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Lens May 2025

LncRNA HOTAIR Interaction With WTAP Promotes m 6 A Methyltransferase Complex Assembly and Posterior Capsule Opacification Formation by Increasing THBS1

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Xi Chen; Chenshuang Li; Jiankui Li; Zaoxia Guo; Siqi Zhang; Chenjun Guo; Hong Yan
TAGS: after-cataract, epithelial to mesenchymal transition, methyltransferase, proteins, rna, thrombospondin 1, western blotting, protein overexpression, polymerase chain reaction, cataract surgery
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):20. https://doi.org/10.1167/iovs.66.5.20

Includes: Supplemental Content

Lens May 2025

Cholesterol and Q147E Deamidation Modulates αA-Crystallin Membrane Binding Elucidating Protective Role of Lens Membrane Composition Changes With Aging

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Preston Hazen; Nawal K. Khadka; Laxman Mainali
TAGS: crystallins, lens (device), lens, crystalline, tissue membrane, cholesterol, aging, lipids
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):8. https://doi.org/10.1167/iovs.66.5.8

Clinical and Epidemiologic Research May 2025

Three-Year Change in Subfoveal Choroidal Thickness and Area With Multifocal Contact Lens Wear in the Bifocal Lenses in Nearsighted Kids (BLINK) Study

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Maria K. Walker; David A. Berntsen; Matt L. Robich; Rachel L. Fenton; Anita Ticak; Justina R. Assaad; Hope M. Queener; Stephanie J. Chiu; Sina Farsiu; Donald O. Mutti; Lisa A. Jones-Jordan; Jeffrey J. Walline; for the BLINK Study Group
TAGS: child, choroid, contact lenses, lens (device), lens, crystalline, myopia
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):5. https://doi.org/10.1167/iovs.66.5.5

Includes: Supplemental Content

Lens May 2025

RNA-Seq Study of Human Lens Epithelial Cells: Differentially Expressed Genes and Pathways in Steroid, Uveitic, Post-Vitrectomy, and Senile Cataracts

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Carrie Fei; Michael R. Dong; Sean Byars; Jaynish S. Shah; Anthony J. Hall; Lyndell L. Lim
TAGS: after-cataract, cataract, cataract, senile, epithelial cells, genes, lens, crystalline, rna-seq, steroids, vitrectomy, rna
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):4. https://doi.org/10.1167/iovs.66.5.4

Includes: Supplemental Content

Artificial Intelligence May 2025

PhacoTrainer: Automatic Artificial Intelligence-Generated Performance Ratings for Cataract Surgery

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Hsu-Hang Yeh; Simmi Sen; Jonathan C. Chou; Karen L. Christopher; Sophia Y. Wang
TAGS: cataract, cataract surgery, intelligence, surgeons, surgical procedures, operative, phacoemulsification, eye
Trans. Vis. Sci. Tech.. 2025; 14(5):2. https://doi.org/10.1167/tvst.14.5.2

Includes: Supplemental Content

Lens April 2025

Macrophage-Hosted Porphyromonas gingivalis Is a Risk Factor for Cataract Development

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Dongzhe Zhang; Junwei Qu; Cuncun Ke; Xiumei Kong; Mengyun Liu; Iqbal Nawaz Khan; Shuxin Huang; Haijiao Tian; Tong Xie; Ke Qiu; Jing Li; Mingli Wang; Hui Li; Fengling Yuan; Weikai Guo; Mingya Cao; Jing Zhang; Keke Zhu; Jin Luo; Fengyan Zhang; Xiukun Cui; Hongmei Mu; Yanzhong Hu
TAGS: body tissue, cataract, epithelium, infections, lens (device), macrophages, risk factors, porphyromonas gingivalis, hypertension, lens, crystalline
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):68. https://doi.org/10.1167/iovs.66.4.68

Includes: Supplemental Content

Lens April 2025

Transcriptome Meta-Analysis Uncovers Cell-Specific Regulatory Relationships in Embryonic, Juvenile, Adult, and Aged Mouse Lens Epithelium and Fibers

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Matthieu Duot; Sarah Y. Coomson; Sanjaya K. Shrestha; M. V. Murali Krishna Nagulla; Yann Audic; Ruteja A. Barve; Hongzhan Huang; Carole Gautier-Courteille; Luc Paillard; Salil A. Lachke
TAGS: datasets, embryo, epithelium, genes, lens epithelium, meta-analysis, mice, lens (device), lens, crystalline, adult
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):42. https://doi.org/10.1167/iovs.66.4.42

