Retina

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Retina December 2024

Longitudinal Changes of Visual Sensitivity With Geographic Atrophy Progression Assessed by Defect-Mapping Microperimetry

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Abera Saeed; Robyn H. Guymer; Xavier Hadoux; Maxime Jannaud; Darvy Dang; Lauren A. B. Hodgson; Emily K. Glover; Erin E. Gee; Peter van Wijngaarden; Zhichao Wu
TAGS: age-related macular degeneration, nonexudative, fundus autofluorescence imaging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):13. https://doi.org/10.1167/iovs.65.14.13

Includes: Supplemental Content

Retina December 2024

Effects of Physical Activity and Inactivity on Microvasculature in Children: The Hong Kong Children Eye Study

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Xiu Juan Zhang; Vincent L. Yuen; Yuzhou Zhang; Ka Wai Kam; Jason Wong; Fang Yao Tang; Alvin Young; Patrick Ip; Li Jia Chen; Tien Y. Wong; Chi Pui Pang; Clement C. Tham; Carol Y. Cheung; Jason C. Yam
TAGS: child, eye, hong kong, lack of exercise, microvascular network, physical activity
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):7. https://doi.org/10.1167/iovs.65.14.7

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics December 2024

Retinal Sensitivity in Comparison to Cone Density in Choroideremia

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Niamh Wynne; Yu You Jiang; Tomas S. Aleman; Jessica I. W. Morgan
TAGS: atrophic condition of skin, choroideremia, retinal cone
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):6. https://doi.org/10.1167/iovs.65.14.6

Retina December 2024

A Novel Grid Strategy for Correlating Focal Macular Anatomic Changes With Focal Changes in Choriocapillaris Perfusion

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Farhan E. Hiya; Yuxuan Cheng; Mengxi Shen; Jianqing Li; Alessandro Berni; Sandy Wenting Zhou; Gissel Herrera; Robert C. O'Brien; Giovanni Gregori; Ruikang K. Wang; Philip J. Rosenfeld
TAGS: chief complaint, drusen, eye, perfusion, reliability, diagnostic imaging, coronary arteriosclerosis, masks, computer assisted diagnosis, computer-aided detection systems
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):5. https://doi.org/10.1167/iovs.65.14.5

Artificial Intelligence December 2024

CNN-Based Device-Agnostic Feature Extraction From ONH OCT Scans

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Sjoerd J. Driessen; Karin A. van Garderen; Danilo Andrade De Jesus; Luisa Sanchez Brea; João Barbosa-Breda; Bart Liefers; Hans G. Lemij; Doreen Nelson-Ayifah; Angelina Ampong; Pieter W. M. Bonnemaijer; Alberta A. H. J. Thiadens; Caroline C. W. Klaver
TAGS: optic disk, biological markers, eye, retinal nerve fiber layer
Trans. Vis. Sci. Tech.. 2024; 13(12):5. https://doi.org/10.1167/tvst.13.12.5

Includes: Supplemental Content

Data Science December 2024

Development of an Open-Source Dataset of Flat-Mounted Images for the Murine Oxygen–Induced Retinopathy Model of Ischemic Retinopathy

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Kyle V. Marra; Jimmy S. Chen; Hailey K. Robles-Holmes; Kristine B. Ly; Joseph Miller; Guoqin Wei; Edith Aguilar; Felicitas Bucher; Yoichi Ideguchi; Fritz Gerald P. Kalaw; Andrew C. Lin; Napoleone Ferrara; J. Peter Campbell; Martin Friedlander; Eric Nudleman
TAGS: datasets, ischemia, mice, oxygen, retinal diseases
Trans. Vis. Sci. Tech.. 2024; 13(12):4. https://doi.org/10.1167/tvst.13.12.4

Includes: Supplemental Content

Retina December 2024

Characterization of the Retinal Circulation of the Mouse

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Fei Shang,; Jesse Schallek
TAGS: mice, retina circulation, vasculature, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):3. https://doi.org/10.1167/iovs.65.14.3

Includes: Multimedia, Supplemental Content

Retina December 2024

The Umbra and the Penumbra: Longitudinal Effects of Geographic Atrophy in AMD on the Outer Choroid by Imaging Analysis and Histopathological Correlation

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Enrico Borrelli; Francesco Cappellani; Jose S. Pulido; Daniel Pauleikhoff; Imran A. Bhutto; D. Scott McLeod; Michele Reibaldi; Malia M. Edwards
TAGS: age-related macular degeneration, nonexudative, choroid, diagnostic imaging, eye, follow-up, histopathology tests, retinal pigment epithelium atrophy, chief complaint
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):2. https://doi.org/10.1167/iovs.65.14.2

