Genetics

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Articles February 2019

A Novel Method for the Objective Identification of Hyperautofluorescent Ring in Retinitis Pigmentosa Using Binarization Processing

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Yohei Hashimoto; Tatsuya Inoue; Takashi Ono; Jinhee Lee; Saori Tsuneyoshi; Asahi Fujita; Yuji Inoue; Shun Ogawa; Ryo Asaoka; Ryo Obata
TAGS: retinitis pigmentosa
Trans. Vis. Sci. Tech.. 2019; 8(1):20. doi: 10.1167/tvst.8.1.20

Articles January 2019

Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

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Joseph D. Bogaard; Jonathon B. Young; Asad Movahedan; Iris S. Kassem
TAGS: enoxaparin, child, animal model, triamcinolone, eye, fibrin, therapeutic intervention, oryctolagus cuniculus, postoperative care, anterior chamber of eye, inflammation, enzyme-linked immunosorbent assay, did not receive therapy or drug
Trans. Vis. Sci. Tech.. 2019; 8(1):5. doi: 10.1167/tvst.8.1.5

Articles December 2018

A Model to Study Thermal Energy Delivery to the Choroid: A Comparison of Surgical Devices

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Stephen A. LoBue; Prashant Tailor; Jarel K. Gandhi; Paul Loftness; Timothy W. Olsen
TAGS: heat (physical force), surgical procedures, operative, body tissue, body temperature, choroid, mpl gene, temperature
Trans. Vis. Sci. Tech.. 2018; 7(6):39. doi: 10.1167/tvst.7.6.39

Articles December 2018

A New in Vitro Model of GDLD by Knocking Out TACSTD2 and Its Paralogous Gene EpCAM in Human Corneal Epithelial Cells

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Peng Xu; Chifune Kai; Satoshi Kawasaki; Yuki Kobayashi; Kouji Yamamoto; Motokazu Tsujikawa; Ryuhei Hayashi; Kohji Nishida
TAGS: proteins, epcam gene, corneal epithelial cells, antibodies, epithelial cell adhesion molecule, genes, epithelium, cornea
Trans. Vis. Sci. Tech.. 2018; 7(6):30. doi: 10.1167/tvst.7.6.30

Articles December 2018

Retinal Toxicity of Intravitreal Injection of Ziv-Aflibercept in Albino Rabbits

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Dan Ramon; Jonathan Shahar; Amir Massarweh; Irit Man; Ido Perlman; Anat Loewenstein
TAGS: albinism, glial fibrillary acidic protein, eye, retina, retinal toxicity, intravitreal injections, ziv-aflibercept, electroretinography, oryctolagus cuniculus
Trans. Vis. Sci. Tech.. 2018; 7(6):23. doi: 10.1167/tvst.7.6.23

Articles December 2018

Combined Targeted Analysis of Metabolites and Proteins in Tear Fluid With Regard to Clinical Applications

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Sascha Dammeier; Peter Martus; Franziska Klose; Michael Seid; Dario Bosch; Janina D‘Alvise; Focke Ziemssen; Spyridon Dimopoulos; Marius Ueffing
TAGS: eye, proteins, metabolites
Trans. Vis. Sci. Tech.. 2018; 7(6):22. doi: 10.1167/tvst.7.6.22

Includes: Supplemental Content

Articles November 2018

Intravitreal Trimethoprim and Sulfamethoxazole Toxicity to the Retina of Albino Rabbits

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Orit Mazza; Zohar Habot-Wilner; Jonathan Shahar; Irit Mann; Anat Loewenstein; Ido Perlman
TAGS: albinism, electroretinography, evoked potentials, visual, follow-up, oryctolagus cuniculus, sulfamethoxazole, trimethoprim, trimethoprim-sulfamethoxazole combination, eye, retina, toxic effect, intravitreal injections
Trans. Vis. Sci. Tech.. 2018; 7(6):2. doi: 10.1167/tvst.7.6.2

Articles October 2018

Matrix Metalloproteinase 9 Point-of-Care Immunoassay Result Predicts Response to Topical Cyclosporine Treatment in Dry Eye Disease

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Jae Yong Park; Bum Gi Kim; Jae Suk Kim; Je Hyung Hwang
TAGS: dry eye syndromes, gelatinase b, immunoassay, cyclosporine
Trans. Vis. Sci. Tech.. 2018; 7(5):31. doi: 10.1167/tvst.7.5.31

