Pharmacology

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Articles April 2018

Inhibitory Effects of Angiotensin II Receptor Blockade on Human Tenon Fibroblast Migration and Reactive Oxygen Species Production in Cell Culture

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Duri Kim; Ushasree Pattamatta; Elizabeth Kelly; Paul R. Healey; Nicole Carnt; Hans Zoellner; Andrew J. R. White
TAGS: angiotensins, irbesartan, cell culture techniques, receptor, angiotensin ii, angiotensin ii, fibroblasts, cell count, reactive oxygen species
Trans. Vis. Sci. Tech.. 2018; 7(2):20. doi: 10.1167/tvst.7.2.20

Editorial March 2018

Reviewers

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TAGS: betula genus, burns, limb, hispanics or latinos, kenya, steel, technology, tolnaftate, vision, fingers, silver, hematoma of pinna, liposomal amikacin for inhalation
Trans. Vis. Sci. Tech.. 2018; 7(2):r. doi: 10.1167/tvst.7.2.r

Articles October 2017

Evaluation of a Sustained-Release Prednisolone Acetate Biodegradable Subconjunctival Implant in a Non-Human Primate Model

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Yu-Chi Liu; Anthony Herr Cheun Ng; Xu Wen Ng; Peng Yan; Subbu S. Venkatraman; Jodhbir S. Mehta; Tina T. Wong
TAGS: acetates, plasma, prednisolone, primates, eye, hematology, toxicokinetics, implantation procedure, histopathology tests, implants
Trans. Vis. Sci. Tech.. 2017; 6(5):9. doi: 10.1167/tvst.6.5.9

Includes: Supplemental Content

Articles March 2017

Time-Dependent Decline in Multifocal Electroretinogram Requires Faster Recording Procedures in Anesthetized Pigs

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Nina Buus Sørensen; Anders Tolstrup Christiansen; Troels Wesenberg Kjær; Kristian Klemp; Morten la Cour; Jens Folke Kiilgaard
TAGS: anesthetics, electroretinography, injection of therapeutic agent, isoflurane, propofol, suidae
Trans. Vis. Sci. Tech.. 2017; 6(2):6. doi: 10.1167/tvst.6.2.6

Clinical Trials December 2016

Suprachoroidal Corticosteroid Administration: A Novel Route for Local Treatment of Noninfectious Uveitis

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Debra A. Goldstein; Diana Do; Glenn Noronha; Jennifer M. Kissner; Sunil K. Srivastava; Quan D. Nguyen
TAGS: adrenal corticosteroids, glucocorticoids, injection of therapeutic agent, uveitis, mineralocorticoids
Trans. Vis. Sci. Tech.. 2016; 5(6):14. doi: 10.1167/tvst.5.6.14

Articles December 2016

Endophthalmitis Prophylaxis Using a Single Drop of Thermoresponsive Controlled-Release Microspheres Loaded with Moxifloxacin in a Rabbit Model

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Alex Mammen; Eric G. Romanowski; Morgan V. Fedorchak; Deepinder K. Dhaliwal; R. M. Shanks; Regis P. Kowalski
TAGS: endophthalmitis, microspheres, oryctolagus cuniculus, moxifloxacin, prevention
Trans. Vis. Sci. Tech.. 2016; 5(6):12. doi: 10.1167/tvst.5.6.12

Articles November 2016

Release of Moxifloxacin from Contact Lenses Using an In Vitro Eye Model: Impact of Artificial Tear Fluid Composition and Mechanical Rubbing

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Chau-Minh Phan; Magdalena Bajgrowicz-Cieslak; Lakshman N. Subbaraman; Lyndon Jones
TAGS: capillary leak syndrome, contact lenses, de lange syndrome, lens, crystalline, lens (device), eye, moxifloxacin, drug release, painful bladder syndrome
Trans. Vis. Sci. Tech.. 2016; 5(6):3. doi: 10.1167/tvst.5.6.3

Articles September 2016

The Accuracy and Reliability of Crowdsource Annotations of Digital Retinal Images

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Danny Mitry; Kris Zutis; Baljean Dhillon; Tunde Peto; Shabina Hayat; Kay-Tee Khaw; James E. Morgan; Wendy Moncur; Emanuele Trucco; Paul J. Foster; 1 for the UK Biobank Eye and Vision Consortium
TAGS: roc curve, reliability, training, consensus, crowdsourcing
Trans. Vis. Sci. Tech.. 2016; 5(5):6. doi: 10.1167/tvst.5.5.6

