Glaucoma

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Glaucoma October 2019

Association of Corneal Hysteresis With Lamina Cribrosa Curvature in Primary Open Angle Glaucoma

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Kyoung Min Lee; Tae-Woo Kim; Eun Ji Lee; Michaël J. A. Girard; Jean Martial Mari; Robert N. Weinreb
TAGS: cornea, corneal hysteresis, cribriform plate, genu varum, open-angle glaucoma, eye, glaucoma, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4171-4177. doi: 10.1167/iovs.19-27087

Includes: Supplemental Content

Glaucoma October 2019

The Relationship Between Scleral Strain Change and Differential Cumulative Intraocular Pressure Exposure in the Nonhuman Primate Chronic Ocular Hypertension Model

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Massimo A. Fazio; Michael J. A. Girard; Wonyul Lee; Jeffrey S. Morris; Claude F. Burgoyne; J. Crawford Downs
TAGS: eye, intraocular pressure, ocular hypertension, sclera, primates
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4141-4150. doi: 10.1167/iovs.19-27060

Articles October 2019

Imaging Distal Aqueous Outflow Pathways in a Spontaneous Model of Congenital Glaucoma

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Kevin C. Snyder; Kazuya Oikawa; Jeremy Williams; Julie A. Kiland; Shaile Gehrke; Leandro B. C. Teixeira; Alex S. Huang; Gillian J. McLellan
TAGS: angiogram, cats, diagnostic imaging, eye, glaucoma, glaucoma, congenital, sclera, spectral-domain optical coherence tomography, body tissue
Trans. Vis. Sci. Tech.. 2019; 8(5):22. doi: 10.1167/tvst.8.5.22

Includes: Supplemental Content

Articles October 2019

Mobility-Related Gaze Training in Individuals With Glaucoma: A Proof-of-Concept Study

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Shaila M. Gunn; Kim Lajoie; Kim T. Zebehazy; Robert A. Strath; David R. Neima; Daniel S. Marigold
TAGS: gait, gaze, glaucoma, mobility, training, proof of concept studies
Trans. Vis. Sci. Tech.. 2019; 8(5):23. doi: 10.1167/tvst.8.5.23

Physiology and Pharmacology October 2019

Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow

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Evan A. Thackaberry; Yi Zhou; Christina L. Zuch de Zafra; Germaine Fuh; Chingwei V. Lee; Sarah Sanowar; John B. Ridgway; Aija M. Kusi; Cindy Farman; Helen Booler; Daniel Sheinson; Carol A. Rasmussen; Paul E. Miller; Eric Wakshull; Minhong Yan; Vladimir Bantseev
TAGS: antibodies, anti-vascular endothelial growth factor therapy, aqueous humor, eye, glaucoma, intraocular pressure, macaca fascicularis, primates, signal transduction, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4097-4108. doi: 10.1167/iovs.18-26349

Glaucoma September 2019

NOS3 Deletion in Cav1 Deficient Mice Decreases Drug Sensitivity to a Nitric Oxide Donor and Two Nitric Oxide Synthase Inhibitors

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Maomao Song; Liping Li; Yuan Lei; Xinghuai Sun
TAGS: donors, intraocular pressure, mice, nitric oxide, nitric oxide synthase, nitric oxide synthase inhibitors, cyclic gmp, ng-nitroarginine methyl ester, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4002-4007. doi: 10.1167/iovs.19-27582

Includes: Supplemental Content

Retina September 2019

Longitudinal Changes in the Peripapillary Retinal Nerve Fiber Layer Thickness in Hypertension: 4-Year Prospective Observational Study

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Min-Woo Lee; Woo-Hyuk Lee; Gi-Seok Park; Hyung-Bin Lim; Jung-Yeul Kim
TAGS: hypertension, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3914-3919. doi: 10.1167/iovs.19-27652

Glaucoma September 2019

Activation of αvβ3 Integrin Alters Fibronectin Fibril Formation in Human Trabecular Meshwork Cells in a ROCK-Independent Manner

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Mark S. Filla; Jennifer A. Faralli; Harini Desikan; Jennifer L. Peotter; Abigail C. Wannow; Donna M. Peters
TAGS: fibril, fibronectins, integrins
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3897-3913. doi: 10.1167/iovs.19-27171