Articles October 2018

Development and Validation of the Singapore Thyroid Eye Disease Quality of Life Questionnaire

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Melissa H. Y. Wong; Eva Fenwick; Ai Tee Aw; Ecosse L. Lamoureux; Lay Leng Seah
TAGS: graves' ophthalmopathy, psychometrics, questionnaires, singapore, quality of life
Trans. Vis. Sci. Tech.. 2018; 7(5):14. doi: 10.1167/tvst.7.5.14

Includes: Supplemental Content

Review September 2018

Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease

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Gabriel Velez; Peter H. Tang; Thiago Cabral; Galaxy Y. Cho; Daniel A. Machlab; Stephen H. Tsang; Alexander G. Bassuk; Vinit B. Mahajan
TAGS: biological markers, health, body tissue, vitreous body, eye, proteins, proteomics, vitreoretinal disease, precision
Trans. Vis. Sci. Tech.. 2018; 7(5):12. doi: 10.1167/tvst.7.5.12

New Developments in Vision Research September 2018

Translational Retinal Research and Therapies

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Alison J. Hardcastle; Paul A. Sieving; José-Alain Sahel; Samuel G. Jacobson; Artur V. Cideciyan; John G. Flannery; William A. Beltran; Gustavo D. Aguirre
TAGS: gene therapy, mutation, blindness, retinal cone, dog, domestic, genes, genome, animal model, photoreceptors, retinal degeneration, retinitis pigmentosa, rhodopsin, rod photoreceptors, vision, mice, proteins, retina, leber's amaurosis, spatial vectors, optogenetics
Trans. Vis. Sci. Tech.. 2018; 7(5):8. doi: 10.1167/tvst.7.5.8

Articles September 2018

Imaging Melanin Distribution in the Zebrafish Retina Using Photothermal Optical Coherence Tomography

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Maryse Lapierre-Landry; Alison L. Huckenpahler; Brian A. Link; Ross F. Collery; Joseph Carroll; Melissa C. Skala
TAGS: melanins, zebrafish, diagnostic imaging, eye, mosaicism, retina, optical coherence tomography
Trans. Vis. Sci. Tech.. 2018; 7(5):4. doi: 10.1167/tvst.7.5.4

Perspective July 2018

Inherited Retinal Degenerations: Current Landscape and Knowledge Gaps

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Jacque L. Duncan; Eric A. Pierce; Amy M. Laster; Stephen P. Daiger; David G. Birch; John D. Ash; Alessandro Iannaccone; John G. Flannery; José A. Sahel; Donald J. Zack; Marco A. Zarbin; and the Foundation Fighting Blindness Scientific Advisory Board
TAGS: mutation, genetics, genes, animal model, retinal degeneration, comprehension
Trans. Vis. Sci. Tech.. 2018; 7(4):6. doi: 10.1167/tvst.7.4.6

Articles June 2018

Intraobserver Repeatability and Interobserver Reproducibility of Ellipsoid Zone Measurements in Retinitis Pigmentosa

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Margaret R. Strampe; Alison L. Huckenpahler; Brian P. Higgins; Sergey Tarima; Alexis Visotcky; Kimberly E. Stepien; Christine N. Kay; Joseph Carroll
TAGS: retinitis pigmentosa, usher syndrome, spectral-domain optical coherence tomography
Trans. Vis. Sci. Tech.. 2018; 7(3):13. doi: 10.1167/tvst.7.3.13

Includes: Multimedia, Supplemental Content

Articles April 2018

Sub-Airy Confocal Adaptive Optics Scanning Ophthalmoscopy

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Nripun Sredar; Oladipo E. Fagbemi; Alfredo Dubra
TAGS: retinal cone, ophthalmoscopes, ophthalmoscopy, optics, eye, miosis disorder, pupil constriction, mosaicism
Trans. Vis. Sci. Tech.. 2018; 7(2):17. doi: 10.1167/tvst.7.2.17

Articles December 2017

Differential Gene Transcription of Extracellular Matrix Components in Response to In Vivo Corneal Crosslinking (CXL) in Rabbit Corneas

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Sabine Kling; Arthur Hammer; Emilio A. Torres Netto; Farhad Hafezi
TAGS: transcription, genetic, extracellular matrix, genes, oryctolagus cuniculus, cornea, corneal collagen cross-linking
Trans. Vis. Sci. Tech.. 2017; 6(6):8. doi: 10.1167/tvst.6.6.8

