Pharmacology

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Retina August 2024

Retinal Penetrating Adeno-Associated Virus

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Binit Kumar; Manish Mishra; Siobhan Cashman; Rajendra Kumar-Singh
TAGS: adeno-associated virus, capsid, green fluorescent proteins, injections, intravitreal injections, mice, oxidative stress, peptides, photoreceptors, proteins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):30. https://doi.org/10.1167/iovs.65.10.30

Includes: Multimedia, Supplemental Content

Letters to the Editor August 2024

Causal Association Between Lipid-Lowering Drugs and Glaucoma: A Drug-Targeted Mendelian Randomization Study

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Yaqiong Liu; Tao Li
TAGS: antilipemic agents, glaucoma, lipid-lowering therapy, mendelian randomization analysis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):23. https://doi.org/10.1167/iovs.65.10.23

Includes: Supplemental Content

Neuro-ophthalmology August 2024

Effects of Topic Delivery of an Inhibitor of Serine Racemase on Laser-Induced Choroidal Vasculopathy

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Simin Wang; Yu Liu; Dehuan Xu; Kaifan Pei; Haiyan Jiang; Li Gong; Wen Zeng; Yimei Liu; Shengzhou Wu
TAGS: choroidal neovascularization, eyedrops, fluorescein, lasers, mice, serine, vascular diseases, bevacizumab
Trans. Vis. Sci. Tech.. 2024; 13(8):24. https://doi.org/10.1167/tvst.13.8.24

Includes: Supplemental Content

Cornea & External Disease August 2024

Effect of Topical Losartan in the Treatment of Established Corneal Fibrosis in Rabbits

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Valeria Villabona Martinez; Barbara Araujo Lima Dutra; Marcony R. Santhiago; Steven E. Wilson
TAGS: cornea, fibrosis, losartan, oryctolagus cuniculus
Trans. Vis. Sci. Tech.. 2024; 13(8):22. https://doi.org/10.1167/tvst.13.8.22

Retina August 2024

Subthreshold Micropulse Laser Versus Oral Spironolactone in Chronic Central Serous Chorioretinopathy: A Quasi-Randomized Controlled Trial

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Sheng Gao; Ge Ge; Yun Zhang; Meixia Zhang
TAGS: central serous chorioretinopathy, lasers, spironolactone
Trans. Vis. Sci. Tech.. 2024; 13(8):19. https://doi.org/10.1167/tvst.13.8.19

Includes: Supplemental Content

Genetics August 2024

Identification of Potential Drug Targets for Myopia Through Mendelian Randomization

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Yimin Qin; Chengcheng Lei; Tianfeng Lin; Xiaotong Han; Decai Wang
TAGS: drug delivery systems, genes, mendelian randomization analysis, myopia, proteins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):13. https://doi.org/10.1167/iovs.65.10.13

Includes: Supplemental Content

Retina August 2024

IL-23 Priming Enhances the Neuroprotective Effects of MSC-Derived Exosomes in Treating Retinal Degeneration

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Hong Zhou; Yan Liu; Tian Zhou; Ziqi Yang; Biyan Ni; Yang Zhou; Huiyi Xu; Xiaojing Lin; Shiya Lin; Chang He; Xialin Liu
TAGS: exosomes, interleukin-23, mesenchymal stem cells, micrornas, neuroprotective effect, retinal degeneration, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):8. https://doi.org/10.1167/iovs.65.10.8

Includes: Supplemental Content

Article August 2024

Prospective control of steering through multiple waypoints

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A. J. Jansen; Brett R. Fajen
TAGS: gaze, heterogeneity of variance, mephedrone, unmanned aerial devices, high-velocity thrust technique, eye-tracking, performance measures, joystick, eye movement
Journal of Vision. 2024; 24(8):1. https://doi.org/10.1167/jov.24.8.1

Includes: Multimedia, Supplemental Content

Retina July 2024

Blood Glucose Levels Moderate the Associations Between IGF-1 Levels and Choroidal Metrics in Patients With Diabetes With Acromegaly Without Diabetic Retinopathy

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Xia Zhang; Heng Wang; Kai Zhang; Jin Ma; Huijing He; Shuang Song; Enhua Shao; Bo Chen; Jingyuan Yang; Xinyu Zhao; Wenda Sui; Meng Wang; Sihua Liu; Xiaopeng Guo; Huijuan Zhu; Yong Yao; Yong Zhong; Bing Xing
TAGS: acromegaly, blood glucose, diabetes mellitus, diabetes mellitus, type 2, insulin-like growth factor i, diabetic retinopathy, antidepressive agents, tricyclic, trichloroacetic acid
Trans. Vis. Sci. Tech.. 2024; 13(7):20. https://doi.org/10.1167/tvst.13.7.20