Retina December 2024

Design and Characterization of a Novel Intravitreal Dual-Transgene Genetic Medicine for Neovascular Retinopathies

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Melissa A. Calton; Roxanne H. Croze; Christian Burns; Ghezal Beliakoff; Tandis Vazin; Paul Szymanski; Christopher Schmitt; Austin Klein; Meredith Leong; Melissa Quezada; Jenny Holt; Gabe Bolender; Katherine Barglow; Devi Khoday; Thomas Mason; Katherine Delaria; Mohammad Hassanipour; Melissa Kotterman; Arshad M. Khanani; David Schaffer; Peter Francis; David Kirn
TAGS: eye, gene therapy, genetics, retinal diseases, transgenes, spatial vectors, choroidal neovascularization, capsid, primates, disease vectors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):1. https://doi.org/10.1167/iovs.65.14.1

Includes: Supplemental Content

Visual Neuroscience November 2024

Cobalt Toxicity Induces Retinopathy and Optic Neuropathy in Mice

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Basel Obied; Stephen Richard; Alon Zahavi; Hila Kreizman-Shefer; Jacob Bajar; Dror Fixler; Matea Krmpotić; Olga Girshevitz; Nitza Goldenberg-Cohen
TAGS: cobalt, cobalt poisoning, injections, mice, optic nerve, optic nerve disorders, retinal diseases, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):59. https://doi.org/10.1167/iovs.65.13.59

Includes: Supplemental Content

Retina November 2024

Influencing Factors on Pupillary Light Responses as a Biomarker for Local Retinal Function in a Large Normative Cohort

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Ricarda Jendritza; Krunoslav Stingl; Torsten Strasser; Ronja Jung; Felix Tonagel; Paul Richter; Anton Sonntag; Tobias Peters; Helmut Wilhelm; Barbara Wilhelm; Carina Kelbsch
TAGS: biological markers, cardiac progenitor cells, cohort studies, pupil, pupil light reflex, retinal cone, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):3. https://doi.org/10.1167/iovs.65.6.3

Retina November 2024

Comparing IOP-Induced Scleral Deformations in the Myopic and Myopic Glaucoma Spectrums

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Thanadet Chuangsuwanich; Tin A. Tun; Fabian A. Braeu; Rachel S. Chong; Xiaofei Wang; Ching-Lin Ho; Tin Aung; Michaël J. A. Girard; Quan V. Hoang
TAGS: glaucoma, intraocular pressure, macula lutea, sclera, nose, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):54. https://doi.org/10.1167/iovs.65.13.54

Includes: Supplemental Content

Genetics November 2024

Adult Onset Foveomacular Vitelliform Dystrophy Shows Genetic Overlap With Age-Related Macular Degeneration

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Shlomit Jaskoll; Adi Kramer; Sarah Elbaz-Hayoun; Batya Rinsky; Chiara M. Eandi; Michelle Grunin; Yahel Shwartz; Liran Tiosano; Iris M. Heid; Thomas Winkler; Itay Chowers
TAGS: adult, age-related macular degeneration, genetics, vitelliform dystrophy, complement system proteins, complement activation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):53. https://doi.org/10.1167/iovs.65.13.53

Includes: Supplemental Content

Retina November 2024

Subretinal Amniotic Membrane Transplantation in a Porcine Model of Retinal Hole

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Madeline E. Olufsen; Jens Hannibal; Nina B. Sørensen; Anders T. Christiansen; Ulrik C. Christensen; Grazia Pertile; David H. Steel; Steffen Heegaard; Jens F. Kiilgaard
TAGS: amnion, retinal perforations, suidae, transplantation, follow-up, surgical procedures, operative
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):52. https://doi.org/10.1167/iovs.65.13.52

Includes: Supplemental Content

Retina November 2024

Diabetes Renders Photoreceptors Susceptible to Retinal Ischemia-Reperfusion Injury

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David A. Antonetti; Cheng-Mao Lin; Sumathi Shanmugam; Heather Hager; Manjing Cao; Xuwen Liu; Alyssa Dreffs; Adam Habash; Steven F. Abcouwer
TAGS: diabetes mellitus, wounds and injuries, mice, retina, photoreceptors, reperfusion injury, streptozocin
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):46. https://doi.org/10.1167/iovs.65.13.46

