Pharmacology

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Editorial August 2019

The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

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Marco Zarbin
TAGS: peer review, science
Trans. Vis. Sci. Tech.. 2019; 8(4):r. doi: 10.1167/tvst.8.4.r

New Developments in Vision Research June 2019

In Vitro Antimicrobial Efficacy of Silver Lens Cases Used With a Multipurpose Disinfecting Solution

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Ananya Datta; Mark Willcox; Fiona Stapleton
TAGS: antimicrobials, contact lens storage case, disinfection, silver, contact lenses
Trans. Vis. Sci. Tech.. 2019; 8(3):52. doi: 10.1167/tvst.8.3.52

Articles June 2019

Controlled Release of Vancomycin From a Thermoresponsive Hydrogel System for the Prophylactic Treatment of Postoperative Acute Endophthalmitis

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Emily Dosmar; Wenqiang Liu; Geeya Patel; Alison Rogozinski; William F. Mieler; Jennifer J. Kang-Mieler
TAGS: endophthalmitis, hydrogel, vancomycin, infection, postoperative care, prevention, injections, saline solutions
Trans. Vis. Sci. Tech.. 2019; 8(3):53. doi: 10.1167/tvst.8.3.53

Review June 2019

Sleep–Wake Disturbance Related to Ocular Disease: A Systematic Review of Phase-Shifting Pharmaceutical Therapies

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Colm D. Andrews; Russell G. Foster; Iona Alexander; Sridhar Vasudevan; Susan M. Downes; Carl Heneghan; Annette Plüddemann
TAGS: eye diseases, melatonin, pharmacy (field), sleep, systematic reviews, tasimelteon
Trans. Vis. Sci. Tech.. 2019; 8(3):49. doi: 10.1167/tvst.8.3.49

Includes: Supplemental Content

Articles June 2019

In Vitro Effect of Toluidine Blue Antimicrobial Photodynamic Chemotherapy on Staphylococcus epidermidis and Staphylococcus aureus Isolated from Ocular Surface Infection

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Jing Shen; Qingfeng Liang; Guanyu Su; Yang Zhang; Zhiqun Wang; Christophe Baudouin; Antoine Labbé
TAGS: antimicrobials, chemotherapy regimen, infection, mass or substance concentration per volume, staphylococcus aureus, staphylococcus epidermidis, tolonium chloride, bacteria, anti-bacterial agents, photosensitizing agents
Trans. Vis. Sci. Tech.. 2019; 8(3):45. doi: 10.1167/tvst.8.3.45

Clinical Trials June 2019

Effects of the Glaucoma Drugs Latanoprost and Brimonidine on Corneal Temperature

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Katarzyna Konieczka; Simone Koch; Daniela Hauenstein; Thomas Navin Chackathayil; Tatjana Binggeli; Andreas Schoetzau; Josef Flammer
TAGS: brimonidine, latanoprost, antiglaucoma medications, cornea, temperature
Trans. Vis. Sci. Tech.. 2019; 8(3):47. doi: 10.1167/tvst.8.3.47

Articles June 2019

Human Lacrimal Production Rate and Wetted Length of Modified Schirmer's Tear Test Strips

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Young Hyun Kim; Andrew D. Graham; Wing Li; Clayton J. Radke; Meng C. Lin
TAGS: evaporation, eye, heterogeneity of variance, loa, sample size, tear production, dry eye syndromes, humidity, reading (activity), anesthetics
Trans. Vis. Sci. Tech.. 2019; 8(3):40. doi: 10.1167/tvst.8.3.40

Articles June 2019

Evaluation of Liposomal and Conventional Amphotericin B in Experimental Fungal Keratitis Rabbit Model

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Anup Kumar Ghosh; Shivaprakash Mandya Rudramurthy; Amit Gupta; Hansraj Choudhary; Shreya Singh; Anchal Thakur; Manu Jatana
TAGS: amphotericin b, antifungal agents, cornea, did not receive therapy or drug, fungal keratitis, liposomes, oryctolagus cuniculus, keratitis
Trans. Vis. Sci. Tech.. 2019; 8(3):35. doi: 10.1167/tvst.8.3.35

Articles June 2019

Tracking the Reflective Light Particles Spreading on the Cornea: An Emerging Assessment for Tear Film Homeostasis

