Pharmacology

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Articles January 2019

Intraocular Pressure Effects and Mechanism of Action of Topical Versus Sustained-Release Bimatoprost

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Susan S. Lee; Alexandra Almazan; Sherri Decker; Yan Zhong; Alazar N. Ghebremeskel; Patrick Hughes; Michael R. Robinson; James A. Burke; Robert N. Weinreb
TAGS: intraocular pressure, pharmacokinetics, bimatoprost
Trans. Vis. Sci. Tech.. 2019; 8(1):15. doi: 10.1167/tvst.8.1.15

Articles January 2019

Characterization of Biodegradable Microsphere-Hydrogel Ocular Drug Delivery System for Controlled and Extended Release of Ranibizumab

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Wenqiang Liu; Marta Arias Borrell; David C. Venerus; William F. Mieler; Jennifer J. Kang-Mieler
TAGS: hydrogel, hydrogels, edema, temperature, ranibizumab, body temperature, drug delivery systems, microspheres
Trans. Vis. Sci. Tech.. 2019; 8(1):12. doi: 10.1167/tvst.8.1.12

Articles January 2019

Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

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Joseph D. Bogaard; Jonathon B. Young; Asad Movahedan; Iris S. Kassem
TAGS: enoxaparin, child, animal model, triamcinolone, eye, fibrin, therapeutic intervention, oryctolagus cuniculus, postoperative care, anterior chamber of eye, inflammation, enzyme-linked immunosorbent assay, did not receive therapy or drug
Trans. Vis. Sci. Tech.. 2019; 8(1):5. doi: 10.1167/tvst.8.1.5

Articles December 2018

Quantitative Analysis of Changes to Meibomian Gland Morphology Due to S-1 Chemotherapy

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Kazuyoshi Ohtomo; Reiko Arita; Rika Shirakawa; Tomohiko Usui; Hiroharu Yamashita; Yasuyuki Seto; Satoru Yamagami; for the TS-1 Multicenter Study Group
TAGS: eyelid, meibomian gland, chemotherapy regimen, language morphology, morphology
Trans. Vis. Sci. Tech.. 2018; 7(6):37. doi: 10.1167/tvst.7.6.37

Articles December 2018

Retinal Toxicity of Intravitreal Injection of Ziv-Aflibercept in Albino Rabbits

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Dan Ramon; Jonathan Shahar; Amir Massarweh; Irit Man; Ido Perlman; Anat Loewenstein
TAGS: albinism, glial fibrillary acidic protein, eye, retina, retinal toxicity, intravitreal injections, ziv-aflibercept, electroretinography, oryctolagus cuniculus
Trans. Vis. Sci. Tech.. 2018; 7(6):23. doi: 10.1167/tvst.7.6.23

Articles November 2018

Composition and Comparison of the Ocular Surface Microbiome in Infants and Older Children

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Kara M. Cavuoto; Santanu Banerjee; Darlene Miller; Anat Galor
TAGS: child, infant, eye, microbiome
Trans. Vis. Sci. Tech.. 2018; 7(6):16. doi: 10.1167/tvst.7.6.16

Includes: Supplemental Content

Articles August 2018

A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

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Nobuo Machinaga; Gary W. Ashley; Ralph Reid; Atsushi Yamasaki; Kyosuke Tanaka; Koichi Nakamura; Yoshiyuki Yabe; Yasushi Yoshigae; Daniel V. Santi
TAGS: half-life, injections, oryctolagus cuniculus, vitreous body, eye, molecule
Trans. Vis. Sci. Tech.. 2018; 7(4):21. doi: 10.1167/tvst.7.4.21

Includes: Supplemental Content

Articles April 2018

Inhibitory Effects of Angiotensin II Receptor Blockade on Human Tenon Fibroblast Migration and Reactive Oxygen Species Production in Cell Culture

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Duri Kim; Ushasree Pattamatta; Elizabeth Kelly; Paul R. Healey; Nicole Carnt; Hans Zoellner; Andrew J. R. White
TAGS: angiotensins, irbesartan, cell culture techniques, receptor, angiotensin ii, angiotensin ii, fibroblasts, cell count, reactive oxygen species
Trans. Vis. Sci. Tech.. 2018; 7(2):20. doi: 10.1167/tvst.7.2.20

