Immunology and Microbiology

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Artificial Intelligence June 2025

Development of Deep Learning Models to Screen Posterior Staphylomas in Highly Myopic Eyes Using UWF-OCT Images

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Yining Wang; Changyu Chen; Ziye Wang; Yijin Wu; Hongshuang Lu; Jianping Xiong; Keigo Sugisawa; Koju Kamoi; Kyoko Ohno-Matsui
TAGS: datasets, deep learning, eye, staphyloma, retina, specialism
Trans. Vis. Sci. Tech.. 2025; 14(6):25. https://doi.org/10.1167/tvst.14.6.25

Includes: Supplemental Content

Neuro-ophthalmology June 2025

Aquaporin-4 Peptide Injection in Mice Induces Retinal and Optic Nerve Alterations That Simulate Those of Neuromyelitis Optica Spectrum Disorder

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Mina Okuda-Arai; Sotaro Mori; Yoshichika Katsura; Shota Miyake; Kenichi Serizawa; Makoto Nakamura
TAGS: immunization, mice, neuromyelitis optica, optic nerve, optic neuritis, peptides, water channels, injections
Trans. Vis. Sci. Tech.. 2025; 14(6):21. https://doi.org/10.1167/tvst.14.6.21

Includes: Supplemental Content

Cornea & External Disease April 2025

A Tear-Based Approach for Rapid Identification of Bacterial Pathogens in Corneal Ulcers Using Nanopore Sequencing

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Mark Dibbs; Mitchelle Matesva; Despoina Theotoka; Christina Jayaraj; Beruk Metiku; Patrick Demkowicz; Jacob S. Heng; Yvonne Wang; Christine Y. Bakhoum; Jessica Chow; Mathieu F. Bakhoum
TAGS: bacteria, corneal ulcer, nanopore sequencing, pathogenic organism, ulcer, eye, cornea
Trans. Vis. Sci. Tech.. 2025; 14(4):19. https://doi.org/10.1167/tvst.14.4.19

Includes: Supplemental Content

Cornea & External Disease April 2025

Causal Relationship Between Common Allergic Diseases and Keratoconus: A Two-Sample Mendelian Randomization Study

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Xiru Yang; Xinyao Yu; Shan Gao; Pinghui Wei; Guoge Han
TAGS: extrinsic asthma, hypersensitivity, keratoconus, mendelian randomization analysis, atopic dermatitis, urticaria
Trans. Vis. Sci. Tech.. 2025; 14(4):14. https://doi.org/10.1167/tvst.14.4.14

Cornea & External Disease April 2025

Metabolic Biomarkers Mediate Allergic Conjunctivitis via Circulating Inflammatory Proteins: Evidence From a Mendelian Randomization Study

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Xiang Cao; Zijiao Xu; Boyang Zhang; Qingyu Li; Zhixin Jiang; Xiaoyong Yuan
TAGS: allergic conjunctivitis, biological markers, mendelian randomization analysis, modified barium swallow, proteins
Trans. Vis. Sci. Tech.. 2025; 14(4):12. https://doi.org/10.1167/tvst.14.4.12

Includes: Supplemental Content

Review April 2025

An Emerging Global Threat of Mycotic Keratitis Caused by Uncommon Fungal Species: A Systematic Review and Meta-Analysis

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Megha Gautam; Babu Lal; Smita Patel; Rajiv R. Mohan; Arivarasan Barathi; Nikita Yadav; Sunil Kumar Verma; Richa Nyodu; Ananyan Sampath; Darshna Koshti; Bhavana Sharma
TAGS: fungal keratitis, meta-analysis, prevalence, systematic reviews, atypical, keratitis, treatment outcome, risk factors
Trans. Vis. Sci. Tech.. 2025; 14(4):4. https://doi.org/10.1167/tvst.14.4.4

Includes: Supplemental Content

Retina March 2025

Evaluation of Suprachoroidal Injection in Cadaveric and Preclinical Models

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Mark Hedgeland; Sergio Camacho Gonzalez; Dimitrios Stampoulis; Vivian Lee; Kate Powell; Yubin Qiu; Robert Hodge; Greg Bell; Amanda Fago; Rebecca Atkinson-Dell; Nadya Choti; Kirsten Stoner
TAGS: injections, eye, subcutaneous injections
Trans. Vis. Sci. Tech.. 2025; 14(3):20. https://doi.org/10.1167/tvst.14.3.20

Includes: Multimedia, Supplemental Content

Neuro-ophthalmology February 2025

New Method of Early RRMS Diagnosis Using OCT-Assessed Structural Retinal Data and Explainable Artificial Intelligence

