Oncology

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Articles February 2021

White Paper on Ophthalmic Imaging for Choroidal Nevus Identification and Transformation into Melanoma

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Carol L. Shields; Sara E. Lally; Lauren A. Dalvin; Mandeep S. Sagoo; Marco Pellegrini; Swathi Kaliki; Ahmet Kaan Gündüz; Minoru Furuta; Prithvi Mruthyunjaya; Adrian T. Fung; Jay S. Duker; Sara M. Selig; Antonio Yaghy; Sandor R. Ferenczy; Malvina B. Eydelman; Mark S. Blumenkranz
TAGS: melanoma, nevus, nevus of choroid, ophthalmic imaging
Trans. Vis. Sci. Tech.. 2021; 10(2):24. doi: https://doi.org/10.1167/tvst.10.2.24

Articles September 2020

Cell-Free DNA Tumor Fraction in the Aqueous Humor Is Associated With Therapeutic Response in Retinoblastoma Patients

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Ashley Polski; Liya Xu; Rishvanth K. Prabakar; Jonathan W. Kim; Rachana Shah; Rima Jubran; Peter Kuhn; David Cobrinik; James Hicks; Jesse L. Berry
TAGS: aqueous humor, cell-free dna, neoplasms, retinoblastoma, hypertension
Trans. Vis. Sci. Tech.. 2020; 9(10):30. doi: https://doi.org/10.1167/tvst.9.10.30

Includes: Supplemental Content

Special Issue September 2020

Piloting a Deep Learning Model for Predicting Nuclear BAP1 Immunohistochemical Expression of Uveal Melanoma from Hematoxylin-and-Eosin Sections

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Hongrun Zhang; Helen Kalirai; Amelia Acha-Sagredo; Xiaoyun Yang; Yalin Zheng; Sarah E. Coupland
TAGS: bap1 gene, deep learning, eosine yellowish-(ys), hematoxylin, intraocular melanoma, neoplasms, training
Trans. Vis. Sci. Tech.. 2020; 9(2):50. doi: https://doi.org/10.1167/tvst.9.2.50

Includes: Supplemental Content

Editorial July 2020

The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

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Marco Zarbin
TAGS: peer review, science
Trans. Vis. Sci. Tech.. 2020; 9(8):r. doi: https://doi.org/10.1167/tvst.9.8.r

Articles July 2020

Comparison of Current Optical Coherence Tomography Angiography Methods in Imaging Retinal Hemangioblastomas

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Michael Reich; Andreas Glatz; Daniel Boehringer; Charlotte Evers; Moritz Daniel; Felicitas Bucher; Franziska Ludwig; Simone Nuessle; Wolf A. Lagrèze; Peter M. Maloca; Clemens Lange; Thomas Reinhard; Hansjuergen Agostini; Stefan J. Lang
TAGS: angiogram, diagnostic imaging, optical coherence tomography, retinal hemangioblastoma, tumor size, neoplasms
Trans. Vis. Sci. Tech.. 2020; 9(8):12. doi: https://doi.org/10.1167/tvst.9.8.12

Includes: Supplemental Content

Articles July 2020

Benzalkonium Chloride Resistance in Staphylococcus epidermidis on the Ocular Surface of Glaucoma Patients Under Long-Term Administration of Eye Drops

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Jinhee Lee; Takuya Iwasaki; Shinichiro Ohtani; Hidehito Matsui; Ryohei Nejima; Yosai Mori; Fumie Kagaya; Akiko Yagi; Akiko Yoshimura; Hideaki Hanaki; Makoto Aihara; Kazunori Miyata
TAGS: bacterial artificial chromosomes, benzalkonium chloride, blood alcohol concentration, bronchioloalveolar carcinoma, eyedrops, genes, glaucoma, staphylococcus epidermidis, polymerase chain reaction
Trans. Vis. Sci. Tech.. 2020; 9(8):9. doi: https://doi.org/10.1167/tvst.9.8.9

Includes: Supplemental Content

Articles June 2020

Cherenkov Luminescence Imaging for Assessment of Radioactive Plaque Position in Brachytherapy of Uveal Melanoma: An In Vivo Feasibility Study

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Jørgen Krohn; Yi-Chun Chen; Nils Ole Stabo-Eeg; Børge Hamre
TAGS: brachytherapy, diagnostic imaging, feasibility studies, intraocular melanoma, luminescence, neoplasms, radioactivity, ruthenium
Trans. Vis. Sci. Tech.. 2020; 9(7):42. doi: https://doi.org/10.1167/tvst.9.7.42

Articles June 2020

Characterization of Uveal Melanoma Cell Lines and Primary Tumor Samples in 3D Culture

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Karen Aughton; Haleh Shahidipour; Luna Djirackor; Sarah E. Coupland; Helen Kalirai
TAGS: cell lines, intraocular melanoma, neoplasms, spheroids, cellular
Trans. Vis. Sci. Tech.. 2020; 9(7):39. doi: https://doi.org/10.1167/tvst.9.7.39

