Nanotechnology and Regenerative Medicine

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Articles April 2018

Inhibitory Effects of Angiotensin II Receptor Blockade on Human Tenon Fibroblast Migration and Reactive Oxygen Species Production in Cell Culture

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Duri Kim; Ushasree Pattamatta; Elizabeth Kelly; Paul R. Healey; Nicole Carnt; Hans Zoellner; Andrew J. R. White
TAGS: angiotensins, irbesartan, cell culture techniques, receptor, angiotensin ii, angiotensin ii, fibroblasts, cell count, reactive oxygen species
Trans. Vis. Sci. Tech.. 2018; 7(2):20. doi: 10.1167/tvst.7.2.20

Articles July 2017

Impact of Vital Dyes on Cell Viability and Transduction Efficiency of AAV Vectors Used in Retinal Gene Therapy Surgery: An In Vitro and In Vivo Analysis

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Anna P. Salvetti; Maria I. Patrício; Alun R. Barnard; Harry O. Orlans; Doron G. Hickey; Robert E. MacLaren
TAGS: gene therapy, cell survival, dyes, injection of therapeutic agent, surgical procedures, operative, toxic effect, spatial vectors
Trans. Vis. Sci. Tech.. 2017; 6(4):4. doi: 10.1167/tvst.6.4.4

Includes: Supplemental Content

Articles June 2017

Da Vinci Xi Robot–Assisted Penetrating Keratoplasty

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Jimmy Chammas; Arnaud Sauer; Joëlle Pizzuto; Fabienne Pouthier; David Gaucher; Jacques Marescaux; Didier Mutter; Tristan Bourcier
TAGS: keratoplasty, penetrating, ophthalmologic surgical procedures, surgical procedures, operative, sutures, cornea, spectral-domain optical coherence tomography
Trans. Vis. Sci. Tech.. 2017; 6(3):21. doi: 10.1167/tvst.6.3.21

Articles June 2017

Long-Term Efficacy of GMP Grade Xeno-Free hESC-Derived RPE Cells Following Transplantation

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Trevor J. McGill; Osnat Bohana-Kashtan; Jonathan W. Stoddard; Michael D. Andrews; Neelay Pandit; Lior R. Rosenberg-Belmaker; Ofer Wiser; Limor Matzrafi; Eyal Banin; Benjamin Reubinoff; Nir Netzer; Charles Irving
TAGS: photoreceptors, eye, retina, transplantation, good manufacturing practice, retinal pigment cell
Trans. Vis. Sci. Tech.. 2017; 6(3):17. doi: 10.1167/tvst.6.3.17

Articles May 2017

Transplantation of Human Embryonic Stem Cell-Derived Retinal Cells into the Subretinal Space of a Non-Human Primate

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Jennifer R. Chao; Deepak A. Lamba; Todd R. Klesert; Anna La Torre; Akina Hoshino; Russell J. Taylor; Anu Jayabalu; Abbi L. Engel; Thomas H. Khuu; Ruikang K. Wang; Maureen Neitz; Jay Neitz; Thomas A. Reh
TAGS: embryo, primates, diagnostic imaging, eye, optic nerve, retina, transplantation
Trans. Vis. Sci. Tech.. 2017; 6(3):4. doi: 10.1167/tvst.6.3.4

Articles January 2017

Retinoic Acid Enhances the Differentiation of Adipose-Derived Stem Cells to Keratocytes In Vitro

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Amy P. Lynch; Mark Ahearne
TAGS: western blotting, cell proliferation, stem cells, tretinoin, keratocytes
Trans. Vis. Sci. Tech.. 2017; 6(1):6. doi: 10.1167/tvst.6.1.6

Includes: Supplemental Content

Articles November 2016

ROCK Inhibition Promotes Attachment, Proliferation, and Wound Closure in Human Embryonic Stem Cell–Derived Retinal Pigmented Epithelium

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Roxanne H. Croze; William J. Thi; Dennis O. Clegg
TAGS: embryonic stem cells, epithelium, wounds and injuries, wound closure
Trans. Vis. Sci. Tech.. 2016; 5(6):7. doi: 10.1167/tvst.5.6.7

