Translational Research

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Articles May 2021

Feasibility Study of a Multimodal, Cloud-Based, Diabetic Retinal Screening Program in a Workplace Environment

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Jeffrey R. Willis; Ferhina S. Ali; Braelyn Argente; Amitha Domalpally; Jacqueline Gannon; Simon S. Gao; Shagun Grover; Purti Kanodia; Sparkle Russell-Puleri; Diana Sun; Cory Thrasher; Costas Tsougarakis; J. Jill Hopkins
TAGS: diabetes mellitus, feasibility studies, retinal screening, workplace, vision, self-report, transfer technique
Trans. Vis. Sci. Tech.. 2021; 10(6):20. doi: https://doi.org/10.1167/tvst.10.6.20

Includes: Supplemental Content

Articles May 2021

Automatic Anterior Chamber Angle Classification Using Deep Learning System and Anterior Segment Optical Coherence Tomography Images

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Wanyue Li; Qian Chen; Chunhui Jiang; Guohua Shi; Guohua Deng; Xinghuai Sun
TAGS: angle's classification, anterior chamber of eye, deep learning, optical coherence tomography, learning, datasets, transfer technique, ultrasound biomicroscopy, judgment
Trans. Vis. Sci. Tech.. 2021; 10(6):19. doi: https://doi.org/10.1167/tvst.10.6.19

Includes: Supplemental Content

Articles May 2021

Imaging Biomarkers of 1-Year Activity in Type 1 Macular Neovascularization

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Eliana Costanzo; Mariacristina Parravano; Daniela Giannini; Enrico Borrelli; Riccardo Sacconi; Giuseppe Querques
TAGS: biological markers, diagnostic imaging, neovascularization, pathologic, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2021; 10(6):18. doi: https://doi.org/10.1167/tvst.10.6.18

Articles May 2021

Validating Ellipsoid Zone Area Measurement With Multimodal Imaging in Choroideremia

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Yi Zhai; Sarah Oke; Ian M. MacDonald
TAGS: choroideremia, eye, face, multimodal imaging, photoreceptors, meridians
Trans. Vis. Sci. Tech.. 2021; 10(6):17. doi: https://doi.org/10.1167/tvst.10.6.17

Includes: Supplemental Content

Articles May 2021

Retinal Differential Light Sensitivity Variation Across the Macula in Healthy Subjects: Importance of Cone Separation and Loci Eccentricity

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Danuta M. Sampson; Danial Roshandel; Avenell L. Chew; Yufei Wang; Paul G. Stevenson; Matthew N. Cooper; Elaine Ong; Lawrence Wong; Jonathan La; David Alonso-Caneiro; Enid Chelva; Jane C. Khan; David D. Sampson; Fred K. Chen
TAGS: macula lutea, photophobia, retinal cone, photon correlation spectroscopy
Trans. Vis. Sci. Tech.. 2021; 10(6):16. doi: https://doi.org/10.1167/tvst.10.6.16

Includes: Supplemental Content

Articles May 2021

Longitudinal Evaluation of Hyper-Reflective Foci in the Retina Following Subretinal Delivery of Adeno-Associated Virus in Non-Human Primates

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Eduardo Rodríguez-Bocanegra; Fabian Wozar; Immanuel P. Seitz; Felix F. L. Reichel; Alex Ochakovski; Kirsten Bucher; Barbara Wilhelm; K. Ulrich Bartz-Schmidt; Tobias Peters; M. Dominik Fischer; for the RD-CURE Consortium
TAGS: adeno-associated virus, eye, gene therapy, injections, primates, retina, spectral domain-optical coherence tomography, surgical procedures, operative, microglia
Trans. Vis. Sci. Tech.. 2021; 10(6):15. doi: https://doi.org/10.1167/tvst.10.6.15

Includes: Supplemental Content

Review May 2021

Risk Stratification and Clinical Utility of Polygenic Risk Scores in Ophthalmology

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Ayub Qassim; Emmanuelle Souzeau; Georgie Hollitt; Mark M. Hassall; Owen M. Siggs; Jamie E. Craig
TAGS: genetics, genome-wide association study, myopia, open-angle glaucoma, ophthalmology, stratification, cohort studies, glaucoma, single nucleotide polymorphism, screening
Trans. Vis. Sci. Tech.. 2021; 10(6):14. doi: https://doi.org/10.1167/tvst.10.6.14

Articles May 2021

Anterior Chamber Measurements in Healthy Children: A Cross-Sectional Study Using Optical Coherence Tomography

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Budor S. A. Edawaji; Irene Gottlob; Frank A. Proudlock
TAGS: anterior chamber of eye, optical coherence tomography, well child, nose
Trans. Vis. Sci. Tech.. 2021; 10(6):13. doi: https://doi.org/10.1167/tvst.10.6.13