Includes: Supplemental Content

Articles August 2016

Retinal Arterioles in Hypo-, Normo-, and Hypertensive Subjects Measured Using Adaptive Optics

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Jacob G. Hillard; Thomas J. Gast; Toco Y.P. Chui; Dan Sapir; Stephen A. Burns
TAGS: hypertension, arteriole, optics, diagnostic imaging
Trans. Vis. Sci. Tech.. 2016; 5(4):16. doi: 10.1167/tvst.5.4.16

New Developments in Vision Research July 2016

Selected Antimicrobial Activity of Topical Ophthalmic Anesthetics

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Margaret M. Reynolds; Kerryl E. Greenwood-Quaintance; Robin Patel; Jose S. Pulido
TAGS: lidocaine, anesthetics, endophthalmitis, povidone-iodine, eye, tetracaine, anesthetics, topical, proparacaine, antimicrobial activity, benzalkonium chloride
Trans. Vis. Sci. Tech.. 2016; 5(4):2. doi: 10.1167/tvst.5.4.2

Articles March 2016

A Drug Delivery System for Administration of Anti–TNF-α Antibody

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Marie-Claude Robert; Mathieu Frenette; Chengxin Zhou; Yueran Yan; James Chodosh; Frederick A. Jakobiec; Anna M. Stagner; Demetrios Vavvas; Claes H. Dohlman; Eleftherios I. Paschalis
TAGS: tumor necrosis factors, drug delivery systems, antibodies, infliximab
Trans. Vis. Sci. Tech.. 2016; 5(2):11. doi: 10.1167/tvst.5.2.11

Includes: Supplemental Content

Articles September 2015

The Effect of Transient Local Anti-inflammatory Treatment on the Survival of Pig Retinal Progenitor Cell Allotransplants

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Murilo Abud; Petr Baranov; Caroline Hicks; Sara Patel; Burke Lieppman; Caio Regatieri; John Sinden; David Isaac; Marcos Avila; Michael Young
TAGS: anti-inflammatory agents, stem cells, photoreceptors, prpc proteins, reverse transcriptase polymerase chain reaction, rhodopsin, transplantation, homologous, therapeutic immunosuppression, transplantation, immunocytochemistry
Trans. Vis. Sci. Tech.. 2015; 4(5):6. doi: 10.1167/tvst.4.5.6

Includes: Supplemental Content

Articles June 2015

Natural Bioadhesive Biodegradable Nanoparticle-Based Topical Ophthalmic Formulations for Management of Glaucoma

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Mohammed Mostafa Ibrahim; Abd-Elgawad Helmy Abd-Elgawad; Osama Abd-Elazeem Soliman; Monica M. Jablonski
TAGS: glaucoma, eye, eyedrops, brimonidine, nanoparticles
Trans. Vis. Sci. Tech.. 2015; 4(3):12. doi: 10.1167/tvst.4.3.12

Articles June 2015

Topical Ocular Drug Delivery to the Back of the Eye by Mucus-Penetrating Particles

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Lisa R. Schopf; Alexey M. Popov; Elizabeth M. Enlow; James L. Bourassa; Winston Z. Ong; Pawel Nowak; Hongming Chen
TAGS: vascular endothelial growth factor a, administration, topical, drug delivery systems, mucus, oryctolagus cuniculus, swine, miniature, eye
Trans. Vis. Sci. Tech.. 2015; 4(3):11. doi: 10.1167/tvst.4.3.11

Clinical Trials March 2015

One-Year Outcomes of the SAVE Study: S irolimus as a Therapeutic A pproach for U VE itis

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Mohamed A. Ibrahim; Yasir J. Sepah; Anthony Watters; Millena Bittencourt; Erin M. Vigil; Diana V. Do; Quan Dong Nguyen
TAGS: adrenal corticosteroids, rapamycin, glucocorticoids, injection of therapeutic agent, safety, uveitis, visual acuity, eye, mineralocorticoids, save trial, adverse event, intravitreal injections
Trans. Vis. Sci. Tech.. 2015; 4(2):4. doi: 10.1167/tvst.4.2.4

Articles March 2015

Injectable Chemically Crosslinked Hydrogel for the Controlled Release of Bevacizumab in Vitreous: A 6-Month In Vivo Study

