Visual Neuroscience

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Articles October 2020

Laser Capture Microdissection-Based RNA Microsequencing Reveals Optic Nerve Crush-Related Early mRNA Alterations in Retinal Ganglion Cell Layer

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Dongyan Pan; Mengqiao Xu; Xin Chang; Mao Xia; Yibin Fang; Yinghua Fu; Wei Shen; Yue Wang; Xiaodong Sun
TAGS: lasers, microdissection, optic nerve, rna, rna, messenger, retinal ganglion cells, genes, sequence analysis, rna
Trans. Vis. Sci. Tech.. 2020; 9(11):30. doi: https://doi.org/10.1167/tvst.9.11.30

Includes: Supplemental Content

Review October 2020

Probing ON and OFF Retinal Pathways in Glaucoma Using Electroretinography

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Alan W. Kong; Luca Della Santina; Yvonne Ou
TAGS: electroretinography, erg protein, human, glaucoma
Trans. Vis. Sci. Tech.. 2020; 9(11):14. doi: https://doi.org/10.1167/tvst.9.11.14

Articles October 2020

The RUSH2A Study: Best-Corrected Visual Acuity, Full-Field Electroretinography Amplitudes, and Full-Field Stimulus Thresholds at Baseline

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David G. Birch; Peiyao Cheng; Jacque L. Duncan; Allison R. Ayala; Maureen G. Maguire; Isabelle Audo; Janet K. Cheetham; Todd A. Durham; Abigail T. Fahim; Frederick L. Ferris, III; Elise Heon; Rachel M. Huckfeldt; Alessandro Iannaccone; Naheed W. Khan; Eleonora M. Lad; Michel Michaelides; Mark E. Pennesi; Katarina Stingl; Ajoy Vincent; Christina Y. Weng; for the Foundation Fighting Blindness Consortium Investigator Group
TAGS: electroretinography, visual acuity
Trans. Vis. Sci. Tech.. 2020; 9(11):9. doi: https://doi.org/10.1167/tvst.9.11.9

Includes: Supplemental Content

Articles October 2020

Anatomical Location of the Raphe and Extended Raphe in the Human Retina: Implications for Assessment of the Optic Nerve with OCT

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Nomdo M. Jansonius; Ulrich Schiefer
TAGS: fovea centralis, optic disk, optic nerve, retina, datasets, eye
Trans. Vis. Sci. Tech.. 2020; 9(11):3. doi: https://doi.org/10.1167/tvst.9.11.3

Includes: Supplemental Content

Articles October 2020

Mitochondrial Transfer of the Mutant Human ND6T14484C Gene Causes Visual Loss and Optic Neuropathy

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Hong Yu; David W. Sant; Gaofeng Wang; John Guy
TAGS: blindness, genes, mice, mitochondrial donation, optic atrophy, hereditary, leber, optic nerve disorders, carrying, injections
Trans. Vis. Sci. Tech.. 2020; 9(11):1. doi: https://doi.org/10.1167/tvst.9.11.1

Includes: Supplemental Content

Articles September 2020

Artifact Rates for 2D Retinal Nerve Fiber Layer Thickness Versus 3D Neuroretinal Rim Thickness Using Spectral-Domain Optical Coherence Tomography

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Elli A. Park; Edem Tsikata; Jenny Jyoung Lee; Eric Shieh; Boy Braaf; Benjamin J. Vakoc; Brett E. Bouma; Johannes F. de Boer; Teresa C. Chen
TAGS: artifacts, glaucoma, retinal nerve fiber layer, spectral domain-optical coherence tomography, neuroretinal rim
Trans. Vis. Sci. Tech.. 2020; 9(10):10. doi: https://doi.org/10.1167/tvst.9.10.10

Includes: Supplemental Content

Articles September 2020

Dynamics of Contrast Decrement and Increment Responses in Human Visual Cortex

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Anthony M. Norcia; Alexandra Yakovleva; Bethany Hung; Jeffrey L. Goldberg
TAGS: luminance, photic stimulation, visual cortex, visual fields, waveforms, polarity, harmonics
Trans. Vis. Sci. Tech.. 2020; 9(10):6. doi: https://doi.org/10.1167/tvst.9.10.6

Articles August 2020

Electrophysiological and Pupillometric Abnormalities in PROM1 Cone–Rod Dystrophy

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Jason C. Park; Frederick T. Collison; Gerald A. Fishman; J. Jason McAnany
TAGS: electroretinography, passive leg raising, progressive cone-rod dystrophy, retinitis pigmentosa, luminance
Trans. Vis. Sci. Tech.. 2020; 9(9):26. doi: https://doi.org/10.1167/tvst.9.9.26

Articles August 2020

Factors Affecting Photopic Negative Response Recorded with RET eval System: Study of Young Healthy Subjects

