Retina

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Retina April 2025

Instrumenting Carotid Sonography Biomarkers and Polygenic Risk Score As a Novel Screening Approach for Retinal Detachment

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Kao-Jung Chang; Ching-Yun Wang; Hsin-Yu Wu; Pei-Yu Weng; Chia-Hsin Lu; Wei Chiu; Wei-Chieh Fang; Chong-En Kao; Cheng-Yi Li; Yi-Ting Chung; Yu-Chun Chen; Ai-Ru Hsieh; Shih-Hwa Chiou; Chih-Chien Hsu; Tai-Chi Lin; Shih-Jen Chen; De-Kuang Hwang
TAGS: biological markers, polygenic risk score, retinal detachment, screening, ultrasonography, hypertension
Trans. Vis. Sci. Tech.. 2025; 14(4):16. https://doi.org/10.1167/tvst.14.4.16

Includes: Supplemental Content

Letters to the Editor April 2025

Comments on Xie et al.’s Study on Artificial Intelligence–Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy

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James Lin; Ting-Wan Kao
TAGS: artificial intelligence, biological markers, diabetic nephropathy, perfusion, screening
Trans. Vis. Sci. Tech.. 2025; 14(4):11. https://doi.org/10.1167/tvst.14.4.11

Letters to the Editor April 2025

The Future of Retinitis Pigmentosa Research: Unlocking the Potential of Branched-Chain Amino Acid Therapy

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Qinling Jiang; Lin Mou
TAGS: amino acids, branched-chain, retinitis pigmentosa
Trans. Vis. Sci. Tech.. 2025; 14(4):10. https://doi.org/10.1167/tvst.14.4.10

Artificial Intelligence March 2025

Multimodal Artificial Intelligence Models Predicting Glaucoma Progression Using Electronic Health Records and Retinal Nerve Fiber Layer Scans

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Abigail Koornwinder; Youchen Zhang; Rohith Ravindranath; Robert T. Chang; Isaac A. Bernstein; Sophia Y. Wang
TAGS: artificial intelligence, electronic medical records, glaucoma, retinal nerve fiber layer, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2025; 14(3):27. https://doi.org/10.1167/tvst.14.3.27

Includes: Supplemental Content

Artificial Intelligence March 2025

Anomaly Detection in Retinal OCT Images With Deep Learning-Based Knowledge Distillation

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Guilherme Aresta; Teresa Araújo; Ursula Schmidt-Erfurth; Hrvoje Bogunović
TAGS: datasets, distillation, learning, volume, severity of illness, maps, screening
Trans. Vis. Sci. Tech.. 2025; 14(3):26. https://doi.org/10.1167/tvst.14.3.26

Retina March 2025

Addressing Multiplicity in Retinal Sensitivity Analysis: An Alternative Approach to Assessing Gene Therapy Efficacy in Inherited Retinal Diseases

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Antonio Yaghy; David G. Birch; Yunchan Hwang; Edmund Luo; JungAh Jung; Darin Curtiss; Nadia K. Waheed
TAGS: gene therapy, retinal diseases, sensitivity analysis, treatment effect
Trans. Vis. Sci. Tech.. 2025; 14(3):25. https://doi.org/10.1167/tvst.14.3.25

Retina March 2025

Carboxyamidotriazole Complexed to PLGA Is Safe, Effective, and Durable in Models of Neovascular Retinal Disease

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Sergio Li Calzi; Ayaka Fujihashi; Dibyendu Chakraborty; Yvonne Adu-Rutledge; Ram Prasad; Edgar L. V. Ready; Sarbodeep Paul; Srikanth Kakumanu; Xiaoping Qi; Michael E. Boulton; Alan J. Franklin; Bob H. Katz; Maria B. Grant
TAGS: aflibercept, choroidal neovascularization, implants, lasers, oryctolagus cuniculus, polymers, retinal diseases, intravitreal injections, mice, injections
Trans. Vis. Sci. Tech.. 2025; 14(3):21. https://doi.org/10.1167/tvst.14.3.21

Retina March 2025

Quantifying the Progression of Stargardt Disease in Double-Null ABCA4 Carriers Using Fundus Autofluorescence Imaging

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Ivana Mihalek; Hanna De Bruyn; Tomislav Glavan; Annie M. Lancos; Caitlin M. Ciolfi; Katarzyna Malendowicz; Sigrid Aslaksen; Laurie L. Molday; Robert S. Molday; Anne B. Fulton
TAGS: abca4 gene, fovea centralis, fundus autofluorescence imaging, pixel, stargardt's disease, artifacts, eye
Trans. Vis. Sci. Tech.. 2025; 14(3):16. https://doi.org/10.1167/tvst.14.3.16

Includes: Supplemental Content

Retina March 2025

The Combination of Retinal Neurovascular Unit Changes With Carotid Artery Stenosis Enhances the Prediction of Ischemic Stroke