Includes: Supplemental Content

Clinical and Epidemiologic Research September 2019

Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates

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Jessica V. Jasien; Christopher A. Girkin; J. Crawford Downs
TAGS: intraocular pressure, primates, telemetry, wireless technology, ketamine, dexmedetomidine, xylazine
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3830-3834. doi: 10.1167/iovs.19-27758

Glaucoma September 2019

Reversibility of Retinal Ganglion Cell Dysfunction From Chronic IOP Elevation

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Da Zhao; Vickie H. Y. Wong; Christine T. O. Nguyen; Andrew I. Jobling; Erica L. Fletcher; Algis J. Vingrys; Bang V. Bui
TAGS: ganglia, intraocular pressure, pathophysiology, recovery of function, retinal ganglion cells, electroretinography, eye, sutures, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3878-3886. doi: 10.1167/iovs.19-27113

Includes: Supplemental Content

Articles September 2019

Δ 9 -Tetrahydrocannabinol Derivative-Loaded Nanoformulation Lowers Intraocular Pressure in Normotensive Rabbits

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Pranjal S. Taskar; Akash Patil; Prit Lakhani; Eman Ashour; Waseem Gul; Mahmoud A. ElSohly; Brian Murphy; Soumyajit Majumdar
TAGS: tetrahydrocannabinol, intraocular pressure, oryctolagus cuniculus
Trans. Vis. Sci. Tech.. 2019; 8(5):15. doi: 10.1167/tvst.8.5.15

Glaucoma September 2019

Fixel-Based Analysis of Visual Pathway White Matter in Primary Open-Angle Glaucoma

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Shereif Haykal; Branislava Ćurčić-Blake; Nomdo M. Jansonius; Frans W. Cornelissen
TAGS: glaucoma, open-angle glaucoma, visual pathways, white matter, otosclerosis, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3803-3812. doi: 10.1167/iovs.19-27447

Includes: Supplemental Content

Articles September 2019

Characterization of Corneal Biomechanical Properties and Determination of Natural Intraocular Pressure Using CID-GAT

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Shu-Hao Lu; I. T. Chong; Stanley Y. Y. Leung; David C. C. Lam
TAGS: collision-induced dissociation, cornea, intraocular pressure, eye
Trans. Vis. Sci. Tech.. 2019; 8(5):10. doi: 10.1167/tvst.8.5.10

Articles September 2019

Comparison of Methods to Detect and Measure Glaucomatous Visual Field Progression

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Alessandro Rabiolo; Esteban Morales; Lilian Mohamed; Vicente Capistrano; Ji Hyun Kim; Abdelmonem Afifi; Fei Yu; Anne L. Coleman; Kouros Nouri-Mahdavi; Joseph Caprioli
TAGS: glaucoma, visual fields, cohort studies
Trans. Vis. Sci. Tech.. 2019; 8(5):2. doi: 10.1167/tvst.8.5.2

Glaucoma September 2019

Peripapillary Choroidal Vascularity Index and Microstructure of Parapapillary Atrophy

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Min Hee Suh; Jun Woo Park; Neha Khandelwal; Rupesh Agrawal
TAGS: atrophy, cortical blindness, antidepressive agents, tricyclic, trichloroacetic acid, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3768-3775. doi: 10.1167/iovs.18-26286

Retinal Cell Biology September 2019

Survival of Alpha and Intrinsically Photosensitive Retinal Ganglion Cells in NMDA-Induced Neurotoxicity and a Mouse Model of Normal Tension Glaucoma

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Sari Honda; Kazuhiko Namekata; Atsuko Kimura; Xiaoli Guo; Chikako Harada; Akira Murakami; Akira Matsuda; Takayuki Harada
TAGS: glaucoma, glaucoma, normal-tension, melanopsin, mice, neurotoxicity syndromes, n-methylaspartate, retina, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3696-3707. doi: 10.1167/iovs.19-27145