Includes: Supplemental Content

Articles October 2016

Test–Retest Variability of Functional and Structural Parameters in Patients with Stargardt Disease Participating in the SAR422459 Gene Therapy Trial

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Maria A. Parker; Dongseok Choi; Laura R. Erker; Mark E. Pennesi; Paul Yang; Elvira N. Chegarnov; Peter N. Steinkamp; Catherine L. Schlechter; Claire-Marie Dhaenens; Saddek Mohand-Said; Isabelle Audo; Jose Sahel; Richard G. Weleber; David J. Wilson
TAGS: gene therapy, perimetry, visual acuity, visual fields, eye, stargardt's disease, spectral-domain optical coherence tomography
Trans. Vis. Sci. Tech.. 2016; 5(5):10. doi: 10.1167/tvst.5.5.10

Includes: Supplemental Content

Articles July 2016

Efficacy and Safety of Human Retinal Progenitor Cells

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Ma'ayan Semo; Nasrin Haamedi; Lara Stevanato; David Carter; Gary Brooke; Michael Young; Peter Coffey; John Sinden; Sara Patel; Anthony Vugler
TAGS: dexamethasone, stem cells, injection of therapeutic agent, safety, vision, eye, rats, transplantation, prostate cancer, hormone-refractory
Trans. Vis. Sci. Tech.. 2016; 5(4):6. doi: 10.1167/tvst.5.4.6

Includes: Supplemental Content

Articles September 2015

The Effect of Transient Local Anti-inflammatory Treatment on the Survival of Pig Retinal Progenitor Cell Allotransplants

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Murilo Abud; Petr Baranov; Caroline Hicks; Sara Patel; Burke Lieppman; Caio Regatieri; John Sinden; David Isaac; Marcos Avila; Michael Young
TAGS: anti-inflammatory agents, stem cells, photoreceptors, prpc proteins, reverse transcriptase polymerase chain reaction, rhodopsin, transplantation, homologous, therapeutic immunosuppression, transplantation, immunocytochemistry
Trans. Vis. Sci. Tech.. 2015; 4(5):6. doi: 10.1167/tvst.4.5.6

Includes: Supplemental Content

Articles February 2015

A Subsequent Human Neural Progenitor Transplant into the Degenerate Retina Does Not Compromise Initial Graft Survival or Therapeutic Efficacy

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B.n. Lu; Yanhua Lin; Yuchun Tsai; Sergey Girman; Grazyna Adamus; Melissa K. Jones; Brandon Shelley; Clive N. Svendsen; Shaomei Wang
TAGS: graft survival, photoreceptors, tissue transplants, vision, eye, rats, retina, transplantation, did not receive therapy or drug
Trans. Vis. Sci. Tech.. 2015; 4(1):7. doi: 10.1167/tvst.4.1.7

Includes: Supplemental Content

Articles January 2015

Automated Detection and Quantification of Circadian Eye Blinks Using a Contact Lens Sensor

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Christophe Gisler; Antonio Ridi; Jean Hennebert; Robert N. Weinreb; Kaweh Mansouri
TAGS: contact lenses, eye, intraocular pressure, sleep, sensor
Trans. Vis. Sci. Tech.. 2015; 4(1):4. doi: 10.1167/tvst.4.1.4

Includes: Multimedia, Supplemental Content

Articles December 2014

Chapter 3 - Restoring Vision to the Blind: Gene Therapy for Vision Loss

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The Lasker/IRRF Initiative for Innovation in Vision Science
TAGS: gene therapy, blindness, vision
Trans. Vis. Sci. Tech.. 2014; 3(7):5. doi: 10.1167/tvst.3.7.5

Includes: Supplemental Content

Articles December 2014

Chapter 4 - Restoring Vision to the Blind: Stem Cells and Transplantation

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The Lasker/IRRF Initiative for Innovation in Vision Science
TAGS: stem cells, photoreceptors, vision, transplantation
Trans. Vis. Sci. Tech.. 2014; 3(7):6. doi: 10.1167/tvst.3.7.6