Includes: Supplemental Content

Articles May 2021

Calibration of the Activity Inventory Item Bank: A Patient-Reported Outcome Measurement Instrument for Low Vision Rehabilitation

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Micaela Gobeille; Chris Bradley; Judith E. Goldstein; Robert Massof
TAGS: blind rehabilitation therapy, calibration, patient self-report, mobility, reading (activity), visual impairment
Trans. Vis. Sci. Tech.. 2021; 10(6):12. doi: https://doi.org/10.1167/tvst.10.6.12

Includes: Supplemental Content

Articles May 2021

A Baseline Score to Predict Response to Ranibizumab Treatment in Neovascular Age-Related Macular Degeneration

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Cheikh Diack; Dietmar Schwab; Valerie Cosson; Vincent Buchheit; Norman Mazer; Nicolas Frey
TAGS: ranibizumab, exudative age-related macular degeneration
Trans. Vis. Sci. Tech.. 2021; 10(6):11. doi: https://doi.org/10.1167/tvst.10.6.11

Includes: Supplemental Content

Articles May 2021

Focal Loss Analysis of Nerve Fiber Layer Reflectance for Glaucoma Diagnosis

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Ou Tan; Liang Liu; Qisheng You; Jie Wang; Aiyin Chen; Eliesa Ing; John C. Morrison; Yali Jia; David Huang
TAGS: glaucoma, nerve fibers, eye
Trans. Vis. Sci. Tech.. 2021; 10(6):9. doi: https://doi.org/10.1167/tvst.10.6.9

Includes: Supplemental Content

Articles May 2021

Lactobacillus sakei Pro-Bio65 Reduces TNF-α Expression and Upregulates GSH Content and Antioxidant Enzymatic Activities in Human Conjunctival Cells

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Roberto Iorio; Sabrina Petricca; Carla Luzi; Pierangelo Bellio; Loredana Cristiano; Claudio Festuccia; Gianfranco Amicosante; Giuseppe Celenza
TAGS: antioxidants, conjunctiva, lactobacillus sakei, tumor necrosis factors, mitochondria
Trans. Vis. Sci. Tech.. 2021; 10(6):8. doi: https://doi.org/10.1167/tvst.10.6.8

Articles May 2021

Optogenetic Modulation of Intraocular Pressure in a Glucocorticoid-Induced Ocular Hypertension Mouse Model

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Tia J. Kowal; Philipp P. Prosseda; Ke Ning; Biao Wang; Jorge Alvarado; Brent E. Sendayen; Sayena Jabbehdari; W. Daniel Stamer; Yang Hu; Yang Sun
TAGS: dexamethasone, glucocorticoids, intraocular pressure, mice, ocular hypertension, oculocerebrorenal syndrome, optogenetics, eye
Trans. Vis. Sci. Tech.. 2021; 10(6):10. doi: https://doi.org/10.1167/tvst.10.6.10

Articles May 2021

Advanced Retinal Imaging and Ocular Parameters of the Rhesus Macaque Eye

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Kira H. Lin; Tu Tran; Soohyun Kim; Sangwan Park; J. Timothy Stout; Rui Chen; Jeffrey Rogers; Glenn Yiu; Sara Thomasy; Ala Moshiri
TAGS: eye, macaca mulatta, diagnostic imaging of retina, electroretinography
Trans. Vis. Sci. Tech.. 2021; 10(6):7. doi: https://doi.org/10.1167/tvst.10.6.7

Articles May 2021

Longitudinal Study of Retinal Structure, Vascular, and Neuronal Function in Patients With Relapsing-Remitting Multiple Sclerosis: 1-Year Follow-Up

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Qi Chen; Hong Jiang; Silvia Delgado; Jeffrey Hernandez; Diego Eduardo Alba; Giovanni Gregori; Kottil W. Rammohan; Vittorio Porciatti; Jianhua Wang
TAGS: follow-up, longitudinal studies, multiple sclerosis, relapsing-remitting, retina, eye, medical history
Trans. Vis. Sci. Tech.. 2021; 10(6):6. doi: https://doi.org/10.1167/tvst.10.6.6

Articles May 2021

Development of a Web-Based Ensemble Machine Learning Application to Select the Optimal Size of Posterior Chamber Phakic Intraocular Lens

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Eun Min Kang; Ik Hee Ryu; Geunyoung Lee; Jin Kuk Kim; In Sik Lee; Ga Hee Jeon; Hojin Song; Kazutaka Kamiya; Tae Keun Yoo
TAGS: datasets, internet, intraocular lens implant device, machine learning, postoperative care, lens (device)
Trans. Vis. Sci. Tech.. 2021; 10(6):5. doi: https://doi.org/10.1167/tvst.10.6.5