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Yu Yu; Laurence Chi Ming Lau; Amy Cheuk-yin Lo; Ying Chau
TAGS: gel, hydrogel, oryctolagus cuniculus, vitreous body, eye, bevacizumab
Trans. Vis. Sci. Tech.. 2015; 4(2):5. doi: 10.1167/tvst.4.2.5

Includes: Supplemental Content

Articles January 2015

Nanosponge-Mediated Drug Delivery Lowers Intraocular Pressure

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Wendi S. Lambert; Brian J. Carlson; Alice E. van der Ende; Grace Shih; Julia N. Dobish; David J. Calkins; E.a. Harth
TAGS: glaucoma, drug delivery systems, microspheres, eye, intraocular pressure, mice, bimatoprost, travoprost, normal saline, brimonidine, saline solution, intravitreal injections
Trans. Vis. Sci. Tech.. 2015; 4(1):1. doi: 10.1167/tvst.4.1.1

Articles December 2014

Chapter 6 - Restoring Vision to the Blind: Neuroprotection

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The Lasker/IRRF Initiative for Innovation in Vision Science
TAGS: cell death, ciliary neurotrophic factor, neuroprotective agents, vision, neuroprotection, molecule
Trans. Vis. Sci. Tech.. 2014; 3(7):8. doi: 10.1167/tvst.3.7.8

Includes: Supplemental Content

Articles December 2014

Implantable MicroPump for Drug Delivery in Patients with Diabetic Macular Edema

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Mark Humayun; Arturo Santos; Juan Carlos Altamirano; Ramiro Ribeiro; Roberto Gonzalez; Alejandro de la Rosa; Jason Shih; Changling Pang; Fukang Jiang; Philip Calvillo; John Huculak; Jenna Zimmerman; Sean Caffey
TAGS: drug delivery systems, safety, visual acuity, eye, macular edema, diabetic, ranibizumab, implantation procedure
Trans. Vis. Sci. Tech.. 2014; 3(6):5. doi: 10.1167/tvst.3.6.5

Perspective October 2014

Novel Approaches for Retinal Drug and Gene Delivery

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Stephen J. Kim
TAGS: gene therapy, anti-inflammatory agents, non-steroidal, drug delivery systems, genes, hydrogels, animal model, retinal diseases, intravitreal injections
Trans. Vis. Sci. Tech.. 2014; 3(5):7. doi: 10.1167/tvst.3.5.7

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Inhibitory Effects of Angiotensin II Receptor Blockade on Human Tenon Fibroblast Migration and Reactive Oxygen Species Production in Cell Culture

Reviewers

Evaluation of a Sustained-Release Prednisolone Acetate Biodegradable Subconjunctival Implant in a Non-Human Primate Model

Time-Dependent Decline in Multifocal Electroretinogram Requires Faster Recording Procedures in Anesthetized Pigs

Suprachoroidal Corticosteroid Administration: A Novel Route for Local Treatment of Noninfectious Uveitis

Endophthalmitis Prophylaxis Using a Single Drop of Thermoresponsive Controlled-Release Microspheres Loaded with Moxifloxacin in a Rabbit Model

Release of Moxifloxacin from Contact Lenses Using an In Vitro Eye Model: Impact of Artificial Tear Fluid Composition and Mechanical Rubbing

The Accuracy and Reliability of Crowdsource Annotations of Digital Retinal Images

Retinal Arterioles in Hypo-, Normo-, and Hypertensive Subjects Measured Using Adaptive Optics

Selected Antimicrobial Activity of Topical Ophthalmic Anesthetics

A Drug Delivery System for Administration of Anti–TNF-α Antibody

The Effect of Transient Local Anti-inflammatory Treatment on the Survival of Pig Retinal Progenitor Cell Allotransplants

Natural Bioadhesive Biodegradable Nanoparticle-Based Topical Ophthalmic Formulations for Management of Glaucoma

Topical Ocular Drug Delivery to the Back of the Eye by Mucus-Penetrating Particles

One-Year Outcomes of the SAVE Study: S irolimus as a Therapeutic A pproach for U VE itis

Injectable Chemically Crosslinked Hydrogel for the Controlled Release of Bevacizumab in Vitreous: A 6-Month In Vivo Study

Nanosponge-Mediated Drug Delivery Lowers Intraocular Pressure

Chapter 6 - Restoring Vision to the Blind: Neuroprotection

Implantable MicroPump for Drug Delivery in Patients with Diabetic Macular Edema

Novel Approaches for Retinal Drug and Gene Delivery

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