Includes: Supplemental Content

Lens April 2025

Elevated Inflammatory Cytokines Persist in the Aqueous Humor Years After Cataract Surgery

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Caili Hao; Emily Fan; Zongbo Wei; Kazi Rafsan Radeen; Neha Purohit; Kailin Li; Sharad Purohit; Xingjun Fan
TAGS: cataract, cataract surgery, chronic inflammation, cytokine, hypertension, surgical procedures, operative, aqueous humor, surgery specialty, donors
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):12. https://doi.org/10.1167/iovs.66.4.12

Includes: Supplemental Content

Lens April 2025

In Vivo Brillouin Analysis of Lens Nucleus and Cortex in Adult Myopic Eyes and Their Correlation With Accommodation

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Le Chang; Fen Song; Shijia Qu; Huazheng Cao; Yanan Wu; Lulu Xu; Jing Wang; Ruirui Zhang; Chao Xue; Yan Wang
TAGS: cell nucleus, eye, lens (device), lens, crystalline, myopia, visual accommodation, adult, regression analysis
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):6. https://doi.org/10.1167/iovs.66.4.6

Includes: Supplemental Content

Refractive Intervention April 2025

Assessment of Corneal Biomechanical Changes After Discontinuation of Long-Term Orthokeratology: A 2-Year Prospective Study

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Hou-Ren Tsai; Jeng-Hung Wang; Cheng-Jen Chiu
TAGS: cornea, orthokeratology, prospective studies, lens (device), lens, crystalline
Trans. Vis. Sci. Tech.. 2025; 14(4):5. https://doi.org/10.1167/tvst.14.4.5

Includes: Supplemental Content

Lens April 2025

Association of Per- and Polyfluoroalkyl Substance Exposure With Cataract Prevalence Among U.S. Adults: A NHANES Analysis (2005–2008)

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Yuti Liu; Jiazhen Yao; Mingxue Ren; Lingxia Ye; An-Peng Pan; Xu Xu
TAGS: cataract, fluorocarbons, prevalence, national health and nutrition examination survey, adult
Trans. Vis. Sci. Tech.. 2025; 14(4):1. https://doi.org/10.1167/tvst.14.4.1

Includes: Supplemental Content

Optica Fall Vision Meeting Abstract April 2025

Contributed Talks III: The Berkeley Widefield Model Eye

Austin Roorda; Pavan Tiruveedhula; Gareth Dudley Hastings
TAGS: eye
Journal of Vision. 2025; 25(5):56. https://doi.org/10.1167/jov.25.5.56

Optica Fall Vision Meeting Abstract April 2025

Poster Session: Geometric phase multifocal ophthalmic lenses for presbyopics

Sunil Kumar Chaubey; Brian Vohnsen
TAGS: eye, lens (device), lens, crystalline, posters
Journal of Vision. 2025; 25(5):50. https://doi.org/10.1167/jov.25.5.50

Optica Fall Vision Meeting Abstract April 2025

Poster Session: Measuring the limits of long-term adaptation to hue-rotated altered reality

Yesesvi Somayaji Konakanchi; Jenny Bosten; Anna Franklin; John Maule
TAGS: posters
Journal of Vision. 2025; 25(5):40. https://doi.org/10.1167/jov.25.5.40

Optica Fall Vision Meeting Abstract April 2025

Contributed talks II: Sensitivity to temporally modulated defocus for different monochromatic stimuli

Victor Rodriguez-Lopez; Carlos Dorronsoro
TAGS: color, flicker fusion, lens (device), lens, crystalline, optics, perception, stairs, technology
Journal of Vision. 2025; 25(5):36. https://doi.org/10.1167/jov.25.5.36

Anatomy and Pathology/Oncology March 2025

Lens Thickness-to-Anterior Chamber Depth Ratio: A Biometric Determinant of Chamber Angle Width in Han Chinese Cataract Patients

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Ao Miao; Fan Yang; Tianhui Chen; Dongjin Qian; Yongxiang Jiang; Jie Xu; Tianyu Zheng
TAGS: anterior chamber of eye, biometry, cataract, chinese (other dialects), chinese people, lens (device), lens, crystalline, eye
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):42. https://doi.org/10.1167/iovs.66.3.42