Includes: Supplemental Content

Articles May 2021

Relating Retinal Vascular Oxygen Saturation and Microvasculature Morphology at Progressive Stages of Diabetic Retinopathy

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Selin L. Auvazian; Jennifer Cano; Sophie Leahy; Preny Karamian; Amir Kashani; Andrew Moshfeghi; Hossein Ameri; Norman P. Blair; Mahnaz Shahidi
TAGS: diabetic retinopathy, language morphology, microvascular network, morphology, oxygen saturation measurement, nonproliferative diabetic retinopathy
Trans. Vis. Sci. Tech.. 2021; 10(6):4. doi: https://doi.org/10.1167/tvst.10.6.4

Articles May 2021

Comprehensive Proteomic Profiling of Aqueous Humor Proteins in Proliferative Diabetic Retinopathy

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Hu Xiao; Wen Xin; Li Mei Sun; Song Shan Li; Ting Zhang; Xiao Yan Ding
TAGS: hypertension, proliferative diabetic retinopathy, proteins, aqueous humor
Trans. Vis. Sci. Tech.. 2021; 10(6):3. doi: https://doi.org/10.1167/tvst.10.6.3

Articles May 2021

Model Structure Uncertainty in the Characterization and Growth of Geographic Atrophy

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Janan Arslan; Kurt K. Benke; Gihan Samarasinghe; Arcot Sowmya; Robyn H. Guymer; Paul N. Baird
TAGS: atrophy, regression analysis, eye, surgical instruments
Trans. Vis. Sci. Tech.. 2021; 10(6):2. doi: https://doi.org/10.1167/tvst.10.6.2

Includes: Supplemental Content

Articles May 2021

Automatic Recording of the Target Location During Smooth Pursuit Eye Movement Testing Using Video-Oculography and Deep Learning-Based Object Detection

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Masakazu Hirota; Takao Hayashi; Emiko Watanabe; Yuji Inoue; Atsushi Mizota
TAGS: eye, eye movement, learning, pursuit, smooth, strabismus
Trans. Vis. Sci. Tech.. 2021; 10(6):1. doi: https://doi.org/10.1167/tvst.10.6.1

Includes: Multimedia, Supplemental Content

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Feasibility Study of a Multimodal, Cloud-Based, Diabetic Retinal Screening Program in a Workplace Environment

Automatic Anterior Chamber Angle Classification Using Deep Learning System and Anterior Segment Optical Coherence Tomography Images

Imaging Biomarkers of 1-Year Activity in Type 1 Macular Neovascularization

Validating Ellipsoid Zone Area Measurement With Multimodal Imaging in Choroideremia

Retinal Differential Light Sensitivity Variation Across the Macula in Healthy Subjects: Importance of Cone Separation and Loci Eccentricity

Longitudinal Evaluation of Hyper-Reflective Foci in the Retina Following Subretinal Delivery of Adeno-Associated Virus in Non-Human Primates

Risk Stratification and Clinical Utility of Polygenic Risk Scores in Ophthalmology

Anterior Chamber Measurements in Healthy Children: A Cross-Sectional Study Using Optical Coherence Tomography

Calibration of the Activity Inventory Item Bank: A Patient-Reported Outcome Measurement Instrument for Low Vision Rehabilitation

A Baseline Score to Predict Response to Ranibizumab Treatment in Neovascular Age-Related Macular Degeneration

Focal Loss Analysis of Nerve Fiber Layer Reflectance for Glaucoma Diagnosis

Lactobacillus sakei Pro-Bio65 Reduces TNF-α Expression and Upregulates GSH Content and Antioxidant Enzymatic Activities in Human Conjunctival Cells

Optogenetic Modulation of Intraocular Pressure in a Glucocorticoid-Induced Ocular Hypertension Mouse Model

Advanced Retinal Imaging and Ocular Parameters of the Rhesus Macaque Eye

Longitudinal Study of Retinal Structure, Vascular, and Neuronal Function in Patients With Relapsing-Remitting Multiple Sclerosis: 1-Year Follow-Up

Development of a Web-Based Ensemble Machine Learning Application to Select the Optimal Size of Posterior Chamber Phakic Intraocular Lens

Relating Retinal Vascular Oxygen Saturation and Microvasculature Morphology at Progressive Stages of Diabetic Retinopathy

Comprehensive Proteomic Profiling of Aqueous Humor Proteins in Proliferative Diabetic Retinopathy

Model Structure Uncertainty in the Characterization and Growth of Geographic Atrophy

Automatic Recording of the Target Location During Smooth Pursuit Eye Movement Testing Using Video-Oculography and Deep Learning-Based Object Detection

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