Includes: Supplemental Content

Article July 2024

Instruction alters the influence of allocentric landmarks in a reach task

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Lina Musa; Xiaogang Yan; J. Douglas Crawford
TAGS: allopurinol, ego, teaching, visual fields, precision, musa plant
Journal of Vision. 2024; 24(7):17. https://doi.org/10.1167/jov.24.7.17

Retina July 2024

Long-Term Effects of Intravitreal Ranibizumab Compared With Panretinal Photocoagulation on Optical Coherence Tomography Measured Choroidal Thickness and Vascularity

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Brian Lee; Kristin Josic; Muneeswar G. Nittala; Swetha B. Velaga; Ayesha Karamat; Sowmya Srinivas; Federico Corvi; Gagan Singh; Srinivas Sadda; Jennifer K. Sun; Michael Ip; for the DRCR Retina Network
TAGS: optical coherence tomography, panretinal photocoagulation, ranibizumab, cortical blindness, eye, cardiovascular imaging, significance
Trans. Vis. Sci. Tech.. 2024; 13(7):19. https://doi.org/10.1167/tvst.13.7.19

Includes: Supplemental Content

Article July 2024

Super recognizers: Increased sensitivity or reduced biases? Insights from serial dependence

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Fiammetta Marini; Mauro Manassi; Meike Ramon
TAGS: face, russell-silver syndrome, shape, somatostatin receptor scintigraphy, morphine, dog, domestic
Journal of Vision. 2024; 24(7):13. https://doi.org/10.1167/jov.24.7.13

Retina July 2024

Real-World Use of Off-Label MVASI in the Treatment of Patients With Neovascular AMD and DME

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Marco Lombardo; Filippo Missiroli; Luca Cerri; Roberto P. Sorge; Massimo Cesareo; Federico Ricci
TAGS: bevacizumab, bevacizumab-awwb, exudative age-related macular degeneration, off-label use, biosimilar pharmaceuticals, injections
Trans. Vis. Sci. Tech.. 2024; 13(7):17. https://doi.org/10.1167/tvst.13.7.17

Retina July 2024

Lipid Nanoparticle-Mediated Delivery of mRNA Into the Mouse and Human Retina and Other Ocular Tissues

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Cheri Z. Chambers; Gillian L. Soo; Abbi L. Engel; Ian A. Glass; the Birth Defects Research Laboratory (BDRL); Andrea Frassetto; Paolo G. V. Martini; Timothy J. Cherry
TAGS: lipid nanoparticles, mice, retina, rna, messenger, lipids, body tissue
Trans. Vis. Sci. Tech.. 2024; 13(7):7. https://doi.org/10.1167/tvst.13.7.7

Includes: Supplemental Content

Retina July 2024

Viscoelastic, Optical, and Surgical Properties of Vitreous Body Replacement Hydrogels After Aging Compared to Porcine Vitreous Bodies And Silicone Oils

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Maximilian Hammer; Marcel Muuss; Lorenz Herbster; Jonathan Herth; Alexander Scheuerle; Ramin Khoramnia; Grzegorz Łabuz; Philipp Uhl; Gerd Uwe Auffarth
TAGS: aging, gel, hydrogels, injections, optics, silicone oils, suidae, surgical procedures, operative, vitreous body, tetracycline
Trans. Vis. Sci. Tech.. 2024; 13(7):5. https://doi.org/10.1167/tvst.13.7.5

Retina June 2024

Unveiling Statins and Genetics in Age-Related Macular Degeneration: The Coimbra Eye Study—Report 9

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Patrícia Barreto; Cláudia Farinha; Rita Coimbra; Maria Luz Cachulo; Joana Barbosa Melo; Yara Lechanteur; Carel B. Hoyng; José Cunha-Vaz; Rufino Silva
TAGS: age-related macular degeneration, eye, statins, genetics, study report
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):38. https://doi.org/10.1167/iovs.65.6.38

Retina June 2024

Cytokine Levels in Experimental Branch Retinal Vein Occlusion Treated With Either Bevacizumab or Triamcinolone Acetonide

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Ian L. McAllister; Sarojini Vijayasekaran; Samuel McLenachan; Riyaz Bhikoo; Fred K. Chen; Dan Zhang; Emily Kanagalingam; Dao-Yi Yu
TAGS: bevacizumab, cytokine, did not receive therapy or drug, eye, genes, proteins, rna, messenger, triamcinolone acetonide, vascular endothelial growth factor a, venous retinal branch occlusion
Trans. Vis. Sci. Tech.. 2024; 13(6):13. https://doi.org/10.1167/tvst.13.6.13