Includes: Supplemental Content

Articles December 2014

Chapter 5 - Restoring Vision to the Blind: Endogenous Regeneration

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The Lasker/IRRF Initiative for Innovation in Vision Science
TAGS: amphibia, mammals, vision, retina
Trans. Vis. Sci. Tech.. 2014; 3(7):7. doi: 10.1167/tvst.3.7.7

Includes: Supplemental Content

Articles December 2014

Restoring Vision to the Blind: The Lasker/IRRF Initiative for Innovation in Vision Science

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The Lasker/IRRF Initiative for Innovation in Vision Science
TAGS: vision
Trans. Vis. Sci. Tech.. 2014; 3(7):1. doi: 10.1167/tvst.3.7.1

Includes: Supplemental Content

Articles December 2014

Restoring Vision to the Blind: Concluding Remarks

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John E. Dowling
TAGS: vision
Trans. Vis. Sci. Tech.. 2014; 3(7):11. doi: 10.1167/tvst.3.7.11

Includes: Supplemental Content

Articles December 2014

Restoring Vision to the Blind: Introduction

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John E. Dowling
TAGS: vision
Trans. Vis. Sci. Tech.. 2014; 3(7):2. doi: 10.1167/tvst.3.7.2

Includes: Supplemental Content

Perspective October 2014

Novel Approaches for Retinal Drug and Gene Delivery

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Stephen J. Kim
TAGS: gene therapy, anti-inflammatory agents, non-steroidal, drug delivery systems, genes, hydrogels, animal model, retinal diseases, intravitreal injections
Trans. Vis. Sci. Tech.. 2014; 3(5):7. doi: 10.1167/tvst.3.5.7

Articles July 2014

Methods of Retinal Ganglion Cell Differentiation From Pluripotent Stem Cells

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Katherine P. Gill; Alex W. Hewitt; Kathryn C. Davidson; Alice Pébay; Raymond C. B. Wong
TAGS: stem cells, culture media, retinal ganglion cells, eye, mice, stem cells, pluripotent
Trans. Vis. Sci. Tech.. 2014; 3(4):2. doi: 10.1167/tvst.3.4.2

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Inhibitory Effects of Angiotensin II Receptor Blockade on Human Tenon Fibroblast Migration and Reactive Oxygen Species Production in Cell Culture

Impact of Vital Dyes on Cell Viability and Transduction Efficiency of AAV Vectors Used in Retinal Gene Therapy Surgery: An In Vitro and In Vivo Analysis

Da Vinci Xi Robot–Assisted Penetrating Keratoplasty

Long-Term Efficacy of GMP Grade Xeno-Free hESC-Derived RPE Cells Following Transplantation

Transplantation of Human Embryonic Stem Cell-Derived Retinal Cells into the Subretinal Space of a Non-Human Primate

Retinoic Acid Enhances the Differentiation of Adipose-Derived Stem Cells to Keratocytes In Vitro

ROCK Inhibition Promotes Attachment, Proliferation, and Wound Closure in Human Embryonic Stem Cell–Derived Retinal Pigmented Epithelium

Test–Retest Variability of Functional and Structural Parameters in Patients with Stargardt Disease Participating in the SAR422459 Gene Therapy Trial

Efficacy and Safety of Human Retinal Progenitor Cells

The Effect of Transient Local Anti-inflammatory Treatment on the Survival of Pig Retinal Progenitor Cell Allotransplants

A Subsequent Human Neural Progenitor Transplant into the Degenerate Retina Does Not Compromise Initial Graft Survival or Therapeutic Efficacy

Automated Detection and Quantification of Circadian Eye Blinks Using a Contact Lens Sensor

Chapter 3 - Restoring Vision to the Blind: Gene Therapy for Vision Loss

Chapter 4 - Restoring Vision to the Blind: Stem Cells and Transplantation

Chapter 5 - Restoring Vision to the Blind: Endogenous Regeneration

Restoring Vision to the Blind: The Lasker/IRRF Initiative for Innovation in Vision Science

Restoring Vision to the Blind: Concluding Remarks

Restoring Vision to the Blind: Introduction

Novel Approaches for Retinal Drug and Gene Delivery

Methods of Retinal Ganglion Cell Differentiation From Pluripotent Stem Cells

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