Includes: Supplemental Content

Methods March 2020

An Automated Method for Assessing Topographical Structure–Function Agreement in Abnormal Glaucomatous Regions

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Emmanouil Tsamis; Nikhil K. Bommakanti; Ashley Sun; Kaveri A. Thakoor; Carlos Gustavo De Moraes; Donald C. Hood
TAGS: adams-stokes syndrome, afghanistan, american samoa, angelman syndrome, ankylosing spondylitis, aortic valve stenosis, arsenic, arteriosclerosis, atherosclerosis, atrial fibrillation
Trans. Vis. Sci. Tech.. 2020; 9(4):14. doi: https://doi.org/10.1167/tvst.9.4.14

Includes: Supplemental Content

Special Issue February 2020

A Clinician's Guide to Artificial Intelligence: How to Critically Appraise Machine Learning Studies

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Livia Faes; Xiaoxuan Liu; Siegfried K. Wagner; Dun Jack Fu; Konstantinos Balaskas; Dawn A. Sim; Lucas M. Bachmann; Pearse A. Keane; Alastair K. Denniston
TAGS: artificial intelligence, datasets, machine learning
Trans. Vis. Sci. Tech.. 2020; 9(2):7. doi: https://doi.org/10.1167/tvst.9.2.7

Articles February 2020

VEGFR1-Targeted Contrast-Enhanced Ultrasound Imaging Quantification of Vasculogenic Mimicry Microcirculation in a Mouse Model of Choroidal Melanoma

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Haiyun Liu; Min Gao; Jiying Gu; Xiaoling Wan; Hong Wang; Qing Gu; Yifan Zhou; Xiaodong Sun
TAGS: diagnostic imaging, malignant melanoma of choroid, melanoma, neoplasms, mice, ultrasonography, contrast-enhanced, microcirculation, modified barium swallow, eye melanomas
Trans. Vis. Sci. Tech.. 2020; 9(3):4. doi: https://doi.org/10.1167/tvst.9.3.4

Articles November 2019

A Panel of Circulating MicroRNAs Detects Uveal Melanoma With High Precision

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Mitchell S. Stark; Elin S. Gray; Timothy Isaacs; Fred K. Chen; Michael Millward; Ashleigh McEvoy; Pauline Zaenker; Melanie Ziman; H. Peter Soyer; William J. Glasson; Sunil K. Warrier; Andrew L. Stark; Olivia J. Rolfe; Jane M. Palmer; Nicholas K. Hayward
TAGS: intraocular melanoma, micrornas, precision
Trans. Vis. Sci. Tech.. 2019; 8(6):12. doi: https://doi.org/10.1167/tvst.8.6.12

Includes: Supplemental Content

Articles September 2019

In Vitro Evaluation of the Inhibitory Effect of Topical Ophthalmic Agents on Acanthamoeba Viability

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Wayne Heaselgrave; Anas Hamad; Steven Coles; Scott Hau
TAGS: acanthamoeba, cysts, ophthalmic agents, trophozoite, bronchioloalveolar carcinoma, toxic effect
Trans. Vis. Sci. Tech.. 2019; 8(5):17. doi: https://doi.org/10.1167/tvst.8.5.17

Articles September 2019

Magnetic Hyperthermia in Y79 Retinoblastoma and ARPE-19 Retinal Epithelial Cells: Tumor Selective Apoptotic Activity of Iron Oxide Nanoparticle

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Hakan Demirci; Naziha Slimani; Mercy Pawar; Ronald E. Kumon; Prem Vaishnava; Cagri G. Besirli
TAGS: ferumoxytol, hyperthermia, nanoparticles, neoplasms, retinoblastoma, epithelial cells
Trans. Vis. Sci. Tech.. 2019; 8(5):18. doi: https://doi.org/10.1167/tvst.8.5.18

Includes: Supplemental Content

Editorial August 2019

The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

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Marco Zarbin
TAGS: peer review, science
Trans. Vis. Sci. Tech.. 2019; 8(4):r. doi: https://doi.org/10.1167/tvst.8.4.r

Articles June 2019

In Vitro Effect of Toluidine Blue Antimicrobial Photodynamic Chemotherapy on Staphylococcus epidermidis and Staphylococcus aureus Isolated from Ocular Surface Infection

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Jing Shen; Qingfeng Liang; Guanyu Su; Yang Zhang; Zhiqun Wang; Christophe Baudouin; Antoine Labbé
TAGS: antimicrobials, chemotherapy regimen, infections, mass or substance concentration per volume, staphylococcus aureus, staphylococcus epidermidis, tolonium chloride, bacteria, anti-bacterial agents, photosensitizing agents
Trans. Vis. Sci. Tech.. 2019; 8(3):45. doi: https://doi.org/10.1167/tvst.8.3.45