Includes: Supplemental Content

Glaucoma August 2019

Physiologic Electrical Fields Direct Retinal Ganglion Cell Axon Growth In Vitro

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Kimberly K. Gokoffski; Xingyuan Jia; Daniel Shvarts; Guohua Xia; Min Zhao
TAGS: axon, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3659-3668. doi: 10.1167/iovs.18-25118

Includes: Multimedia, Supplemental Content

Glaucoma August 2019

Glaucoma-Associated Mutations in the Optineurin Gene Have Limited Impact on Parkin-Dependent Mitophagy

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Kseniia Chernyshova; Keiichi Inoue; Shun-Ichi Yamashita; Takeo Fukuchi; Tomotake Kanki
TAGS: glaucoma, mutation, optn gene, park2 gene, proteins, genes, ubiquitin, carbonyl cyanide m-chlorophenyl hydrazone, mitochondria
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3625-3635. doi: 10.1167/iovs.19-27184

Includes: Supplemental Content

Glaucoma August 2019

Mitochondrial-Targeted Antioxidants Attenuate TGF-β2 Signaling in Human Trabecular Meshwork Cells

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Vidhya R. Rao; Jonathan D. Lautz; Simon Kaja; Eileen M. Foecking; Emőke Lukács; Evan B. Stubbs, Jr
TAGS: antioxidants, attenuation, mitochondria, signal transduction, trabecular meshwork
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3613-3624. doi: 10.1167/iovs.19-27542

Articles August 2019

Correlation Between the Myopic Retinal Deformation and Corneal Biomechanical Characteristics Measured With the Corvis ST Tonometry

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Shotaro Asano; Ryo Asaoka; Takehiro Yamashita; Shuichiro Aoki; Masato Matsuura; Yuri Fujino; Hiroshi Murata; Shunsuke Nakakura; Yoshitaka Nakao; Yoshiaki Kiuchi
TAGS: cornea, tonometry, refractive errors, eye
Trans. Vis. Sci. Tech.. 2019; 8(4):26. doi: 10.1167/tvst.8.4.26

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Association of Corneal Hysteresis With Lamina Cribrosa Curvature in Primary Open Angle Glaucoma

The Relationship Between Scleral Strain Change and Differential Cumulative Intraocular Pressure Exposure in the Nonhuman Primate Chronic Ocular Hypertension Model

Imaging Distal Aqueous Outflow Pathways in a Spontaneous Model of Congenital Glaucoma

Mobility-Related Gaze Training in Individuals With Glaucoma: A Proof-of-Concept Study

Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow

NOS3 Deletion in Cav1 Deficient Mice Decreases Drug Sensitivity to a Nitric Oxide Donor and Two Nitric Oxide Synthase Inhibitors

Longitudinal Changes in the Peripapillary Retinal Nerve Fiber Layer Thickness in Hypertension: 4-Year Prospective Observational Study

Activation of αvβ3 Integrin Alters Fibronectin Fibril Formation in Human Trabecular Meshwork Cells in a ROCK-Independent Manner

Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates

Reversibility of Retinal Ganglion Cell Dysfunction From Chronic IOP Elevation

Δ 9 -Tetrahydrocannabinol Derivative-Loaded Nanoformulation Lowers Intraocular Pressure in Normotensive Rabbits

Fixel-Based Analysis of Visual Pathway White Matter in Primary Open-Angle Glaucoma

Characterization of Corneal Biomechanical Properties and Determination of Natural Intraocular Pressure Using CID-GAT

Comparison of Methods to Detect and Measure Glaucomatous Visual Field Progression

Peripapillary Choroidal Vascularity Index and Microstructure of Parapapillary Atrophy

Survival of Alpha and Intrinsically Photosensitive Retinal Ganglion Cells in NMDA-Induced Neurotoxicity and a Mouse Model of Normal Tension Glaucoma

Physiologic Electrical Fields Direct Retinal Ganglion Cell Axon Growth In Vitro

Glaucoma-Associated Mutations in the Optineurin Gene Have Limited Impact on Parkin-Dependent Mitophagy

Mitochondrial-Targeted Antioxidants Attenuate TGF-β2 Signaling in Human Trabecular Meshwork Cells

Correlation Between the Myopic Retinal Deformation and Corneal Biomechanical Characteristics Measured With the Corvis ST Tonometry

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