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Hung-Yin Lai; Ming-Tse Kuo; Po-Chiung Fang; Chi-Chang Lin; Chun-Chih Chien; Wan-Hua Cho; Alexander Chen; Ing-Chou Lai
TAGS: homeostasis, cornea, tear film finding, liposomal amikacin for inhalation
Trans. Vis. Sci. Tech.. 2019; 8(3):32. doi: 10.1167/tvst.8.3.32

Includes: Multimedia, Supplemental Content

Articles May 2019

Hydrofluoric Acid and Other Impurities in Toxic Perfluorooctane Batches

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Dirk-Henning Menz; Nicolas Feltgen; Thorsten Lechner; Helge Menz; Bernd-Kristof Müller; Joachim Dresp; Hans Hoerauf
TAGS: olive oil, heart failure, patent foramen ovale, hydrofluoric acid, gas chromatography-mass spectrometry, body tissue, toxic effect, retinal toxicity, catabolism, perfluorooctane
Trans. Vis. Sci. Tech.. 2019; 8(3):24. doi: 10.1167/tvst.8.3.24

Clinical Trials May 2019

A Phase I/II Placebo-Controlled Randomized Pilot Clinical Trial of Recombinant Deoxyribonuclease (DNase) Eye Drops Use in Patients With Dry Eye Disease

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Christine Mun; Shilpa Gulati; Sapna Tibrewal; Yi-Fan Chen; Seungwon An; Bayasgalan Surenkhuu; Ilangovan Raju; Morgan Buwick; Anna Ahn; Ji-Eun Kwon; Nour Atassi; Anubhav Pradeep; Damiano Rondelli; Sandeep Jain
TAGS: deoxyribonuclease i, deoxyribonucleases, dry eye syndromes, placebos, eyedrops
Trans. Vis. Sci. Tech.. 2019; 8(3):10. doi: 10.1167/tvst.8.3.10

Articles January 2019

Intraocular Pressure Effects and Mechanism of Action of Topical Versus Sustained-Release Bimatoprost

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Susan S. Lee; Alexandra Almazan; Sherri Decker; Yan Zhong; Alazar N. Ghebremeskel; Patrick Hughes; Michael R. Robinson; James A. Burke; Robert N. Weinreb
TAGS: intraocular pressure, pharmacokinetics, bimatoprost
Trans. Vis. Sci. Tech.. 2019; 8(1):15. doi: 10.1167/tvst.8.1.15

Articles January 2019

Characterization of Biodegradable Microsphere-Hydrogel Ocular Drug Delivery System for Controlled and Extended Release of Ranibizumab

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Wenqiang Liu; Marta Arias Borrell; David C. Venerus; William F. Mieler; Jennifer J. Kang-Mieler
TAGS: hydrogel, hydrogels, edema, temperature, ranibizumab, body temperature, drug delivery systems, microspheres
Trans. Vis. Sci. Tech.. 2019; 8(1):12. doi: 10.1167/tvst.8.1.12

Articles January 2019

Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

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Joseph D. Bogaard; Jonathon B. Young; Asad Movahedan; Iris S. Kassem
TAGS: enoxaparin, child, animal model, triamcinolone, eye, fibrin, therapeutic intervention, oryctolagus cuniculus, postoperative care, anterior chamber of eye
Trans. Vis. Sci. Tech.. 2019; 8(1):5. doi: 10.1167/tvst.8.1.5

Articles December 2018

Quantitative Analysis of Changes to Meibomian Gland Morphology Due to S-1 Chemotherapy

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Kazuyoshi Ohtomo; Reiko Arita; Rika Shirakawa; Tomohiko Usui; Hiroharu Yamashita; Yasuyuki Seto; Satoru Yamagami; for the TS-1 Multicenter Study Group
TAGS: eyelid, meibomian gland, chemotherapy regimen, language morphology, morphology
Trans. Vis. Sci. Tech.. 2018; 7(6):37. doi: 10.1167/tvst.7.6.37