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Miguel Ortiz; Ana Pueyo; Francisco J. Dongil; Luciano Boquete; Eva M. Sánchez-Morla; Rafael Barea; Juan M. Miguel-Jimenez; Almudena López-Dorado; Elisa Vilades; María J. Rodrigo; Beatriz Cordon; Elena Garcia-Martin
TAGS: artificial intelligence, multiple sclerosis, relapsing-remitting
Trans. Vis. Sci. Tech.. 2025; 14(2):14. https://doi.org/10.1167/tvst.14.2.14

Retina February 2025

Effect of the Sugar Present in the Culture Medium on the Preservation of Human RPE Cell Suspensions

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Shohei Kitahata; Hinako Ichikawa; Yuji Tanaka; Shin Tanaka; Tatsuya Inoue; Maiko Maruyama-Inoue; Kazuaki Kadonosono
TAGS: culture media, retinal pigment cell, sugars, fructose
Trans. Vis. Sci. Tech.. 2025; 14(2):1. https://doi.org/10.1167/tvst.14.2.1

Includes: Supplemental Content

Lacrimal Apparatus, Eyelids, Orbit January 2025

A Novel Rabbit Model of Meibomian Gland Dysfunction–Induced Dry Eye

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Annabelle Gallois-Bernos; Lichun Zhong; Mingqi Bai; Caroline A. Blackie
TAGS: cautery, developmental stages, dry eye syndromes, meibomian gland dysfunction, oryctolagus cuniculus, eye, tear film finding, meibomian gland
Trans. Vis. Sci. Tech.. 2025; 14(1):28. https://doi.org/10.1167/tvst.14.1.28

Editorial December 2024

Reviewers

PDF

TAGS: bsnd gene, gangs, happiness, laparoscopic uterosacral nerve ablation, reading (activity), tolnaftate, acetylcholine, achondroplasia, camurati-engelmann syndrome, e-selectin
Trans. Vis. Sci. Tech.. 2024; 13(12):38. https://doi.org/10.1167/tvst.13.12.38

Methods December 2024

Using Hierarchical Bayesian Modeling to Enhance Statistical Inference on Contrast Sensitivity

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Yukai Zhao; Luis Andres Lesmes; Michael Dorr; Zhong-Lin Lu
TAGS: carotid sinus syncope, churg-strauss syndrome, contrast sensitivity, inference, luminance, datasets
Trans. Vis. Sci. Tech.. 2024; 13(12):17. https://doi.org/10.1167/tvst.13.12.17

Includes: Supplemental Content

Cornea & External Disease December 2024

Corneal Confocal Microscopy Identifies and Differentiates Patients With Multiple Sclerosis and Epilepsy

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Ioannis N. Petropoulos; Kareem Essam Aly; Shaikha Al-Thani; Georgios Ponirakis; Hoda Gad; Adnan Khan; Beatriz Canibano; Dirk Deleu; Naveed Akhtar; Gayane Melikyan; Boulenouar Mesraoua; Maria Siddiqi; Jon Perkins; Novsheen Mir; Reny Francis; Abdul Salam; Ahmed El-Sotouhy; Surjith Vattoth; Ahmed Own; Saadat Kamran; Rayaz A. Malik
TAGS: cornea, epilepsy, microscopy, confocal, multiple sclerosis, nerve degeneration
Trans. Vis. Sci. Tech.. 2024; 13(12):22. https://doi.org/10.1167/tvst.13.12.22

Cornea & External Disease December 2024

The Effect of Terpinen-4-ol on Human Corneal Epithelium

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Joo-Hee Park; Choul Yong Park
TAGS: cell survival, cornea, corneal epithelium, epithelium, toxic effect, corneal epithelial cells, mass or substance concentration per volume, cell count, eyelid scrub, immunocytochemistry
Trans. Vis. Sci. Tech.. 2024; 13(12):18. https://doi.org/10.1167/tvst.13.12.18

Includes: Supplemental Content

Letters to the Editor December 2024

Is This Inflammation, Conjunctiva-Associated Lymphoid Tissue, or Tertiary Lymphoid Structures in These Rabbits?