Includes: Supplemental Content

Review September 2017

Restoration of Cone Photoreceptor Function in Retinitis Pigmentosa

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Henry J. Kaplan; Wei Wang; Douglas C. Dean
TAGS: retinal cone, retinitis pigmentosa
Trans. Vis. Sci. Tech.. 2017; 6(5):5. doi: 10.1167/tvst.6.5.5

Articles July 2017

Retinal Pigment Epithelial Cells are a Potential Reservoir for Ebola Virus in the Human Eye

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Justine R. Smith; Shawn Todd; Liam M. Ashander; Theodosia Charitou; Yuefang Ma; Steven Yeh; Ian Crozier; Michael Z. Michael; Binoy Appukuttan; Keryn A. Williams; David J. Lynn; Glenn A. Marsh
TAGS: ebola virus, infection, eye, retinal pigment cell
Trans. Vis. Sci. Tech.. 2017; 6(4):12. doi: 10.1167/tvst.6.4.12

Includes: Supplemental Content

Articles July 2017

Impact of Vital Dyes on Cell Viability and Transduction Efficiency of AAV Vectors Used in Retinal Gene Therapy Surgery: An In Vitro and In Vivo Analysis

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Anna P. Salvetti; Maria I. Patrício; Alun R. Barnard; Harry O. Orlans; Doron G. Hickey; Robert E. MacLaren
TAGS: gene therapy, cell survival, dyes, injection of therapeutic agent, surgical procedures, operative, toxic effect, spatial vectors
Trans. Vis. Sci. Tech.. 2017; 6(4):4. doi: 10.1167/tvst.6.4.4

Includes: Supplemental Content

Articles July 2017

Light Modulates Ocular Complications in an Albino Rat Model of Type 1 Diabetes Mellitus

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Elias Andrawus; Gizi Veildbaum; Esther Zemel; Rina Leibu; Ido Perlman; Naim Shehadeh
TAGS: diabetes mellitus, albinism, diabetes mellitus, type 1, cataract, electroretinography, glial fibrillary acidic protein, rats, immunocytochemistry, white light, ocular complications
Trans. Vis. Sci. Tech.. 2017; 6(4):1. doi: 10.1167/tvst.6.4.1

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A Novel Method for the Objective Identification of Hyperautofluorescent Ring in Retinitis Pigmentosa Using Binarization Processing

Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

A Model to Study Thermal Energy Delivery to the Choroid: A Comparison of Surgical Devices

A New in Vitro Model of GDLD by Knocking Out TACSTD2 and Its Paralogous Gene EpCAM in Human Corneal Epithelial Cells

Retinal Toxicity of Intravitreal Injection of Ziv-Aflibercept in Albino Rabbits

Combined Targeted Analysis of Metabolites and Proteins in Tear Fluid With Regard to Clinical Applications

Intravitreal Trimethoprim and Sulfamethoxazole Toxicity to the Retina of Albino Rabbits

Matrix Metalloproteinase 9 Point-of-Care Immunoassay Result Predicts Response to Topical Cyclosporine Treatment in Dry Eye Disease

Development and Validation of the Singapore Thyroid Eye Disease Quality of Life Questionnaire

Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease

Translational Retinal Research and Therapies

Imaging Melanin Distribution in the Zebrafish Retina Using Photothermal Optical Coherence Tomography

Inherited Retinal Degenerations: Current Landscape and Knowledge Gaps

Intraobserver Repeatability and Interobserver Reproducibility of Ellipsoid Zone Measurements in Retinitis Pigmentosa

Sub-Airy Confocal Adaptive Optics Scanning Ophthalmoscopy

Differential Gene Transcription of Extracellular Matrix Components in Response to In Vivo Corneal Crosslinking (CXL) in Rabbit Corneas

Restoration of Cone Photoreceptor Function in Retinitis Pigmentosa

Retinal Pigment Epithelial Cells are a Potential Reservoir for Ebola Virus in the Human Eye

Impact of Vital Dyes on Cell Viability and Transduction Efficiency of AAV Vectors Used in Retinal Gene Therapy Surgery: An In Vitro and In Vivo Analysis

Light Modulates Ocular Complications in an Albino Rat Model of Type 1 Diabetes Mellitus

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