Articles May 2019

Smartphone-Based, Rapid, Wide-Field Fundus Photography for Diagnosis of Pediatric Retinal Diseases

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Tapan P. Patel; Tyson N. Kim; Gina Yu; Vaidehi S. Dedania; Philip Lieu; Cynthia X. Qian; Cagri G. Besirli; Hakan Demirci; Todd Margolis; Daniel A. Fletcher; Yannis M. Paulus
TAGS: cell phones, diagnostic imaging, diagnostic imaging of retina, fundus photography, pediatrics, retinal diseases, child, retina
Trans. Vis. Sci. Tech.. 2019; 8(3):29. doi: https://doi.org/10.1167/tvst.8.3.29

Articles May 2019

Detection of Malignancy in Ocular Surface Lesions by Inverse Spectroscopic Optical Coherence Tomography and Two-Photon Autofluorescence

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Hyunjoo Jean Lee; Lei Zhang; Sui Zhang; Ji Yi
TAGS: autofluorescence, cancer, optical coherence tomography, photons, precancerous conditions, diagnostic imaging, body tissue
Trans. Vis. Sci. Tech.. 2019; 8(3):16. doi: https://doi.org/10.1167/tvst.8.3.16

Articles May 2019

Digital Image Analysis of BAP-1 Accurately Predicts Uveal Melanoma Metastasis

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Gustav Stålhammar; Thonnie Rose O. See; Stephen Phillips; Stefan Seregard; Hans E. Grossniklaus
TAGS: cohort studies, digital image analysis, digital immunoassays, gene expression, intraocular melanoma, neoplasm metastasis, neoplasms
Trans. Vis. Sci. Tech.. 2019; 8(3):11. doi: https://doi.org/10.1167/tvst.8.3.11

Includes: Supplemental Content

Articles April 2019

Next-Generation Sequencing of Uveal Melanoma for Detection of Genetic Alterations Predicting Metastasis

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Armin R. Afshar; Bertil E. Damato; Jay M. Stewart; Lydia B. Zablotska; Ritu Roy; Adam B. Olshen; Nancy M. Joseph; Boris C. Bastian
TAGS: genetics, intraocular melanoma, massively-parallel genome sequencing, neoplasm metastasis, neoplasms, mutation, chromosomes, human, pair 3, histopathology tests, gene expression profiling
Trans. Vis. Sci. Tech.. 2019; 8(2):18. doi: https://doi.org/10.1167/tvst.8.2.18

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White Paper on Ophthalmic Imaging for Choroidal Nevus Identification and Transformation into Melanoma

Cell-Free DNA Tumor Fraction in the Aqueous Humor Is Associated With Therapeutic Response in Retinoblastoma Patients

Piloting a Deep Learning Model for Predicting Nuclear BAP1 Immunohistochemical Expression of Uveal Melanoma from Hematoxylin-and-Eosin Sections

The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

Comparison of Current Optical Coherence Tomography Angiography Methods in Imaging Retinal Hemangioblastomas

Benzalkonium Chloride Resistance in Staphylococcus epidermidis on the Ocular Surface of Glaucoma Patients Under Long-Term Administration of Eye Drops

Cherenkov Luminescence Imaging for Assessment of Radioactive Plaque Position in Brachytherapy of Uveal Melanoma: An In Vivo Feasibility Study

Characterization of Uveal Melanoma Cell Lines and Primary Tumor Samples in 3D Culture

An Automated Method for Assessing Topographical Structure–Function Agreement in Abnormal Glaucomatous Regions

A Clinician's Guide to Artificial Intelligence: How to Critically Appraise Machine Learning Studies

VEGFR1-Targeted Contrast-Enhanced Ultrasound Imaging Quantification of Vasculogenic Mimicry Microcirculation in a Mouse Model of Choroidal Melanoma

A Panel of Circulating MicroRNAs Detects Uveal Melanoma With High Precision

In Vitro Evaluation of the Inhibitory Effect of Topical Ophthalmic Agents on Acanthamoeba Viability

Magnetic Hyperthermia in Y79 Retinoblastoma and ARPE-19 Retinal Epithelial Cells: Tumor Selective Apoptotic Activity of Iron Oxide Nanoparticle

The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

In Vitro Effect of Toluidine Blue Antimicrobial Photodynamic Chemotherapy on Staphylococcus epidermidis and Staphylococcus aureus Isolated from Ocular Surface Infection

Smartphone-Based, Rapid, Wide-Field Fundus Photography for Diagnosis of Pediatric Retinal Diseases

Detection of Malignancy in Ocular Surface Lesions by Inverse Spectroscopic Optical Coherence Tomography and Two-Photon Autofluorescence

Digital Image Analysis of BAP-1 Accurately Predicts Uveal Melanoma Metastasis

Next-Generation Sequencing of Uveal Melanoma for Detection of Genetic Alterations Predicting Metastasis

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