Includes: Supplemental Content

Low Vision Rehabilitation November 2024

Aligning Visual Prosthetic Development With Implantee Needs

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Lucas Nadolskis; Lily M. Turkstra; Ebenezer Larnyo; Michael Beyeler
TAGS: implants, research personnel, visual prosthesis
Trans. Vis. Sci. Tech.. 2024; 13(11):28. https://doi.org/10.1167/tvst.13.11.28

Includes: Supplemental Content

Retina November 2024

Automated Detection of Drusenoid Pigment Epithelial Detachments From Spectral-Domain Optical Coherence Tomography in Patients With AMD

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Souvick Mukherjee; Cameron Duic; Tharindu De Silva; Tiarnan D. L. Keenan; Alisa T. Thavikulwat; Emily Y. Chew; Catherine Cukras
TAGS: drusen, retinal pigment epithelial detachment, spectral domain-optical coherence tomography, reading (activity), eye
Trans. Vis. Sci. Tech.. 2024; 13(11):25. https://doi.org/10.1167/tvst.13.11.25

Includes: Supplemental Content

Retina November 2024

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

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Nicole A. Muench; Heather M. Schmitt; Cassandra L. Schlamp; An-Jey A. Su; Kia Washington; Robert W. Nickells
TAGS: cryopreservation, eye, mice
Trans. Vis. Sci. Tech.. 2024; 13(11):24. https://doi.org/10.1167/tvst.13.11.24

Includes: Supplemental Content

Retina November 2024

Three-Dimensional Choroidal Vessels Assessment in Age-Related Macular Degeneration

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Elham Sadeghi; Nicola Valsecchi; Mohammed Nasar Ibrahim; Katherine Du; Elli Davis; Sandeep Chandra Bollepalli; Kiran Kumar Vupparaboina; Jose Alain Sahel; Jay Chhablani
TAGS: age-related macular degeneration, cardiovascular imaging, cortical blindness, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):39. https://doi.org/10.1167/iovs.65.13.39

Retina November 2024

Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa

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Akishi Onishi; Yuji Tsunekawa; Michiko Mandai; Aiko Ishimaru; Yoko Ohigashi; Junki Sho; Kazushi Yasuda; Keiichiro Suzuki; Juan Carlos Izpisua Belmonte; Fumio Matsuzaki; Masayo Takahashi
TAGS: genes, genome editing, mice, retinitis pigmentosa, rhodopsin, rod photoreceptors, donors, plasmids, electroporation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):38. https://doi.org/10.1167/iovs.65.13.38

Includes: Supplemental Content

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Longitudinal Changes of Visual Sensitivity With Geographic Atrophy Progression Assessed by Defect-Mapping Microperimetry

Effects of Physical Activity and Inactivity on Microvasculature in Children: The Hong Kong Children Eye Study

Retinal Sensitivity in Comparison to Cone Density in Choroideremia

A Novel Grid Strategy for Correlating Focal Macular Anatomic Changes With Focal Changes in Choriocapillaris Perfusion

CNN-Based Device-Agnostic Feature Extraction From ONH OCT Scans

Development of an Open-Source Dataset of Flat-Mounted Images for the Murine Oxygen–Induced Retinopathy Model of Ischemic Retinopathy

Characterization of the Retinal Circulation of the Mouse

The Umbra and the Penumbra: Longitudinal Effects of Geographic Atrophy in AMD on the Outer Choroid by Imaging Analysis and Histopathological Correlation

Design and Characterization of a Novel Intravitreal Dual-Transgene Genetic Medicine for Neovascular Retinopathies

Cobalt Toxicity Induces Retinopathy and Optic Neuropathy in Mice

Influencing Factors on Pupillary Light Responses as a Biomarker for Local Retinal Function in a Large Normative Cohort

Comparing IOP-Induced Scleral Deformations in the Myopic and Myopic Glaucoma Spectrums

Adult Onset Foveomacular Vitelliform Dystrophy Shows Genetic Overlap With Age-Related Macular Degeneration

Subretinal Amniotic Membrane Transplantation in a Porcine Model of Retinal Hole

Diabetes Renders Photoreceptors Susceptible to Retinal Ischemia-Reperfusion Injury

Aligning Visual Prosthetic Development With Implantee Needs

Automated Detection of Drusenoid Pigment Epithelial Detachments From Spectral-Domain Optical Coherence Tomography in Patients With AMD

Preservation of Murine Whole Eyes With Supplemented UW Cold Storage Solution: Anatomical Considerations

Three-Dimensional Choroidal Vessels Assessment in Age-Related Macular Degeneration

Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa

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