; Christian Gissel
TAGS: cost effectiveness, germany, retinal degeneration, rpe65 protein, voretigene neparvovec, quality-adjusted life years
Trans. Vis. Sci. Tech.. 2020; 9(9):17. doi: https://doi.org/10.1167/tvst.9.9.17

Articles August 2020

Development of a Quantitative Immunoassay for Tear Lacritin Proteoforms

PDF

Brooke M. Justis; Casey E. Coburn; Ethan M. Tyler; Ryan S. Showalter; Brianna J. Dissler; Melissa Li; Nancy A. McNamara; Gordon W. Laurie; Robert L. McKown
TAGS: antibodies, immunoassay, proteins, schirmer tear test procedure, protein measurement, total, western blotting, recovery of function, volume
Trans. Vis. Sci. Tech.. 2020; 9(9):13. doi: https://doi.org/10.1167/tvst.9.9.13

Articles August 2020

Retinal and Choroidal Vasculature in Patients with Marfan Syndrome

PDF

Matteo Di Marino; Massimo Cesareo; Gianluca Aloe; Carlo Nucci; Clarissa Giannini; Alessio Martucci; Francesco Aiello; Calogera Pisano; Giovanni Ruvolo; Raffaele Mancino
TAGS: marfan syndrome, retinal vasculature, vasculature
Trans. Vis. Sci. Tech.. 2020; 9(9):5. doi: https://doi.org/10.1167/tvst.9.9.5

Articles July 2020

Filamentous Fungal Keratitis in Taiwan: Based on Molecular Diagnosis

PDF

Ning Hung; Lung-Kun Yeh; David Hui-Kang Ma; Hsin-Chiung Lin; Hsin-Yuan Tan; Hung-Chi Chen; Pei-Lun Sun; Ching-Hsi Hsiao
TAGS: fungal keratitis, molecular diagnostic techniques, taiwan, disease susceptibility
Trans. Vis. Sci. Tech.. 2020; 9(8):32. doi: https://doi.org/10.1167/tvst.9.8.32

New Developments in Vision Research July 2020

Report from a Workshop on Accelerating the Development of Treatments for Inherited Retinal Dystrophies Associated with Mutations in the RDH12 Gene

PDF

Francesca Sofia; Silvia Cerolini; Todd Durham
TAGS: blindness, family, genes, hereditary retinal dystrophy, mutation, natural history, gene therapy, retina, retinal dystrophies, disease progression
Trans. Vis. Sci. Tech.. 2020; 9(8):30. doi: https://doi.org/10.1167/tvst.9.8.30

Includes: Supplemental Content

Special Issue July 2020

Cone Identification in Choroideremia: Repeatability, Reliability, and Automation Through Use of a Convolutional Neural Network

PDF

Jessica I. W. Morgan; Min Chen; Andrew M. Huang; Yu You Jiang; Robert F. Cooper
TAGS: choroideremia, convolutional neural networks, reliability, retinal cone
Trans. Vis. Sci. Tech.. 2020; 9(2):40. doi: https://doi.org/10.1167/tvst.9.2.40

1 2 3 4 5

Next 20 Results »

NARROW

Content Type

Journal

Article Type

Topics

Tags

Filters

Specify Date Range

Laser Capture Microdissection-Based RNA Microsequencing Reveals Optic Nerve Crush-Related Early mRNA Alterations in Retinal Ganglion Cell Layer

Artificial Intelligence for Automated Overlay of Fundus Camera and Scanning Laser Ophthalmoscope Images

Protein Composition of the Subretinal Fluid Suggests Selective Diffusion of Vitreous Proteins in Retinal Detachment

Transgenic Expression of Cacna1f Rescues Vision and Retinal Morphology in a Mouse Model of Congenital Stationary Night Blindness 2A (CSNB2A)

Retinal Boundary Segmentation in Stargardt Disease Optical Coherence Tomography Images Using Automated Deep Learning

Mitochondrial Transfer of the Mutant Human ND6T14484C Gene Causes Visual Loss and Optic Neuropathy

Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) in Patients with Choroideremia

Plasma Biomarkers of Reticular Pseudodrusen and the Risk of Progression to Advanced Age-Related Macular Degeneration

Longitudinal Changes of Macular Curvature in Patients with Retinitis Pigmentosa

Piloting a Deep Learning Model for Predicting Nuclear BAP1 Immunohistochemical Expression of Uveal Melanoma from Hematoxylin-and-Eosin Sections

Trinucleotide Repeat-Targeting dCas9 as a Therapeutic Strategy for Fuchs’ Endothelial Corneal Dystrophy

Integrating Differential Gene Expression Analysis with Perturbagen-Response Signatures May Identify Novel Therapies for Thyroid-Associated Orbitopathy

Functional Analysis of Rare Genetic Variants in Complement Factor I ( CFI ) using a Serum-Based Assay in Advanced Age-related Macular Degeneration

Electrophysiological and Pupillometric Abnormalities in PROM1 Cone–Rod Dystrophy

Cost Effectiveness of Voretigene Neparvovec for RPE65-Mediated Inherited Retinal Degeneration in Germany

Development of a Quantitative Immunoassay for Tear Lacritin Proteoforms

Retinal and Choroidal Vasculature in Patients with Marfan Syndrome

Filamentous Fungal Keratitis in Taiwan: Based on Molecular Diagnosis

Report from a Workshop on Accelerating the Development of Treatments for Inherited Retinal Dystrophies Associated with Mutations in the RDH12 Gene

Cone Identification in Choroideremia: Repeatability, Reliability, and Automation Through Use of a Convolutional Neural Network

This feature is available to authenticated users only.

Genetics

To View More...

You must be signed into an individual account to use this feature.