Glaucoma

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Glaucoma September 2021

Binocular Interactions in Glaucoma Patients With Nonoverlapping Visual Field Defects: Contrast Summation, Rivalry, and Phase Combination

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Catarina A. R. João; Lorenzo Scanferla; Nomdo M. Jansonius
TAGS: eye, glaucoma, summation, vision, visual field defects
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):9. doi: https://doi.org/10.1167/iovs.62.12.9

Glaucoma September 2021

Using CRISPR Interference as a Therapeutic Approach to Treat TGFβ2-Induced Ocular Hypertension and Glaucoma

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Naga Pradeep Rayana; Chenna Kesavulu Sugali; Jiannong Dai; Michael Peng; Shaohui Liu; Yucheng Zhang; Jun Wan; Weiming Mao
TAGS: crispr, eye, glaucoma, mice, ocular hypertension, cytomegalovirus, lentiviral vector, adenoviruses, genes
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):7. doi: https://doi.org/10.1167/iovs.62.12.7

Includes: Supplemental Content

Glaucoma September 2021

U-Shaped Effect of Blood Pressure on Structural OCT Metrics and Retinal Perfusion in Ophthalmologically Healthy Subjects

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Konstantinos Pappelis; Nomdo M. Jansonius
TAGS: blood pressure, glaucoma, homeostasis, hypotension, perfusion, vascular flow, ventricular rate rapid, mediation analysis, hypertension, did not receive therapy or drug
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):5. doi: https://doi.org/10.1167/iovs.62.12.5

Includes: Supplemental Content

Glaucoma September 2021

The Relationship Between Optic Disc and Retinal Artery Position and Glaucomatous Visual Field Progression

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Yuri Fujino; Ryo Asaoka; Hiroshi Murata; Takehiro Yamashita
TAGS: central retinal artery, glaucoma, intraocular pressure, optic disk, retina, visual fields, maximum tolerated dose
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):6. doi: https://doi.org/10.1167/iovs.62.12.6

Articles September 2021

Aqueous Cytokine Levels Are Associated With Progression of Peripheral Anterior Synechiae After Descemet Stripping Automated Endothelial Keratoplasty

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Yuki Kusano; Takefumi Yamaguchi; Sota Nishisako; Takehiro Matsumura; Masaki Fukui; Kazunari Higa; Toshihiro Inoue; Jun Shimazaki
TAGS: cytokine, descemet stripping endothelial keratoplasty, isolated tumor cells, peripheral anterior synechiae, protein measurement, total, eye
Trans. Vis. Sci. Tech.. 2021; 10(11):12. doi: https://doi.org/10.1167/tvst.10.11.12

Includes: Supplemental Content

Glaucoma August 2021

Implications of the Relationship Between Refractive Error and Biometry in the Pathogenesis of Primary Angle Closure

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Kilhwan Shon; Kyung Rim Sung; Joo Young Yoon
TAGS: biometry, eye, pathogenesis, refractive errors, cornea, correlation studies, regression analysis
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):38. doi: https://doi.org/10.1167/iovs.62.10.38

Articles August 2021

A Novel Indentation Assessment to Measure Corneal Biomechanical Properties in Glaucoma and Ocular Hypertension

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Yunzhi Xu; Yiming Ye; Iok Tong Chong; Zidong Chen; Jiangang Xu; Yangfan Yang; Keming Yu; David C. C. Lam; Minbin Yu
TAGS: collision-induced dissociation, cornea, glaucoma, ocular hypertension
Trans. Vis. Sci. Tech.. 2021; 10(9):36. doi: https://doi.org/10.1167/tvst.10.9.36

Includes: Supplemental Content

Glaucoma August 2021

iPSC-Derived Trabecular Meshwork Cells Stimulate Endogenous TM Cell Division Through Gap Junction in a Mouse Model of Glaucoma

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Shangru Sui; Hongxia Yu; Xiangji Wang; Wenyan Wang; Xuejiao Yang; Xiaojing Pan; Qingjun Zhou; Chen Xin; Rong Du; Shen Wu; Jingxue Zhang; Qilong Cao; Ningli Wang; Markus H. Kuehn; Wei Zhu
TAGS: cell growth, connexin 43, gap junction protein, glaucoma, medication therapy management, mice, trabecular meshwork, myoc gene, coculture techniques, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):28. doi: https://doi.org/10.1167/iovs.62.10.28

Includes: Supplemental Content

Glaucoma August 2021

Altered Ocular Fibrillin Microfibril Composition in Mice With a Glaucoma-Causing Mutation of Adamts10