Editorial March 2018

Reviewers

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TAGS: betula genus, burns, limb, hispanics or latinos, kenya, steel, technology, tolnaftate, vision, fingers, silver, hematoma of pinna, liposomal amikacin for inhalation
Trans. Vis. Sci. Tech.. 2018; 7(2):r. doi: 10.1167/tvst.7.2.r

Articles October 2017

Evaluation of a Sustained-Release Prednisolone Acetate Biodegradable Subconjunctival Implant in a Non-Human Primate Model

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Yu-Chi Liu; Anthony Herr Cheun Ng; Xu Wen Ng; Peng Yan; Subbu S. Venkatraman; Jodhbir S. Mehta; Tina T. Wong
TAGS: acetates, plasma, prednisolone, primates, eye, hematology, toxicokinetics, implantation procedure, histopathology tests, implants
Trans. Vis. Sci. Tech.. 2017; 6(5):9. doi: 10.1167/tvst.6.5.9

Includes: Supplemental Content

Articles March 2017

Time-Dependent Decline in Multifocal Electroretinogram Requires Faster Recording Procedures in Anesthetized Pigs

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Nina Buus Sørensen; Anders Tolstrup Christiansen; Troels Wesenberg Kjær; Kristian Klemp; Morten la Cour; Jens Folke Kiilgaard
TAGS: anesthetics, electroretinography, injection of therapeutic agent, isoflurane, propofol, suidae
Trans. Vis. Sci. Tech.. 2017; 6(2):6. doi: 10.1167/tvst.6.2.6

Clinical Trials December 2016

Suprachoroidal Corticosteroid Administration: A Novel Route for Local Treatment of Noninfectious Uveitis

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Debra A. Goldstein; Diana Do; Glenn Noronha; Jennifer M. Kissner; Sunil K. Srivastava; Quan D. Nguyen
TAGS: adrenal corticosteroids, glucocorticoids, injection of therapeutic agent, uveitis, mineralocorticoids
Trans. Vis. Sci. Tech.. 2016; 5(6):14. doi: 10.1167/tvst.5.6.14

Articles December 2016

Endophthalmitis Prophylaxis Using a Single Drop of Thermoresponsive Controlled-Release Microspheres Loaded with Moxifloxacin in a Rabbit Model

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Alex Mammen; Eric G. Romanowski; Morgan V. Fedorchak; Deepinder K. Dhaliwal; R. M. Shanks; Regis P. Kowalski
TAGS: endophthalmitis, microspheres, oryctolagus cuniculus, moxifloxacin, prevention
Trans. Vis. Sci. Tech.. 2016; 5(6):12. doi: 10.1167/tvst.5.6.12

Articles November 2016

Release of Moxifloxacin from Contact Lenses Using an In Vitro Eye Model: Impact of Artificial Tear Fluid Composition and Mechanical Rubbing

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Chau-Minh Phan; Magdalena Bajgrowicz-Cieslak; Lakshman N. Subbaraman; Lyndon Jones
TAGS: capillary leak syndrome, contact lenses, de lange syndrome, lens, crystalline, lens (device), eye, moxifloxacin, drug release, painful bladder syndrome
Trans. Vis. Sci. Tech.. 2016; 5(6):3. doi: 10.1167/tvst.5.6.3

Articles September 2016

The Accuracy and Reliability of Crowdsource Annotations of Digital Retinal Images

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Danny Mitry; Kris Zutis; Baljean Dhillon; Tunde Peto; Shabina Hayat; Kay-Tee Khaw; James E. Morgan; Wendy Moncur; Emanuele Trucco; Paul J. Foster; 1 for the UK Biobank Eye and Vision Consortium
TAGS: roc curve, reliability, training, consensus, crowdsourcing
Trans. Vis. Sci. Tech.. 2016; 5(5):6. doi: 10.1167/tvst.5.5.6

Includes: Supplemental Content

Articles August 2016

Retinal Arterioles in Hypo-, Normo-, and Hypertensive Subjects Measured Using Adaptive Optics

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Jacob G. Hillard; Thomas J. Gast; Toco Y.P. Chui; Dan Sapir; Stephen A. Burns
TAGS: hypertension, arteriole, optics, diagnostic imaging
Trans. Vis. Sci. Tech.. 2016; 5(4):16. doi: 10.1167/tvst.5.4.16