Cornea & External Disease June 2024

Development and Characterization of a Photocrosslinkable, Chitosan-Based, Nerve Growth Factor–Eluting Hydrogel for the Ocular Surface

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Levi N. Kanu; Amy E. Ross; Wissam Farhat; Sushma V. Mudigunda; Nikolay Boychev; Liangju Kuang; Audrey E. K. Hutcheon; Joseph B. Ciolino
TAGS: cenegermin, chitosan, hydrogel, hydrogels, nerve growth factors, ocular surfaces, drug release
Trans. Vis. Sci. Tech.. 2024; 13(6):12. https://doi.org/10.1167/tvst.13.6.12

Artificial Intelligence June 2024

Deep Neural Networks for Automated Outer Plexiform Layer Subsidence Detection on Retinal OCT of Patients With Intermediate AMD

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Guilherme Aresta; Teresa Araujo; Gregor S. Reiter; Julia Mai; Sophie Riedl; Christoph Grechenig; Robyn H. Guymer; Zhichao Wu; Ursula Schmidt-Erfurth; Hrvoje Bogunovic
TAGS: biological markers, datasets, lead, volume, eye, deep learning
Trans. Vis. Sci. Tech.. 2024; 13(6):7. https://doi.org/10.1167/tvst.13.6.7

Clinical and Epidemiologic Research June 2024

Use of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients With Type 2 Diabetes and the Incidence of Retinal Vein Occlusion in Taiwan

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Hou-Ren Tsai; Yu-Jie Lin; Jih-I Yeh; Shu-Man Lin; Peter Pin-Sung Liu; Yung-Ching Chang; Yuan-Chieh Lee; Ching-Hui Loh; Huei-Kai Huang
TAGS: diabetes mellitus, type 2, retinal vein occlusion, sodium-glucose transport proteins, taiwan, sodium-glucose transporter 2 inhibitors, incidence
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):19. https://doi.org/10.1167/iovs.65.6.19

Includes: Supplemental Content

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Retinal Penetrating Adeno-Associated Virus

Causal Association Between Lipid-Lowering Drugs and Glaucoma: A Drug-Targeted Mendelian Randomization Study

Effects of Topic Delivery of an Inhibitor of Serine Racemase on Laser-Induced Choroidal Vasculopathy

Effect of Topical Losartan in the Treatment of Established Corneal Fibrosis in Rabbits

Subthreshold Micropulse Laser Versus Oral Spironolactone in Chronic Central Serous Chorioretinopathy: A Quasi-Randomized Controlled Trial

Identification of Potential Drug Targets for Myopia Through Mendelian Randomization

IL-23 Priming Enhances the Neuroprotective Effects of MSC-Derived Exosomes in Treating Retinal Degeneration

Prospective control of steering through multiple waypoints

Blood Glucose Levels Moderate the Associations Between IGF-1 Levels and Choroidal Metrics in Patients With Diabetes With Acromegaly Without Diabetic Retinopathy

Instruction alters the influence of allocentric landmarks in a reach task

Long-Term Effects of Intravitreal Ranibizumab Compared With Panretinal Photocoagulation on Optical Coherence Tomography Measured Choroidal Thickness and Vascularity

Super recognizers: Increased sensitivity or reduced biases? Insights from serial dependence

Real-World Use of Off-Label MVASI in the Treatment of Patients With Neovascular AMD and DME

Lipid Nanoparticle-Mediated Delivery of mRNA Into the Mouse and Human Retina and Other Ocular Tissues

Viscoelastic, Optical, and Surgical Properties of Vitreous Body Replacement Hydrogels After Aging Compared to Porcine Vitreous Bodies And Silicone Oils

Unveiling Statins and Genetics in Age-Related Macular Degeneration: The Coimbra Eye Study—Report 9

Cytokine Levels in Experimental Branch Retinal Vein Occlusion Treated With Either Bevacizumab or Triamcinolone Acetonide

Development and Characterization of a Photocrosslinkable, Chitosan-Based, Nerve Growth Factor–Eluting Hydrogel for the Ocular Surface

Deep Neural Networks for Automated Outer Plexiform Layer Subsidence Detection on Retinal OCT of Patients With Intermediate AMD

Use of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients With Type 2 Diabetes and the Incidence of Retinal Vein Occlusion in Taiwan

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