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Hang-Jing Wu; Douglas P. Mortlock; Rachel W. Kuchtey; John Kuchtey
TAGS: fibrillin-2, fibrillins, glaucoma, mice, microfibrils, mutation, fibrillin-1, fluorescent antibody technique
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):26. doi: https://doi.org/10.1167/iovs.62.10.26

Multidisciplinary Ophthalmic Imaging August 2021

Diffusion Tensor Imaging of Visual Pathway Abnormalities in Five Glaucoma Animal Models

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Max K. Colbert; Leon C. Ho; Yolandi van der Merwe; Xiaoling Yang; Gillian J. McLellan; Samuel A. Hurley; Aaron S. Field; Hongmin Yun; Yiqin Du; Ian P. Conner; Carlos Parra; Muneeb A. Faiq; John H. Fingert; Gadi Wollstein; Joel S. Schuman; Kevin C. Chan
TAGS: animal model, glaucoma, visual pathways, diffusion tensor imaging
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):21. doi: https://doi.org/10.1167/iovs.62.10.21

Articles August 2021

Intraocular Pressure Reduction by Femtosecond Laser Created Trabecular Channels in Perfused Human Anterior Segments

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Eric Mikula; Guy Holland; Hadi Srass; Carlos Suarez; James V. Jester; Tibor Juhasz
TAGS: femtosecond pulsed lasers, intraocular pressure, trabecular meshwork, eye, lasers, schlemm's canal, perfusion
Trans. Vis. Sci. Tech.. 2021; 10(9):22. doi: https://doi.org/10.1167/tvst.10.9.22

Retina August 2021

Sigma-1R Protects Retinal Ganglion Cells in Optic Nerve Crush Model for Glaucoma

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Linya Li; Shaoqing He; Yang Liu; Thomas Yorio; Dorette Z. Ellis
TAGS: caspase-3, glaucoma, mice, optic nerve, pentazocine, retinal ganglion cells, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):17. doi: https://doi.org/10.1167/iovs.62.10.17

Articles August 2021

Development of Primary Open Angle Glaucoma-Like Features in a Rhesus Macaque Colony From Southern China

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Louis R. Pasquale; Li Gong; Janey L. Wiggs; Lingzhen Pan; Zhenyan Yang; Mingling Wu; Zunyuan Yang; Dong Feng Chen; Wen Zeng
TAGS: cercopithecidae, glaucoma, macaca mulatta, open-angle glaucoma, intraocular pressure, china
Trans. Vis. Sci. Tech.. 2021; 10(9):20. doi: https://doi.org/10.1167/tvst.10.9.20

Includes: Supplemental Content

Glaucoma August 2021

Comparison of Optic Nerve Head Microvasculature Between Normal-Tension Glaucoma and Nonarteritic Anterior Ischemic Optic Neuropathy

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Ji-Ah Kim; Eun Ji Lee; Tae-Woo Kim; Hee Kyung Yang; Jeong-Min Hwang
TAGS: low tension glaucoma, microvascular network, nonarteritic anterior ischemic optic neuropathy, optic disk, eye
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):15. doi: https://doi.org/10.1167/iovs.62.10.15

Includes: Supplemental Content

Glaucoma August 2021

Increased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression

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Heather M. Schmitt; Rachel L. Fehrman; Margaret E. Maes; Huan Yang; Lian-Wang Guo; Cassandra L. Schlamp; Heather R. Pelzel; Robert W. Nickells
TAGS: apoptosis, disease susceptibility, immunohistochemistry, mice, neurons, plasmids, signal transduction, proteins, caspase-3, histone deacetylase
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):14. doi: https://doi.org/10.1167/iovs.62.10.14

Includes: Supplemental Content

Articles August 2021

Estimating the Severity of Visual Field Damage From Retinal Nerve Fiber Layer Thickness Measurements With Artificial Intelligence

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Xiaoqin Huang; Jian Sun; Juleke Majoor; Koenraad Arndt Vermeer; Hans Lemij; Tobias Elze; Mengyu Wang; Michael Vincent Boland; Louis Robert Pasquale; Vahid Mohammadzadeh; Kouros Nouri-Mahdavi; Chris Johnson; Siamak Yousefi
TAGS: retinal nerve fiber layer, visual fields, glaucoma, artificial intelligence, datasets, eye
Trans. Vis. Sci. Tech.. 2021; 10(9):16. doi: https://doi.org/10.1167/tvst.10.9.16

Clinical and Epidemiologic Research August 2021

Fine Particulate Matter and Age-Related Eye Disease: The Canadian Longitudinal Study on Aging