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Kumiko Kato; Asako Sugawara; Ryunosuke Nagashima; Kengo Ikesugi; Masahiko Sugimoto; Mineo Kondo
TAGS: electroretinography, eye, glaucoma, intraocular pressure, linear regression, mydriasis, pupil, ophthalmic examination and evaluation, univariate analysis, retinal nerve fiber layer
Trans. Vis. Sci. Tech.. 2020; 9(9):19. doi: https://doi.org/10.1167/tvst.9.9.19

Articles July 2020

Quality Control Procedures and Baseline Values for Electroretinography, Perimetry, Color Vision, and Visual Acuity in an International Multicenter Study: Observations from a Safety Trial in Chronic Stable Angina Pectoris

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Eberhart Zrenner; Graham E. Holder; Ulrich Schiefer; John M. Wild
TAGS: color vision, electroretinography, eye, perimetry, quality control, baseline value, visual acuity, safety, angina, stable, multicenter studies
Trans. Vis. Sci. Tech.. 2020; 9(8):38. doi: https://doi.org/10.1167/tvst.9.8.38

Includes: Supplemental Content

Special Issue July 2020

Automatic Segmentation of Retinal Capillaries in Adaptive Optics Scanning Laser Ophthalmoscope Perfusion Images Using a Convolutional Neural Network

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Gwen Musial; Hope M. Queener; Suman Adhikari; Hanieh Mirhajianmoghadam; Alexander W. Schill; Nimesh B. Patel; Jason Porter
TAGS: blood capillaries, convolutional neural networks, lasers, ophthalmoscopes, optics, perfusion, pixel
Trans. Vis. Sci. Tech.. 2020; 9(2):43. doi: https://doi.org/10.1167/tvst.9.2.43

Includes: Supplemental Content

Perspective July 2020

Harmonization of Outcomes and Vision Endpoints in Vision Restoration Trials: Recommendations from the International HOVER Taskforce

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Lauren N. Ayton; Joseph F. Rizzo, III; Ian L. Bailey; August Colenbrander; Gislin Dagnelie; Duane R. Geruschat; Philip C. Hessburg; Chris D. McCarthy; Matthew A. Petoe; Gary S. Rubin; Philip R. Troyk; for the HOVER International Taskforce
TAGS: eye, universities, vision
Trans. Vis. Sci. Tech.. 2020; 9(8):25. doi: https://doi.org/10.1167/tvst.9.8.25

Articles July 2020

Decellularizing the Porcine Optic Nerve Head: Toward a Model to Study the Mechanobiology of Glaucoma

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Jr-Jiun Liou; Michelle D. Drewry; Ashlinn Sweeney; Bryan N. Brown; Jonathan P. Vande Geest
TAGS: body tissue, dna, glaucoma, hydrogel, optic disk, suidae, mass or substance concentration per volume, rheology
Trans. Vis. Sci. Tech.. 2020; 9(8):17. doi: https://doi.org/10.1167/tvst.9.8.17

Articles July 2020

Systemic Mesenchymal Stem Cell Treatment Mitigates Structural and Functional Retinal Ganglion Cell Degeneration in a Mouse Model of Multiple Sclerosis

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Oliver W. Gramlich; Alexander J. Brown; Cheyanne R. Godwin; Michael S. Chimenti; Lauren K. Boland; James A. Ankrum; Randy H. Kardon
TAGS: mice, multiple sclerosis, optic neuritis, tissue degeneration, stem cell, mesenchymal, retinal ganglion cells
Trans. Vis. Sci. Tech.. 2020; 9(8):16. doi: https://doi.org/10.1167/tvst.9.8.16

Articles July 2020

Clinical Application of Infrared-Light Microperimetry in the Assessment of Scotopic-Eye Sensitivity

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Grzegorz Łabuz; Asu Rayamajhi; Julia Usinger; Katarzyna Komar; Patrick Merz; Ramin Khoramnia; Grazyna Palczewska; Krzysztof Palczewski; Gerd U. Auffarth
TAGS: eye, infrared rays
Trans. Vis. Sci. Tech.. 2020; 9(8):7. doi: https://doi.org/10.1167/tvst.9.8.7

Articles June 2020

Reliability and Recommended Settings for Pediatric Circumpapillary Retinal Nerve Fiber Layer Imaging Using Hand-Held Optical Coherence Tomography

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Sonal D. Shah; Adnaan Haq; Shafak Toufeeq; Zhanhan Tu; Budor Edawaji; Joseph Abbott; Irene Gottlob; Frank A. Proudlock
TAGS: reliability, retinal nerve fiber layer, diagnostic imaging, pediatrics, optical coherence tomography, hand
Trans. Vis. Sci. Tech.. 2020; 9(7):43. doi: https://doi.org/10.1167/tvst.9.7.43

Includes: Supplemental Content

Articles June 2020

Evaluation of Electrical Performance and Properties of Electroretinography Electrodes