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Zhifan Chen; Shuoxin Liao; Guangzhong Chen; Changmao Li; Chunling Liu; Junbin Liu; Guangyu Wu; Zheng Lyu; Mengya Liu; Xiyu Wu; Guixian Ma; Qianli Meng
TAGS: carotid stenosis, ischemic stroke
Trans. Vis. Sci. Tech.. 2025; 14(3):14. https://doi.org/10.1167/tvst.14.3.14

Includes: Supplemental Content

Public Health March 2025

Visual Deficits in Type 2 Diabetes Mellitus Without Retinopathy: From Retinal Structure to Higher-Level Visual Functions

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Sha Luo; Lin Xia; Yue Wang; Yong Tang; Jiong Dong; Rong Liu; Lixia Feng
TAGS: diabetes mellitus, diabetes mellitus, type 2, retina, retinal diseases, vision, vision disorders
Trans. Vis. Sci. Tech.. 2025; 14(3):10. https://doi.org/10.1167/tvst.14.3.10

Includes: Supplemental Content

Review March 2025

Advances in OCT Angiography

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Tristan T. Hormel; David Huang; Yali Jia
TAGS: angiogram, artifacts, diagnostic imaging, deep learning, fluid flow, body tissue
Trans. Vis. Sci. Tech.. 2025; 14(3):6. https://doi.org/10.1167/tvst.14.3.6

Retina March 2025

Application of 3D MRI and SS-OCT/OCTA in Assessment of Posterior Scleral Contraction for Myopic Traction Maculopathy

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Danyang Yu; Di Wu; Haoru Li; Hua Rong; Qing He; Xia Zhang; He Xu; Mengdi Chai; Yifan Zhou; Ruihua Wei
TAGS: 3d mri, myopic foveoschisis, sclera, surgical procedures, operative, preoperative care, postoperative care, retinoschisis
Trans. Vis. Sci. Tech.. 2025; 14(3):5. https://doi.org/10.1167/tvst.14.3.5

Artificial Intelligence March 2025

An Intelligent Grading Model for Myopic Maculopathy Based on Long-Tailed Learning

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Bo Zheng; Chen Wang; Maotao Zhang; Shaojun Zhu; Maonian Wu; Tao Wu; Weihua Yang; Lu Chen
TAGS: learning, macular disorders, fundus photography, color, datasets
Trans. Vis. Sci. Tech.. 2025; 14(3):4. https://doi.org/10.1167/tvst.14.3.4

Includes: Supplemental Content

Retina March 2025

Photoreceptor Outer Segment Reflectivity With Ultrahigh-Resolution Visible-Light Optical Coherence Tomography in Systemic Hydroxychloroquine Use

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Anupam K. Garg; Jingyu Wang; Bailee Alonzo; Ji Yi; Amir H. Kashani
TAGS: hydroxychloroquine, optical coherence tomography, photoreceptors, vaccine information sheets, visible light, diagnostic imaging, toxic effect
Trans. Vis. Sci. Tech.. 2025; 14(3):2. https://doi.org/10.1167/tvst.14.3.2

Includes: Supplemental Content

Retina February 2025

Evaluating Blood Flow Speed in Retinal Microaneurysms Secondary to Diabetic Retinopathy Using Variable Interscan Time Analysis OCTA

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Hiroyuki Takahashi; Yunchan Hwang; Jungeun Won; Muhammad Usman Jamil; Antonio Yaghy; Michelle C. Liang; Caroline R. Baumal; Andre J. Witkin; Kyoko Ohno-Matsui; Jay S. Duker; James G. Fujimoto; Nadia K. Waheed
TAGS: diabetic retinal microaneurysm, diabetic retinopathy, fluid flow, macrophage activation syndrome, meconium aspiration syndrome, retinal microaneurysm, vascular flow, blood capillaries
Trans. Vis. Sci. Tech.. 2025; 14(2):27. https://doi.org/10.1167/tvst.14.2.27

Artificial Intelligence February 2025

Automated Detection of Retinal Detachment Using Deep Learning-Based Segmentation on Ocular Ultrasonography Images

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Onur Caki; Umit Yasar Guleser; Dilek Ozkan; Mehmet Harmanli; Selahattin Cansiz; Cem Kesim; Rustu Emre Akcan; Ivan Merdzo; Murat Hasanreisoglu; Cigdem Gunduz-Demir
TAGS: learning, retinal detachment, training, ultrasonography, retina, choroid
Trans. Vis. Sci. Tech.. 2025; 14(2):26. https://doi.org/10.1167/tvst.14.2.26

Retina February 2025

OCT Angiography of Type 1 Macular Neovascularization in AMD: A Morphometric Evaluation