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Alyssa Grant; Gareth Leung; Marie-Josée Aubin; Marie-Jeanne Kergoat; Gisèle Li; Ellen E. Freeman
TAGS: aging, eye diseases, longitudinal studies, particulate matter, glaucoma, visual impairment, health, intraocular pressure, cataract
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):7. doi: https://doi.org/10.1167/iovs.62.10.7

Articles August 2021

Intraocular Pressure-Lowering Effects of Trabeculectomy Versus MicroShunt Insertion in Rabbit Eyes

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Tomokazu Fujimoto; Kei-Ichi Nakashima; Fumika Watanabe-Kitamura; Takahiro Watanabe; Kenichi Nakamura; Kentaro Maki; Atsushi Shimazaki; Masatomo Kato; Hidenobu Tanihara; Toshihiro Inoue
TAGS: blister, eye, intraocular pressure, oryctolagus cuniculus, trabeculectomy, surgical procedures, operative, conjunctiva
Trans. Vis. Sci. Tech.. 2021; 10(9):9. doi: https://doi.org/10.1167/tvst.10.9.9

Includes: Supplemental Content

Articles August 2021

Real-Time Evaluation of Regional Arterial Stiffening, Resistance, and Ocular Circulation During Systemic Administration of Adrenaline in White Rabbits

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Tetsuya Komatsu; Tomoaki Shiba; Kento Watanabe; Kiyoshi Sakuma; Megumi Aimoto; Yoshinobu Nagasawa; Akira Takahara; Yuichi Hori
TAGS: epinephrine, microcirculation, oryctolagus cuniculus, pulse wave velocity
Trans. Vis. Sci. Tech.. 2021; 10(9):11. doi: https://doi.org/10.1167/tvst.10.9.11

Includes: Supplemental Content

Articles August 2021

Nomograms for Converting Perimetric Sensitivity From Full Threshold and SITA Fast to SITA Standard in Patients With Glaucoma and Healthy Subjects

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Sara Giammaria; Jayme R. Vianna; Yuko Ohno; Aiko Iwase; Balwantray C. Chauhan
TAGS: glaucoma, nomogram, visual field testing
Trans. Vis. Sci. Tech.. 2021; 10(9):2. doi: https://doi.org/10.1167/tvst.10.9.2

Includes: Supplemental Content

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Binocular Interactions in Glaucoma Patients With Nonoverlapping Visual Field Defects: Contrast Summation, Rivalry, and Phase Combination

Using CRISPR Interference as a Therapeutic Approach to Treat TGFβ2-Induced Ocular Hypertension and Glaucoma

U-Shaped Effect of Blood Pressure on Structural OCT Metrics and Retinal Perfusion in Ophthalmologically Healthy Subjects

The Relationship Between Optic Disc and Retinal Artery Position and Glaucomatous Visual Field Progression

Aqueous Cytokine Levels Are Associated With Progression of Peripheral Anterior Synechiae After Descemet Stripping Automated Endothelial Keratoplasty

Implications of the Relationship Between Refractive Error and Biometry in the Pathogenesis of Primary Angle Closure

A Novel Indentation Assessment to Measure Corneal Biomechanical Properties in Glaucoma and Ocular Hypertension

iPSC-Derived Trabecular Meshwork Cells Stimulate Endogenous TM Cell Division Through Gap Junction in a Mouse Model of Glaucoma

Altered Ocular Fibrillin Microfibril Composition in Mice With a Glaucoma-Causing Mutation of Adamts10

Diffusion Tensor Imaging of Visual Pathway Abnormalities in Five Glaucoma Animal Models

Intraocular Pressure Reduction by Femtosecond Laser Created Trabecular Channels in Perfused Human Anterior Segments

Sigma-1R Protects Retinal Ganglion Cells in Optic Nerve Crush Model for Glaucoma

Development of Primary Open Angle Glaucoma-Like Features in a Rhesus Macaque Colony From Southern China

Comparison of Optic Nerve Head Microvasculature Between Normal-Tension Glaucoma and Nonarteritic Anterior Ischemic Optic Neuropathy

Increased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression

Estimating the Severity of Visual Field Damage From Retinal Nerve Fiber Layer Thickness Measurements With Artificial Intelligence

Fine Particulate Matter and Age-Related Eye Disease: The Canadian Longitudinal Study on Aging

Intraocular Pressure-Lowering Effects of Trabeculectomy Versus MicroShunt Insertion in Rabbit Eyes

Real-Time Evaluation of Regional Arterial Stiffening, Resistance, and Ocular Circulation During Systemic Administration of Adrenaline in White Rabbits

Nomograms for Converting Perimetric Sensitivity From Full Threshold and SITA Fast to SITA Standard in Patients With Glaucoma and Healthy Subjects

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