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JoAnn C. L. Schuh
TAGS: conjunctiva, inflammation, lymphoid tissue, oryctolagus cuniculus, tertiary lymphoid structures
Trans. Vis. Sci. Tech.. 2024; 13(12):3. https://doi.org/10.1167/tvst.13.12.3

Cornea & External Disease November 2024

Efficacy of Terpinen-4-ol Combined With Eyelid Deep Cleaning for the Treatment of Demodex Blepharitis: A Randomized, Open-Label Trial

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Hao-Yu Wang; Dan Shen; Meng-Ying Qi; Chen Qiao; Lan Ke; Mingwu Wang; Qing-Yan Zeng
TAGS: blepharitis, eyelid, mites, ocular surfaces, eyelid margin, follow-up
Trans. Vis. Sci. Tech.. 2024; 13(11):22. https://doi.org/10.1167/tvst.13.11.22

Cornea & External Disease November 2024

Exploring New Links Among Keratoconus, Hormonal Factors, and Medications: Insights From a Case–Control Study Utilizing the All of Us Database

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Carol Beatty; Amy Estes; Hongyan Xu; Yutao Liu
TAGS: estrogen, keratoconus, pharmaceutical preparations, risk factors, obesity, medical history, dry eye syndromes
Trans. Vis. Sci. Tech.. 2024; 13(11):18. https://doi.org/10.1167/tvst.13.11.18

Glaucoma November 2024

Differentiating Multiple Sclerosis and Glaucoma With Sectoral Pattern Analysis of Peripapillary Nerve Fiber Layer

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Po-Han Yeh; Ou Tan; Elizabeth Silbermann; Elizabeth White; Dongseok Choi; Aiyin Chen; Eliesa Ing; Dennis Bourdette; Jie Wang; Yali Jia; David Huang
TAGS: eye, glaucoma, multiple sclerosis, nerve fibers
Trans. Vis. Sci. Tech.. 2024; 13(11):11. https://doi.org/10.1167/tvst.13.11.11

Retina October 2024

Automated Posterior Scleral Topography Assessment for Enhanced Staphyloma Visualization and Quantification With Improved Maculopathy Correlation

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Ying Xiang Han; Xiao Xiao Guo; Ya Xing Wang; Jost B. Jonas; Xi Chen; Xiao Fei Wang
TAGS: sclera, staphyloma, macular disorders, eye, magnetic resonance imaging
Trans. Vis. Sci. Tech.. 2024; 13(10):41. https://doi.org/10.1167/tvst.13.10.41

Includes: Supplemental Content

Cornea & External Disease September 2024

Causal Association Between Atopic Dermatitis and Keratoconus: A Mendelian Randomization Study

PDF

Yuan Chang; Tianze Huang; Shan Yang; Ying Li; Di Chen
TAGS: atopic dermatitis, keratoconus, mendelian randomization analysis, genome-wide association study, datasets
Trans. Vis. Sci. Tech.. 2024; 13(9):13. https://doi.org/10.1167/tvst.13.9.13

Includes: Supplemental Content

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Development of Deep Learning Models to Screen Posterior Staphylomas in Highly Myopic Eyes Using UWF-OCT Images

Aquaporin-4 Peptide Injection in Mice Induces Retinal and Optic Nerve Alterations That Simulate Those of Neuromyelitis Optica Spectrum Disorder

A Tear-Based Approach for Rapid Identification of Bacterial Pathogens in Corneal Ulcers Using Nanopore Sequencing

Causal Relationship Between Common Allergic Diseases and Keratoconus: A Two-Sample Mendelian Randomization Study

Metabolic Biomarkers Mediate Allergic Conjunctivitis via Circulating Inflammatory Proteins: Evidence From a Mendelian Randomization Study

An Emerging Global Threat of Mycotic Keratitis Caused by Uncommon Fungal Species: A Systematic Review and Meta-Analysis

Evaluation of Suprachoroidal Injection in Cadaveric and Preclinical Models

New Method of Early RRMS Diagnosis Using OCT-Assessed Structural Retinal Data and Explainable Artificial Intelligence

Effect of the Sugar Present in the Culture Medium on the Preservation of Human RPE Cell Suspensions

A Novel Rabbit Model of Meibomian Gland Dysfunction–Induced Dry Eye

Reviewers

Using Hierarchical Bayesian Modeling to Enhance Statistical Inference on Contrast Sensitivity

Corneal Confocal Microscopy Identifies and Differentiates Patients With Multiple Sclerosis and Epilepsy

The Effect of Terpinen-4-ol on Human Corneal Epithelium

Is This Inflammation, Conjunctiva-Associated Lymphoid Tissue, or Tertiary Lymphoid Structures in These Rabbits?

Efficacy of Terpinen-4-ol Combined With Eyelid Deep Cleaning for the Treatment of Demodex Blepharitis: A Randomized, Open-Label Trial

Exploring New Links Among Keratoconus, Hormonal Factors, and Medications: Insights From a Case–Control Study Utilizing the All of Us Database

Differentiating Multiple Sclerosis and Glaucoma With Sectoral Pattern Analysis of Peripapillary Nerve Fiber Layer

Automated Posterior Scleral Topography Assessment for Enhanced Staphyloma Visualization and Quantification With Improved Maculopathy Correlation

Causal Association Between Atopic Dermatitis and Keratoconus: A Mendelian Randomization Study

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