Visual Psychophysics and Physiological Optics March 2025

Age-Related Changes in Mesopic Reading Vision Across Adulthood

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Boris Peñaloza; Traci-Lin Goddin; David S. Friedman; Cynthia Owsley; MiYoung Kwon
TAGS: reading (activity), vision, adult
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):40. https://doi.org/10.1167/iovs.66.3.40

Lens March 2025

Changes in Lens Thickness and Power Before and After Myopia Onset

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Jiaqing Zhang; Ling Jin; Qianyun Chen; Decai Wang; Xiang Chen; Yuting Li; Yabin Qu; Rong Lin; Mingguang He; Ian G. Morgan; Lixia Luo; Yangfa Zeng; Xiaotong Han
TAGS: lens, crystalline, myopia, child
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):36. https://doi.org/10.1167/iovs.66.3.36

Includes: Supplemental Content

Cornea March 2025

A Novel Model for Cornea Power Shift in Eyes Wearing Orthokeratology Lenses With Different Back Optic Zone Diameters for Myopia Control

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Ting Wang; Xiaoqin Chen; Mengdi Li; Hua Bi; Xiaoyan Yang; Muhan Sun; Yue Liu; Lihua Li; Bin Zhang
TAGS: cornea, eye, lens (device), lens, crystalline, myopia, orthokeratology contact lenses, optics
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):29. https://doi.org/10.1167/iovs.66.3.29

Includes: Supplemental Content

Pediatric Ophthalmology & Strabismus March 2025

The Peripheral Defocus Designed Spectacle Lenses Might Increase Astigmatism in Myopic Children

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Wenyan Xu; Xiaoman Li; Jianing Zhang; Hongyi Li; Xuewen Ding; Xiaoyue Hu; Xinyue Quan; Yue Su; Fan Lu; Jie Chen
TAGS: astigmatism, child, lens (device), lens, crystalline, myopia, refractive errors
Trans. Vis. Sci. Tech.. 2025; 14(3):8. https://doi.org/10.1167/tvst.14.3.8

Includes: Supplemental Content

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LncRNA HOTAIR Interaction With WTAP Promotes m 6 A Methyltransferase Complex Assembly and Posterior Capsule Opacification Formation by Increasing THBS1

Cholesterol and Q147E Deamidation Modulates αA-Crystallin Membrane Binding Elucidating Protective Role of Lens Membrane Composition Changes With Aging

Three-Year Change in Subfoveal Choroidal Thickness and Area With Multifocal Contact Lens Wear in the Bifocal Lenses in Nearsighted Kids (BLINK) Study

RNA-Seq Study of Human Lens Epithelial Cells: Differentially Expressed Genes and Pathways in Steroid, Uveitic, Post-Vitrectomy, and Senile Cataracts

PhacoTrainer: Automatic Artificial Intelligence-Generated Performance Ratings for Cataract Surgery

Macrophage-Hosted Porphyromonas gingivalis Is a Risk Factor for Cataract Development

Transcriptome Meta-Analysis Uncovers Cell-Specific Regulatory Relationships in Embryonic, Juvenile, Adult, and Aged Mouse Lens Epithelium and Fibers

Elevated Inflammatory Cytokines Persist in the Aqueous Humor Years After Cataract Surgery

In Vivo Brillouin Analysis of Lens Nucleus and Cortex in Adult Myopic Eyes and Their Correlation With Accommodation

Assessment of Corneal Biomechanical Changes After Discontinuation of Long-Term Orthokeratology: A 2-Year Prospective Study

Association of Per- and Polyfluoroalkyl Substance Exposure With Cataract Prevalence Among U.S. Adults: A NHANES Analysis (2005–2008)

Contributed Talks III: The Berkeley Widefield Model Eye

Poster Session: Geometric phase multifocal ophthalmic lenses for presbyopics

Poster Session: Measuring the limits of long-term adaptation to hue-rotated altered reality

Contributed talks II: Sensitivity to temporally modulated defocus for different monochromatic stimuli

Lens Thickness-to-Anterior Chamber Depth Ratio: A Biometric Determinant of Chamber Angle Width in Han Chinese Cataract Patients

Age-Related Changes in Mesopic Reading Vision Across Adulthood

Changes in Lens Thickness and Power Before and After Myopia Onset

A Novel Model for Cornea Power Shift in Eyes Wearing Orthokeratology Lenses With Different Back Optic Zone Diameters for Myopia Control

The Peripheral Defocus Designed Spectacle Lenses Might Increase Astigmatism in Myopic Children

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