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Maria Cristina Savastano; Claudia Fossataro; Matteo Mario Carlà; Valentina Cestrone; Ilaria Biagini; Clara Rizzo; Raphael Kilian; Sandrine A. Zweifel; Daniel R. Muth; Francesco Faraldi; Stanislao Rizzo; David Sarraf
TAGS: macular neovascularization, angiogram, biological markers
Trans. Vis. Sci. Tech.. 2025; 14(2):23. https://doi.org/10.1167/tvst.14.2.23

Retina February 2025

Idiopathic Macular Hole Area to Foveal Avascular Zone Ratio and Its Effects on Visual Acuity Before and After Surgery

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Junji Kanno; Takuhei Shoji; Hirokazu Ishii; Hisashi Ibuki; Yuji Yoshikawa; Takanori Sasaki; Kei Shinoda
TAGS: macular holes, preoperative care, surgical procedures, operative, visual acuity, regression analysis, postoperative care, face
Trans. Vis. Sci. Tech.. 2025; 14(2):22. https://doi.org/10.1167/tvst.14.2.22

Includes: Multimedia, Supplemental Content

Retina February 2025

Association Between Hormone Levels and Retinopathy in Patients With Type 2 Diabetes: A Cross-Sectional Study

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Yu Meng; Xueli Yang; Yuxin Fan; Ming Liu; Fengqi Zhou; Qihua Wang; Yuezhu Lu; Yun Zhu; Hua Yan
TAGS: diabetes mellitus, type 2, gonadal hormones, hormones, retinal diseases, testosterone
Trans. Vis. Sci. Tech.. 2025; 14(2):17. https://doi.org/10.1167/tvst.14.2.17

Includes: Supplemental Content

Artificial Intelligence February 2025

Deep Learning Approaches to Predict Geographic Atrophy Progression Using Three-Dimensional OCT Imaging

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Kenta Yoshida; Neha Anegondi; Adam Pely; Miao Zhang; Frederic Debraine; Karthik Ramesh; Verena Steffen; Simon S. Gao; Catherine Cukras; Christina Rabe; Daniela Ferrara; Richard F. Spaide; SriniVas R. Sadda; Frank G. Holz; Qi Yang
TAGS: age-related macular degeneration, nonexudative, datasets, deep learning, diagnostic imaging, growth rate
Trans. Vis. Sci. Tech.. 2025; 14(2):11. https://doi.org/10.1167/tvst.14.2.11

Includes: Supplemental Content

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Instrumenting Carotid Sonography Biomarkers and Polygenic Risk Score As a Novel Screening Approach for Retinal Detachment

Comments on Xie et al.’s Study on Artificial Intelligence–Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy

The Future of Retinitis Pigmentosa Research: Unlocking the Potential of Branched-Chain Amino Acid Therapy

Multimodal Artificial Intelligence Models Predicting Glaucoma Progression Using Electronic Health Records and Retinal Nerve Fiber Layer Scans

Anomaly Detection in Retinal OCT Images With Deep Learning-Based Knowledge Distillation

Addressing Multiplicity in Retinal Sensitivity Analysis: An Alternative Approach to Assessing Gene Therapy Efficacy in Inherited Retinal Diseases

Carboxyamidotriazole Complexed to PLGA Is Safe, Effective, and Durable in Models of Neovascular Retinal Disease

Quantifying the Progression of Stargardt Disease in Double-Null ABCA4 Carriers Using Fundus Autofluorescence Imaging

The Combination of Retinal Neurovascular Unit Changes With Carotid Artery Stenosis Enhances the Prediction of Ischemic Stroke

Visual Deficits in Type 2 Diabetes Mellitus Without Retinopathy: From Retinal Structure to Higher-Level Visual Functions

Advances in OCT Angiography

Application of 3D MRI and SS-OCT/OCTA in Assessment of Posterior Scleral Contraction for Myopic Traction Maculopathy

An Intelligent Grading Model for Myopic Maculopathy Based on Long-Tailed Learning

Photoreceptor Outer Segment Reflectivity With Ultrahigh-Resolution Visible-Light Optical Coherence Tomography in Systemic Hydroxychloroquine Use

Evaluating Blood Flow Speed in Retinal Microaneurysms Secondary to Diabetic Retinopathy Using Variable Interscan Time Analysis OCTA

Automated Detection of Retinal Detachment Using Deep Learning-Based Segmentation on Ocular Ultrasonography Images

OCT Angiography of Type 1 Macular Neovascularization in AMD: A Morphometric Evaluation

Idiopathic Macular Hole Area to Foveal Avascular Zone Ratio and Its Effects on Visual Acuity Before and After Surgery

Association Between Hormone Levels and Retinopathy in Patients With Type 2 Diabetes: A Cross-Sectional Study

Deep Learning Approaches to Predict Geographic Atrophy Progression Using Three-Dimensional OCT Imaging

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