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Tony T. C. Man; Yolanda W. Y. Yip; Frederick K. F. Cheung; Wing Sze Lee; Chi Pui Pang; Mårten Erik Brelén
TAGS: electric impedance, electrolytes, electroretinography, gold, noise, silver, skin
Trans. Vis. Sci. Tech.. 2020; 9(7):45. doi: https://doi.org/10.1167/tvst.9.7.45

Includes: Supplemental Content

Articles June 2020

Repeatability of Scotopic Sensitivity and Dark Adaptation Using a Medmont Dark-Adapted Chromatic Perimeter in Age-related Macular Degeneration

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Durin Uddin; Brett G. Jeffrey; Oliver Flynn; Wai Wong; Henry Wiley; Tiarnan Keenan; Emily Chew; Catherine Cukras
TAGS: age-related macular degeneration, dark adaptation, rod photoreceptors, retinal cone
Trans. Vis. Sci. Tech.. 2020; 9(7):31. doi: https://doi.org/10.1167/tvst.9.7.31

Includes: Supplemental Content

Special Issue June 2020

A Retrospective Comparison of Deep Learning to Manual Annotations for Optic Disc and Optic Cup Segmentation in Fundus Photographs

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Huazhu Fu; Fei Li; Yanwu Xu; Jingan Liao; Jian Xiong; Jianbing Shen; Jiang Liu; Xiulan Zhang; for iChallenge-GON study group
TAGS: deep learning, fundus photography, glaucoma, optic cup, optic disk, retrospective studies, ophthalmologists
Trans. Vis. Sci. Tech.. 2020; 9(2):33. doi: https://doi.org/10.1167/tvst.9.2.33

Includes: Supplemental Content

Articles June 2020

Interpreting MAIA Microperimetry Using Age- and Retinal Loci-Specific Reference Thresholds

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Jason Charng; Paul G. Sanfilippo; Mary S. Attia; Monika Dolliver; Sukanya Arunachalam; Avenell L. Chew; Evan N. Wong; David A. Mackey; Fred K. Chen
TAGS: eye, scotoma
Trans. Vis. Sci. Tech.. 2020; 9(7):19. doi: https://doi.org/10.1167/tvst.9.7.19

Includes: Supplemental Content

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Laser Capture Microdissection-Based RNA Microsequencing Reveals Optic Nerve Crush-Related Early mRNA Alterations in Retinal Ganglion Cell Layer

Probing ON and OFF Retinal Pathways in Glaucoma Using Electroretinography

The RUSH2A Study: Best-Corrected Visual Acuity, Full-Field Electroretinography Amplitudes, and Full-Field Stimulus Thresholds at Baseline

Anatomical Location of the Raphe and Extended Raphe in the Human Retina: Implications for Assessment of the Optic Nerve with OCT

Mitochondrial Transfer of the Mutant Human ND6T14484C Gene Causes Visual Loss and Optic Neuropathy

Artifact Rates for 2D Retinal Nerve Fiber Layer Thickness Versus 3D Neuroretinal Rim Thickness Using Spectral-Domain Optical Coherence Tomography

Dynamics of Contrast Decrement and Increment Responses in Human Visual Cortex

Electrophysiological and Pupillometric Abnormalities in PROM1 Cone–Rod Dystrophy

Factors Affecting Photopic Negative Response Recorded with RET eval System: Study of Young Healthy Subjects

Quality Control Procedures and Baseline Values for Electroretinography, Perimetry, Color Vision, and Visual Acuity in an International Multicenter Study: Observations from a Safety Trial in Chronic Stable Angina Pectoris

Automatic Segmentation of Retinal Capillaries in Adaptive Optics Scanning Laser Ophthalmoscope Perfusion Images Using a Convolutional Neural Network

Harmonization of Outcomes and Vision Endpoints in Vision Restoration Trials: Recommendations from the International HOVER Taskforce

Decellularizing the Porcine Optic Nerve Head: Toward a Model to Study the Mechanobiology of Glaucoma

Systemic Mesenchymal Stem Cell Treatment Mitigates Structural and Functional Retinal Ganglion Cell Degeneration in a Mouse Model of Multiple Sclerosis

Clinical Application of Infrared-Light Microperimetry in the Assessment of Scotopic-Eye Sensitivity

Reliability and Recommended Settings for Pediatric Circumpapillary Retinal Nerve Fiber Layer Imaging Using Hand-Held Optical Coherence Tomography

Evaluation of Electrical Performance and Properties of Electroretinography Electrodes

Repeatability of Scotopic Sensitivity and Dark Adaptation Using a Medmont Dark-Adapted Chromatic Perimeter in Age-related Macular Degeneration

A Retrospective Comparison of Deep Learning to Manual Annotations for Optic Disc and Optic Cup Segmentation in Fundus Photographs

Interpreting MAIA Microperimetry Using Age- and Retinal Loci-Specific Reference Thresholds

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