New Developments in Vision Research July 2016

Selected Antimicrobial Activity of Topical Ophthalmic Anesthetics

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Margaret M. Reynolds; Kerryl E. Greenwood-Quaintance; Robin Patel; Jose S. Pulido
TAGS: lidocaine, anesthetics, endophthalmitis, povidone-iodine, eye, tetracaine, anesthetics, topical, proparacaine, antimicrobial activity, benzalkonium chloride
Trans. Vis. Sci. Tech.. 2016; 5(4):2. doi: 10.1167/tvst.5.4.2

Articles March 2016

A Drug Delivery System for Administration of Anti–TNF-α Antibody

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Marie-Claude Robert; Mathieu Frenette; Chengxin Zhou; Yueran Yan; James Chodosh; Frederick A. Jakobiec; Anna M. Stagner; Demetrios Vavvas; Claes H. Dohlman; Eleftherios I. Paschalis
TAGS: tumor necrosis factors, drug delivery systems, antibodies, infliximab
Trans. Vis. Sci. Tech.. 2016; 5(2):11. doi: 10.1167/tvst.5.2.11

Includes: Supplemental Content

Articles September 2015

The Effect of Transient Local Anti-inflammatory Treatment on the Survival of Pig Retinal Progenitor Cell Allotransplants

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Murilo Abud; Petr Baranov; Caroline Hicks; Sara Patel; Burke Lieppman; Caio Regatieri; John Sinden; David Isaac; Marcos Avila; Michael Young
TAGS: anti-inflammatory agents, stem cells, photoreceptors, prpc proteins, reverse transcriptase polymerase chain reaction, rhodopsin, transplantation, homologous, therapeutic immunosuppression, transplantation, immunocytochemistry
Trans. Vis. Sci. Tech.. 2015; 4(5):6. doi: 10.1167/tvst.4.5.6

Includes: Supplemental Content

Articles June 2015

Natural Bioadhesive Biodegradable Nanoparticle-Based Topical Ophthalmic Formulations for Management of Glaucoma

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Mohammed Mostafa Ibrahim; Abd-Elgawad Helmy Abd-Elgawad; Osama Abd-Elazeem Soliman; Monica M. Jablonski
TAGS: glaucoma, eye, eyedrops, brimonidine, nanoparticles
Trans. Vis. Sci. Tech.. 2015; 4(3):12. doi: 10.1167/tvst.4.3.12

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Intraocular Pressure Effects and Mechanism of Action of Topical Versus Sustained-Release Bimatoprost

Characterization of Biodegradable Microsphere-Hydrogel Ocular Drug Delivery System for Controlled and Extended Release of Ranibizumab

Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

Quantitative Analysis of Changes to Meibomian Gland Morphology Due to S-1 Chemotherapy

Retinal Toxicity of Intravitreal Injection of Ziv-Aflibercept in Albino Rabbits

Composition and Comparison of the Ocular Surface Microbiome in Infants and Older Children

A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

Inhibitory Effects of Angiotensin II Receptor Blockade on Human Tenon Fibroblast Migration and Reactive Oxygen Species Production in Cell Culture

Reviewers

Evaluation of a Sustained-Release Prednisolone Acetate Biodegradable Subconjunctival Implant in a Non-Human Primate Model

Time-Dependent Decline in Multifocal Electroretinogram Requires Faster Recording Procedures in Anesthetized Pigs

Suprachoroidal Corticosteroid Administration: A Novel Route for Local Treatment of Noninfectious Uveitis

Endophthalmitis Prophylaxis Using a Single Drop of Thermoresponsive Controlled-Release Microspheres Loaded with Moxifloxacin in a Rabbit Model

Release of Moxifloxacin from Contact Lenses Using an In Vitro Eye Model: Impact of Artificial Tear Fluid Composition and Mechanical Rubbing

The Accuracy and Reliability of Crowdsource Annotations of Digital Retinal Images

Retinal Arterioles in Hypo-, Normo-, and Hypertensive Subjects Measured Using Adaptive Optics

Selected Antimicrobial Activity of Topical Ophthalmic Anesthetics

A Drug Delivery System for Administration of Anti–TNF-α Antibody

The Effect of Transient Local Anti-inflammatory Treatment on the Survival of Pig Retinal Progenitor Cell Allotransplants

Natural Bioadhesive Biodegradable Nanoparticle-Based Topical Ophthalmic Formulations for Management of Glaucoma

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