Articles December 2018

Retinal Toxicity of Intravitreal Injection of Ziv-Aflibercept in Albino Rabbits

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Dan Ramon; Jonathan Shahar; Amir Massarweh; Irit Man; Ido Perlman; Anat Loewenstein
TAGS: albinism, glial fibrillary acidic protein, eye, retina, retinal toxicity, intravitreal injections, ziv-aflibercept, electroretinography, oryctolagus cuniculus
Trans. Vis. Sci. Tech.. 2018; 7(6):23. doi: 10.1167/tvst.7.6.23

Articles November 2018

Composition and Comparison of the Ocular Surface Microbiome in Infants and Older Children

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Kara M. Cavuoto; Santanu Banerjee; Darlene Miller; Anat Galor
TAGS: child, infant, eye, microbiome
Trans. Vis. Sci. Tech.. 2018; 7(6):16. doi: 10.1167/tvst.7.6.16

Includes: Supplemental Content

Articles August 2018

A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

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Nobuo Machinaga; Gary W. Ashley; Ralph Reid; Atsushi Yamasaki; Kyosuke Tanaka; Koichi Nakamura; Yoshiyuki Yabe; Yasushi Yoshigae; Daniel V. Santi
TAGS: half-life, injections, oryctolagus cuniculus, vitreous body, eye, molecule
Trans. Vis. Sci. Tech.. 2018; 7(4):21. doi: 10.1167/tvst.7.4.21

Includes: Supplemental Content

Articles April 2018

Inhibitory Effects of Angiotensin II Receptor Blockade on Human Tenon Fibroblast Migration and Reactive Oxygen Species Production in Cell Culture

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Duri Kim; Ushasree Pattamatta; Elizabeth Kelly; Paul R. Healey; Nicole Carnt; Hans Zoellner; Andrew J. R. White
TAGS: angiotensins, irbesartan, cell culture techniques, receptor, angiotensin ii, angiotensin ii, fibroblasts, cell count, reactive oxygen species
Trans. Vis. Sci. Tech.. 2018; 7(2):20. doi: 10.1167/tvst.7.2.20

Editorial March 2018

Reviewers

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TAGS: betula genus, burns, limb, hispanics or latinos, kenya, steel, technology, tolnaftate, vision, fingers
Trans. Vis. Sci. Tech.. 2018; 7(2):r. doi: 10.1167/tvst.7.2.r

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The Elusive Nature of Truth in Scientific Studies and the Importance of Peer Review

In Vitro Antimicrobial Efficacy of Silver Lens Cases Used With a Multipurpose Disinfecting Solution

Controlled Release of Vancomycin From a Thermoresponsive Hydrogel System for the Prophylactic Treatment of Postoperative Acute Endophthalmitis

Sleep–Wake Disturbance Related to Ocular Disease: A Systematic Review of Phase-Shifting Pharmaceutical Therapies

In Vitro Effect of Toluidine Blue Antimicrobial Photodynamic Chemotherapy on Staphylococcus epidermidis and Staphylococcus aureus Isolated from Ocular Surface Infection

Effects of the Glaucoma Drugs Latanoprost and Brimonidine on Corneal Temperature

Human Lacrimal Production Rate and Wetted Length of Modified Schirmer's Tear Test Strips

Evaluation of Liposomal and Conventional Amphotericin B in Experimental Fungal Keratitis Rabbit Model

Tracking the Reflective Light Particles Spreading on the Cornea: An Emerging Assessment for Tear Film Homeostasis

Hydrofluoric Acid and Other Impurities in Toxic Perfluorooctane Batches

A Phase I/II Placebo-Controlled Randomized Pilot Clinical Trial of Recombinant Deoxyribonuclease (DNase) Eye Drops Use in Patients With Dry Eye Disease

Intraocular Pressure Effects and Mechanism of Action of Topical Versus Sustained-Release Bimatoprost

Characterization of Biodegradable Microsphere-Hydrogel Ocular Drug Delivery System for Controlled and Extended Release of Ranibizumab

Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy

Quantitative Analysis of Changes to Meibomian Gland Morphology Due to S-1 Chemotherapy

Retinal Toxicity of Intravitreal Injection of Ziv-Aflibercept in Albino Rabbits

Composition and Comparison of the Ocular Surface Microbiome in Infants and Older Children

A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

Inhibitory Effects of Angiotensin II Receptor Blockade on Human Tenon Fibroblast Migration and Reactive Oxygen Species Production in Cell Culture

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